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Quoted phrase not found in phrase index: "Reduced T cell CD40 expression"
Page 1
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Yang F, He Z, Duan H, Zhang D, Li J, Yang H, Dorsey JF, Zou W, Nabavizadeh SA, Bagley SJ, Abdullah K, Brem S, Zhang L, Xu X, Byrne KT, Vonderheide RH, Gong Y, Fan Y. Yang F, et al. Nat Commun. 2021 Jun 8;12(1):3424. doi: 10.1038/s41467-021-23832-3. Nat Commun. 2021. PMID: 34103524 Free PMC article.
Consistent with a pro-tumor role of IL-6 in alternative Ms polarization, we here show that targeting IL-6 by genetic ablation or pharmacological inhibition moderately improves T-cell infiltration into GBM and enhances mouse survival; however, IL-6 inhibition does no …
Consistent with a pro-tumor role of IL-6 in alternative Ms polarization, we here show that targeting IL-6 by genetic ablation or pharmacolog …
Red blood cell storage lesion.
Kor DJ, Van Buskirk CM, Gajic O. Kor DJ, et al. Bosn J Basic Med Sci. 2009 Oct;9 Suppl 1(Suppl 1):S21-S27. doi: 10.17305/bjbms.2009.2750. Bosn J Basic Med Sci. 2009. PMID: 19912115 Free PMC article. Review.
The accumulation of biologic response modifiers such as soluble CD40 ligand (sCD40L), lysophosphatidylcholine (lyso-PC), and Regulated on Activation, Normal T-cell Expressed and Secreted (RANTES) have been associated with altered recipient immune funct …
The accumulation of biologic response modifiers such as soluble CD40 ligand (sCD40L), lysophosphatidylcholine (lyso-PC), and Regulate …
Regulatory T cells and minimal change nephropathy: in the midst of a complex network.
Bertelli R, Bonanni A, Di Donato A, Cioni M, Ravani P, Ghiggeri GM. Bertelli R, et al. Clin Exp Immunol. 2016 Feb;183(2):166-74. doi: 10.1111/cei.12675. Epub 2015 Oct 12. Clin Exp Immunol. 2016. PMID: 26147676 Free PMC article. Review.
CD80, CD40) are expressed by podocytes under inflammatory stimuli, representing a direct potential mechanism for proteinuria. ...Blocking antigen-presenting cells with cytotoxic T lymphocyte antigen (CTLA-4)-Ig fusion molecules inhibiting CD80 and/or with blockers o …
CD80, CD40) are expressed by podocytes under inflammatory stimuli, representing a direct potential mechanism for proteinuria. …
The mosaic of immunosuppressive drugs.
Masri MA. Masri MA. Mol Immunol. 2003 Jul;39(17-18):1073-7. doi: 10.1016/s0161-5890(03)00075-0. Mol Immunol. 2003. PMID: 12835079 Review.
Recognition is followed by the ligation of a series of adhesion molecules starting with an antigen to its specific T-cell receptor (TCR)/cluster of differentiation (CD) complex, expressed on the surface of the T cell. ...Rapamycin, which is simi …
Recognition is followed by the ligation of a series of adhesion molecules starting with an antigen to its specific T-cell rece …
Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs.
Joks R, Durkin HG. Joks R, et al. Pharmacol Res. 2011 Dec;64(6):602-9. doi: 10.1016/j.phrs.2011.04.001. Epub 2011 Apr 9. Pharmacol Res. 2011. PMID: 21501686 Review.
The tetracyclines affect an epsilon specific pathway because IgM, IgG and IgA responses did not decrease. Further, in humans, DTH responses to recall antigens did not decrease. In related studies, we found that two distinct T cell subsets: CD4+CD60 negative a …
The tetracyclines affect an epsilon specific pathway because IgM, IgG and IgA responses did not decrease. Further, in humans, DTH responses …
Intravenous Immunoglobulin Therapy Restores the Quantity and Phenotype of Circulating Dendritic Cells and CD4+ T Cells in Children With Acute Kawasaki Disease.
Wang N, Chen Z, Zhang F, Zhang Q, Sun L, Lv H, Wang B, Shen J, Zhou X, Chen F, Zhang B, Meng L, Zhou H, Bai Z, Huang J. Wang N, et al. Front Immunol. 2022 Feb 10;13:802690. doi: 10.3389/fimmu.2022.802690. eCollection 2022. Front Immunol. 2022. PMID: 35222381 Free PMC article.
RESULTS: Patients with KD exhibited fewer peripheral DC subsets and CD4(+) T cells than HCs. Human leucocyte antigen-DR (HLA-DR) expression was reduced on CD1c(+) myeloid DCs (CD1c(+) mDCs), whereas that on plasmacytoid DCs (pDCs) did not change significantly. Both …
RESULTS: Patients with KD exhibited fewer peripheral DC subsets and CD4(+) T cells than HCs. Human leucocyte antigen-DR (HLA-DR) expressi …
Human CD4+ T Helper Cell Responses after Tick-Borne Encephalitis Vaccination and Infection.
Aberle JH, Schwaiger J, Aberle SW, Stiasny K, Scheinost O, Kundi M, Chmelik V, Heinz FX. Aberle JH, et al. PLoS One. 2015 Oct 14;10(10):e0140545. doi: 10.1371/journal.pone.0140545. eCollection 2015. PLoS One. 2015. PMID: 26465323 Free PMC article.
This study provides a comprehensive analysis of the cytokine patterns of CD4+ T cell responses in 20 humans after TBE vaccination in comparison to those in 18 patients with TBEV infection. ...We show that TBEV-specific CD4+ T cell responses are polyfun …
This study provides a comprehensive analysis of the cytokine patterns of CD4+ T cell responses in 20 humans after TBE vaccinat …
Suppression of the immunologic response to peanut during immunotherapy is often transient.
Gorelik M, Narisety SD, Guerrerio AL, Chichester KL, Keet CA, Bieneman AP, Hamilton RG, Wood RA, Schroeder JT, Frischmeyer-Guerrerio PA. Gorelik M, et al. J Allergy Clin Immunol. 2015 May;135(5):1283-92. doi: 10.1016/j.jaci.2014.11.010. Epub 2014 Dec 24. J Allergy Clin Immunol. 2015. PMID: 25542883 Free PMC article.
Peanut- and dust mite-induced expression of TH2 cytokines was reduced in DC-T-cell cocultures during immunotherapy. This was associated with decreased levels of CD40, HLA-DR, and CD86 expression on DCs and increased expression of C …
Peanut- and dust mite-induced expression of TH2 cytokines was reduced in DC-T-cell cocultures during immunothera …
PD-L1- and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease.
Galea R, Nel HJ, Talekar M, Liu X, Ooi JD, Huynh M, Hadjigol S, Robson KJ, Ting YT, Cole S, Cochlin K, Hitchcock S, Zeng B, Yekollu S, Boks M, Goh N, Roberts H, Rossjohn J, Reid HH, Boyd BJ, Malaviya R, Shealy DJ, Baker DG, Madakamutil L, Kitching AR, O'Sullivan BJ, Thomas R. Galea R, et al. JCI Insight. 2019 Sep 19;4(18):e126025. doi: 10.1172/jci.insight.126025. JCI Insight. 2019. PMID: 31487265 Free PMC article.
Autoimmune diseases resulting from MHC class II-restricted autoantigen-specific T cell immunity include the systemic inflammatory autoimmune conditions rheumatoid arthritis and vasculitis. ...Peptide/calcitriol liposomes modulated CD40 expression by hu …
Autoimmune diseases resulting from MHC class II-restricted autoantigen-specific T cell immunity include the systemic inflammat …
Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.
Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA. Ishihara J, et al. Mol Cancer Ther. 2018 Nov;17(11):2399-2411. doi: 10.1158/1535-7163.MCT-18-0091. Epub 2018 Aug 10. Mol Cancer Ther. 2018. PMID: 30097487
CD40 is an immune costimulatory receptor expressed by antigen-presenting cells. ...Moreover, in a genetically engineered Braf(V600E) betaCat(STA) melanoma model that does not respond to checkpoint inhibitors, PlGF-2(123-144)-anti-CD40 antibody treatment enhan …
CD40 is an immune costimulatory receptor expressed by antigen-presenting cells. ...Moreover, in a genetically engineered Braf( …
87 results