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Quoted phrase not found in phrase index: "Reduced tissue carnitine O-palmitoyltransferase 2 activity"
Page 1
Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features.
Lehmann D, Motlagh L, Robaa D, Zierz S. Lehmann D, et al. Int J Mol Sci. 2017 Jan 3;18(1):82. doi: 10.3390/ijms18010082. Int J Mol Sci. 2017. PMID: 28054946 Free PMC article. Review.
CPT (carnitine palmitoyltransferase) II muscle deficiency is the most common form of muscle fatty acid metabolism disorders. ...The biochemical consequences of the disease-causing mutations are still discussed controversially. CPT activity in muscles of patients wit …
CPT (carnitine palmitoyltransferase) II muscle deficiency is the most common form of muscle fatty acid metabolism disorders. ...The b …
Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach.
Joshi PR, Zierz S. Joshi PR, et al. Molecules. 2020 Apr 13;25(8):1784. doi: 10.3390/molecules25081784. Molecules. 2020. PMID: 32295037 Free PMC article. Review.
CPT is present in two subforms: CPT I at the outer mitochondrial membrane and carnitine palmitoyltransferase II (CPT II) inside the mitochondria. ...Nevertheless, in some patients, not detectable to reduced total activities are also reported. CPT II protein i …
CPT is present in two subforms: CPT I at the outer mitochondrial membrane and carnitine palmitoyltransferase II (CPT II) inside the m …
Selected metabolic alterations in the ischemic heart and their contributions to arrhythmogenesis.
Corr PB, Yamada KA. Corr PB, et al. Herz. 1995 Jun;20(3):156-68. Herz. 1995. PMID: 7543431 Review.
This suggests that subtle and reversible biochemical and/or ionic alterations within or near the sarcolemma may contribute to the electrophysiologic derangements. Our studies have concentrated on 2 amphipathic metabolites, long-chain acylcarnitines and lysophosphatidylchol …
This suggests that subtle and reversible biochemical and/or ionic alterations within or near the sarcolemma may contribute to the electrophy …
The effect of high-fat diet and inhibition of ceramide production on insulin action in liver.
Zabielski P, Daniluk J, Hady HR, Markowski AR, Imierska M, Górski J, Blachnio-Zabielska AU. Zabielski P, et al. J Cell Physiol. 2019 Feb;234(2):1851-1861. doi: 10.1002/jcp.27058. Epub 2018 Aug 1. J Cell Physiol. 2019. PMID: 30067865
Liver, as one of the most important organs involved in lipids and glucose metabolism, is perceived as a key tissue for pharmacotherapy of insulin resistance (IRes) and type 2 diabetes. Ceramides (Cer) are biologically active lipids, which accumulation is asso …
Liver, as one of the most important organs involved in lipids and glucose metabolism, is perceived as a key tissue for pharmacotherap …
Extracts from Aralia elata (Miq) Seem alleviate hepatosteatosis via improving hepatic insulin sensitivity.
Hwang KA, Hwang YJ, Kim GR, Choe JS. Hwang KA, et al. BMC Complement Altern Med. 2015 Oct 5;15:347. doi: 10.1186/s12906-015-0871-5. BMC Complement Altern Med. 2015. PMID: 26438035 Free PMC article.
After 3 weeks of AE extract treatment, we performed oral glucose tolerance test (OGTT). Liver tissue was procured for histological examination, Phosphoinositide 3-kinase (PI3K) and Protein kinase B (PKB/Akt) activity. ...Additionally, AE extract decreased PI3K and A …
After 3 weeks of AE extract treatment, we performed oral glucose tolerance test (OGTT). Liver tissue was procured for histological ex …
Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise.
Holloway GP, Bezaire V, Heigenhauser GJ, Tandon NN, Glatz JF, Luiken JJ, Bonen A, Spriet LL. Holloway GP, et al. J Physiol. 2006 Feb 15;571(Pt 1):201-10. doi: 10.1113/jphysiol.2005.102178. Epub 2005 Dec 15. J Physiol. 2006. PMID: 16357012 Free PMC article.
In rat skeletal muscle, the transport of LCFA at the level of mitochondria is regulated by carnitine palmitoyltransferase I (CPTI) activity and the content of malonyl-CoA (M-CoA); however, this relationship is not consistently observed in humans. ...Whole body fat o …
In rat skeletal muscle, the transport of LCFA at the level of mitochondria is regulated by carnitine palmitoyltransferase I (CPTI) …
Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes.
Watt MJ, Southgate RJ, Holmes AG, Febbraio MA. Watt MJ, et al. J Mol Endocrinol. 2004 Oct;33(2):533-44. doi: 10.1677/jme.1.01499. J Mol Endocrinol. 2004. PMID: 15525607
Fatty acids are an important ligand for peroxisome proliferator-activated receptor (PPAR) activation and transcriptional regulation of metabolic genes. ...NA resulted in a marked (3- to 6-fold) increase (P<0.05) in PPARalpha, PPARdelta and PPAR coactivator 1alpha …
Fatty acids are an important ligand for peroxisome proliferator-activated receptor (PPAR) activation and transcriptional regul …
Reduced plasma free fatty acid availability during exercise: effect on gene expression.
Tunstall RJ, McAinch AJ, Hargreaves M, van Loon LJ, Cameron-Smith D. Tunstall RJ, et al. Eur J Appl Physiol. 2007 Mar;99(5):485-93. doi: 10.1007/s00421-006-0376-5. Epub 2006 Dec 22. Eur J Appl Physiol. 2007. PMID: 17186295 Clinical Trial.
Initial studies using L6 myotubes demonstrated dose responsive sensitivity for both PDK4 and PGC-1alpha mRNA to acute FA exposure in vitro. Nine active males performed two trials consisting of 2 h exercise, followed by 2 h of recovery. In one trial, plasma FA …
Initial studies using L6 myotubes demonstrated dose responsive sensitivity for both PDK4 and PGC-1alpha mRNA to acute FA exposure in vitro. …
Downregulation of fatty acid oxidation by involvement of HIF-1α and PPARγ in human gastric adenocarcinoma and related clinical significance.
Ezzeddini R, Taghikhani M, Salek Farrokhi A, Somi MH, Samadi N, Esfahani A, Rasaee MJ. Ezzeddini R, et al. J Physiol Biochem. 2021 May;77(2):249-260. doi: 10.1007/s13105-021-00791-3. Epub 2021 Mar 17. J Physiol Biochem. 2021. PMID: 33730333
Serum concentrations of medium and long-chain acyl-CoA dehydrogenases (MCAD and LCAD) proteins were measured using ELISA, and local expression of HIF-1alpha, carnitine palmitoyl transferase 1 (CPT1A) and peroxisome proliferator-activated receptor gamma (PPARgamma) w …
Serum concentrations of medium and long-chain acyl-CoA dehydrogenases (MCAD and LCAD) proteins were measured using ELISA, and local expressi …
Transcriptional metabolic inflexibility in skeletal muscle among individuals with increasing insulin resistance.
Jans A, Sparks LM, van Hees AM, Gjelstad IM, Tierney AC, Risérus U, Drevon CA, Roche HM, Schrauwen P, Blaak EE. Jans A, et al. Obesity (Silver Spring). 2011 Nov;19(11):2158-66. doi: 10.1038/oby.2011.149. Epub 2011 Jun 23. Obesity (Silver Spring). 2011. PMID: 21701566 Free article.
Interestingly, peroxisome proliferator-activated receptor coactivator 1alpha (PGC1alpha), peroxisome proliferator-activated receptor alpha (PPARalpha), and muscle carnitine palmitoyl transferase 1b (mCPT1), important for oxidative metabolism, showed a complex …
Interestingly, peroxisome proliferator-activated receptor coactivator 1alpha (PGC1alpha), peroxisome proliferator-activated re …
12 results