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Quoted phrase not found in phrase index: "Reduced brain N-acetyl aspartate level by MRS"
Page 1
The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial.
Ford TC, Downey LA, Simpson T, McPhee G, Oliver C, Stough C. Ford TC, et al. Nutrients. 2018 Dec 1;10(12):1860. doi: 10.3390/nu10121860. Nutrients. 2018. PMID: 30513795 Free PMC article. Clinical Trial.
A diet rich in B-group vitamins is essential for optimal body and brain function, and insufficient amounts of such vitamins have been associated with higher levels of neural inflammation and oxidative stress, as marked by increased blood plasma homocysteine. ...Resu …
A diet rich in B-group vitamins is essential for optimal body and brain function, and insufficient amounts of such vitamins have been …
Brain N-Acetyl Aspartate and associations with cognitive impairment in alcohol dependent patients.
Morley KC, Lagopoulos J, Logge W, Chitty K, Moustafa AA, Haber PS. Morley KC, et al. J Clin Exp Neuropsychol. 2020 Mar;42(2):111-117. doi: 10.1080/13803395.2019.1685078. Epub 2019 Nov 7. J Clin Exp Neuropsychol. 2020. PMID: 31698988
Introduction: Chronic alcohol consumption has been observed to be associated with a range of cognitive impairments that impact on treatment management. In this spectroscopy study, we examined the association of N-Acetyl Aspartate (NAA), a marker of neuronal i …
Introduction: Chronic alcohol consumption has been observed to be associated with a range of cognitive impairments that impact on treatment …
Brain mitochondrial dysfunction and driving simulator performance in untreated obstructive sleep apnea.
Vakulin A, Green MA, D'Rozario AL, Stevens D, Openshaw H, Bartlett D, Wong K, McEvoy RD, Grunstein RR, Rae CD. Vakulin A, et al. J Sleep Res. 2022 Apr;31(2):e13482. doi: 10.1111/jsr.13482. Epub 2021 Sep 15. J Sleep Res. 2022. PMID: 34528315
Vulnerability to this neurobehavioral impairment may be explained by lower brain metabolites levels involved in mitochondrial metabolism. This study compared markers of brain energy metabolism in OSA patients identified as vulnerable vs resistant to driving i …
Vulnerability to this neurobehavioral impairment may be explained by lower brain metabolites levels involved in mitochondrial …
A comparative study of posterior cingulate metabolism in patients with mild cognitive impairment due to Parkinson's disease or Alzheimer's disease.
Huang M, Yu H, Cai X, Zhang Y, Pu W, Gao B. Huang M, et al. Sci Rep. 2023 Aug 30;13(1):14241. doi: 10.1038/s41598-023-41569-5. Sci Rep. 2023. PMID: 37648724 Free PMC article.
Few comparative studies have assessed metabolic brain changes in cognitive impairment among neurodegenerative disorders, and the posterior cingulate cortex (PCC) is a metabolically active brain region with high involvement in multiple cognitive processes. ...Compare …
Few comparative studies have assessed metabolic brain changes in cognitive impairment among neurodegenerative disorders, and the post …
N-acetylaspartylglutamate (NAAG) and N-acetylaspartate (NAA) in patients with schizophrenia.
Jessen F, Fingerhut N, Sprinkart AM, Kühn KU, Petrovsky N, Maier W, Schild HH, Block W, Wagner M, Träber F. Jessen F, et al. Schizophr Bull. 2013 Jan;39(1):197-205. doi: 10.1093/schbul/sbr127. Epub 2011 Sep 12. Schizophr Bull. 2013. PMID: 21914645 Free PMC article.
NAAG provides a component of the proton magnetic resonance spectrum (1H-MRS) in humans. The signal of NAAG, however, largely overlaps with its precursor and degrading product N-acetylaspartate (NAA) that by itself does not act in glutamatergic neurotransmissi …
NAAG provides a component of the proton magnetic resonance spectrum (1H-MRS) in humans. The signal of NAAG, however, largely overlaps …
Longitudinal Metabolite Changes in Progressive Multiple Sclerosis: A Study of 3 Potential Neuroprotective Treatments.
John NA, Solanky BS, De Angelis F, Parker RA, Weir CJ, Stutters J, Carrasco FP, Schneider T, Doshi A, Calvi A, Williams T, Plantone D, Monteverdi A, MacManus D, Marshall I, Barkhof F, Gandini Wheeler-Kingshott CAM, Chataway J; MS‐SMART Investigators. John NA, et al. J Magn Reson Imaging. 2024 Jun;59(6):2192-2201. doi: 10.1002/jmri.29017. Epub 2023 Oct 3. J Magn Reson Imaging. 2024. PMID: 37787109 Clinical Trial.
BACKGROUND: (1)H-magnetic resonance spectroscopy ((1)H-MRS) may provide a direct index for the testing of medicines for neuroprotection and drug mechanisms in multiple sclerosis (MS) through measures of total N-acetyl-aspartate (tNAA), total creatine ( …
BACKGROUND: (1)H-magnetic resonance spectroscopy ((1)H-MRS) may provide a direct index for the testing of medicines for neuroprotecti …
Hippocampal metabolites in asthma and their implications for cognitive function.
Kroll JL, Steele AM, Pinkham AE, Choi C, Khan DA, Patel SV, Chen JR, Aslan S, Sherwood Brown E, Ritz T. Kroll JL, et al. Neuroimage Clin. 2018 Apr 12;19:213-221. doi: 10.1016/j.nicl.2018.04.012. eCollection 2018. Neuroimage Clin. 2018. PMID: 30035015 Free PMC article.
Participants underwent 3-Tesla sMRI and (1)H-MRS, with the volume of interest placed in the left hippocampus to measure levels of N-acetylaspartate (NAA), glutamate (Glu), creatine (Cr), and myo-inositol (MI), as indicators of neuronal viability, cellu …
Participants underwent 3-Tesla sMRI and (1)H-MRS, with the volume of interest placed in the left hippocampus to measure levels …
Reduced Insular Glutamine and N-acetylaspartate in systemic lupus erythematosus: a single-voxel (1)H-MR spectroscopy study.
Cagnoli P, Harris RE, Frechtling D, Berkis G, Gracley RH, Graft CC, Lowe SE, Chenevert TL, McCune WJ, Gebarski S, Sundgren PC. Cagnoli P, et al. Acad Radiol. 2013 Oct;20(10):1286-96. doi: 10.1016/j.acra.2013.07.011. Acad Radiol. 2013. PMID: 24029061 Free PMC article.
RESULTS: NPSLE patients had significantly reduced N-acetylaspartate (NAA)/creatine compared to HC (P = .02) and SLE patients (P = .01) in the RI. Lower glutamine/creatine levels were also detected in RI in both patient groups and in frontal white matte …
RESULTS: NPSLE patients had significantly reduced N-acetylaspartate (NAA)/creatine compared to HC (P = .02) and SLE pat …
The impact of cannabidiol treatment on resting state functional connectivity, prefrontal metabolite levels and reward processing in recent-onset patients with a psychotic disorder.
van Boxel R, Gangadin SS, Janssen H, van der Steur S, van der Vinne LJC, Dortants L, Pelgrim TAD, Draisma LWR, Tuura R, van der Meer P, Batalla A, Bossong MG. van Boxel R, et al. J Psychiatr Res. 2023 Jul;163:93-101. doi: 10.1016/j.jpsychires.2023.05.019. Epub 2023 May 13. J Psychiatr Res. 2023. PMID: 37207437 Free article. Clinical Trial.
Although there were no significant treatment effects on prefrontal metabolite concentrations, we showed that decreased positive symptom severity over time was associated with both diminishing glutamate (p = 0.029) and N-acetyl-aspartate (NAA; neuronal integri …
Although there were no significant treatment effects on prefrontal metabolite concentrations, we showed that decreased positive symptom seve …
Determination of Brain Metabolite T(1) Without Interference From Macromolecule Relaxation.
An L, Araneta MF, Victorino M, Shen J. An L, et al. J Magn Reson Imaging. 2020 Nov;52(5):1352-1359. doi: 10.1002/jmri.27259. Epub 2020 Jul 3. J Magn Reson Imaging. 2020. PMID: 32618104 Free PMC article.
STATISTICAL TESTS: Cramer-Rao lower bound (CRLB), within-subject coefficient of variation, and F-test. RESULTS: The T(1) relaxation times of N-acetylaspartate (NAA), total creatine (tCr), total choline (tCho), myo-inositol (mI), and glutamate (Glu) were determined w …
STATISTICAL TESTS: Cramer-Rao lower bound (CRLB), within-subject coefficient of variation, and F-test. RESULTS: The T(1) relaxation times of …
93 results