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Quoted phrase not found in phrase index: "Reduced brain N-acetyl aspartate level by MRS"
Page 1
Usefulness of magnetic resonance spectroscopy in mesial temporal sclerosis: a systematic review.
Fernández-Vega N, Ramos-Rodriguez JR, Alfaro F, Barbancho MÁ, García-Casares N. Fernández-Vega N, et al. Neuroradiology. 2021 Sep;63(9):1395-1405. doi: 10.1007/s00234-021-02704-z. Epub 2021 Apr 13. Neuroradiology. 2021. PMID: 33851253 Review.
BACKGROUND: Magnetic resonance spectroscopy (MRS) provides non-invasive information about metabolic features in different regions of the brain affected by mesial temporal sclerosis (MTS). ...Nine studies also found reduced NAA levels in extrahippocampa …
BACKGROUND: Magnetic resonance spectroscopy (MRS) provides non-invasive information about metabolic features in different regions of …
Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status.
Yang YS, Smucny J, Zhang H, Maddock RJ. Yang YS, et al. Neuroimage Clin. 2023;39:103461. doi: 10.1016/j.nicl.2023.103461. Epub 2023 Jun 27. Neuroimage Clin. 2023. PMID: 37406595 Free PMC article. Review.
BACKGROUND: Brain metabolite abnormalities measured with magnetic resonance spectroscopy (MRS) provide insight into pathological processes in schizophrenia. Prior meta-analyses have not yet answered important questions about the influence of clinical and technical f …
BACKGROUND: Brain metabolite abnormalities measured with magnetic resonance spectroscopy (MRS) provide insight into pathologic …
Magnetic Resonance Spectroscopy in Alzheimer's Disease: Systematic Review and Meta-Analysis.
Wang H, Tan L, Wang HF, Liu Y, Yin RH, Wang WY, Chang XL, Jiang T, Yu JT. Wang H, et al. J Alzheimers Dis. 2015;46(4):1049-70. doi: 10.3233/JAD-143225. J Alzheimers Dis. 2015. PMID: 26402632 Review.
METHODS: Using Hedges' g effect size, a systematic search was performed in PubMed, Cochrane Library, Ovid, Embase, and EBSCO, and 38 studies were integrated into the final meta-analysis. RESULTS: According to the observational studies, N-acetyl aspartate (NAA …
METHODS: Using Hedges' g effect size, a systematic search was performed in PubMed, Cochrane Library, Ovid, Embase, and EBSCO, and 38 studies …
Magnetic Resonance Spectroscopy (MRS) in Alzheimer's Disease.
Sheikh-Bahaei N, Chen M, Pappas I. Sheikh-Bahaei N, et al. Methods Mol Biol. 2024;2785:115-142. doi: 10.1007/978-1-0716-3774-6_9. Methods Mol Biol. 2024. PMID: 38427192
MRS is a noninvasive technique to measure different metabolites in the brain. Changes in the levels of certain metabolites can be used as surrogate markers for Alzheimer's disease. ...
MRS is a noninvasive technique to measure different metabolites in the brain. Changes in the levels of certain metaboli …
Cerebrospinal Fluid Amyloid Beta, Tau Levels, Apolipoprotein, and (1)H-MRS Brain Metabolites in Alzheimer's Disease: A Systematic Review.
Piersson AD, Mohamad M, Rajab F, Suppiah S. Piersson AD, et al. Acad Radiol. 2021 Oct;28(10):1447-1463. doi: 10.1016/j.acra.2020.06.006. Epub 2020 Jul 7. Acad Radiol. 2021. PMID: 32651050 Review.
RESULTS: Twenty four articles met the inclusion criteria. Decreased levels of N-acetyl aspartate (NAA), NAA/(creatine) Cr, and NAA/(myo-inositol) ml, and increased ml, ml/Cr, Cho (choline)/Cr, and ml/NAA were found in the posterior cingulate cortex/pre …
RESULTS: Twenty four articles met the inclusion criteria. Decreased levels of N-acetyl aspartate (NAA), NAA/(cre …
Reduced Insular Glutamine and N-acetylaspartate in systemic lupus erythematosus: a single-voxel (1)H-MR spectroscopy study.
Cagnoli P, Harris RE, Frechtling D, Berkis G, Gracley RH, Graft CC, Lowe SE, Chenevert TL, McCune WJ, Gebarski S, Sundgren PC. Cagnoli P, et al. Acad Radiol. 2013 Oct;20(10):1286-96. doi: 10.1016/j.acra.2013.07.011. Acad Radiol. 2013. PMID: 24029061 Free PMC article.
RESULTS: NPSLE patients had significantly reduced N-acetylaspartate (NAA)/creatine compared to HC (P = .02) and SLE patients (P = .01) in the RI. Lower glutamine/creatine levels were also detected in RI in both patient groups and in frontal white matte …
RESULTS: NPSLE patients had significantly reduced N-acetylaspartate (NAA)/creatine compared to HC (P = .02) and SLE pat …
The impact of cannabidiol treatment on resting state functional connectivity, prefrontal metabolite levels and reward processing in recent-onset patients with a psychotic disorder.
van Boxel R, Gangadin SS, Janssen H, van der Steur S, van der Vinne LJC, Dortants L, Pelgrim TAD, Draisma LWR, Tuura R, van der Meer P, Batalla A, Bossong MG. van Boxel R, et al. J Psychiatr Res. 2023 Jul;163:93-101. doi: 10.1016/j.jpsychires.2023.05.019. Epub 2023 May 13. J Psychiatr Res. 2023. PMID: 37207437 Free article. Clinical Trial.
Although there were no significant treatment effects on prefrontal metabolite concentrations, we showed that decreased positive symptom severity over time was associated with both diminishing glutamate (p = 0.029) and N-acetyl-aspartate (NAA; neuronal integri …
Although there were no significant treatment effects on prefrontal metabolite concentrations, we showed that decreased positive symptom seve …
Denoising magnetic resonance spectroscopy (MRS) data using stacked autoencoder for improving signal-to-noise ratio and speed of MRS.
Wang J, Ji B, Lei Y, Liu T, Mao H, Yang X. Wang J, et al. Med Phys. 2023 Dec;50(12):7955-7966. doi: 10.1002/mp.16831. Epub 2023 Nov 10. Med Phys. 2023. PMID: 37947479
PURPOSE: We propose to use deep-learning approaches to denoise MRS data without increasing NSA. This method has potential to reduce the acquisition time as well as improve SNR and quality of spectra, which could enhance the diagnostic value and broaden the clinical …
PURPOSE: We propose to use deep-learning approaches to denoise MRS data without increasing NSA. This method has potential to reduc …
Chemical genetic activation of the cholinergic basal forebrain hippocampal circuit rescues memory loss in Alzheimer's disease.
Liu W, Li J, Yang M, Ke X, Dai Y, Lin H, Wang S, Chen L, Tao J. Liu W, et al. Alzheimers Res Ther. 2022 Apr 13;14(1):53. doi: 10.1186/s13195-022-00994-w. Alzheimers Res Ther. 2022. PMID: 35418161 Free PMC article.
We then employed a chemogenetic strategy to selectively activate the cholinergic circuit from the medial septal nucleus (MS) and the vertical limb of the diagonal band nucleus (VDB) on the basal forebrain to the hippocampus. MRS and immunoblotting techniques were used to m …
We then employed a chemogenetic strategy to selectively activate the cholinergic circuit from the medial septal nucleus (MS) and the vertica …
Diffusion MRI and MR spectroscopy reveal microstructural and metabolic brain alterations in chronic mild stress exposed rats: A CMS recovery study.
Khan AR, Hansen B, Wiborg O, Kroenke CD, Jespersen SN. Khan AR, et al. Neuroimage. 2018 Feb 15;167:342-353. doi: 10.1016/j.neuroimage.2017.11.053. Epub 2017 Nov 28. Neuroimage. 2018. PMID: 29196269 Free PMC article.
CMS exposure induced a significant metabolic alteration in vHP, and significant microstructural alterations were observed in the HP, AM, and PFC in comparison to the age match control and within the anhedonic group. A significantly high level of N-acetylaspartate …
CMS exposure induced a significant metabolic alteration in vHP, and significant microstructural alterations were observed in the HP, AM, and …
85 results