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Quoted phrase not found in phrase index: "Reduced epidermal keratin protein expression"
Page 1
Filaggrin and Skin Barrier Function.
Kezic S, Jakasa I. Kezic S, et al. Curr Probl Dermatol. 2016;49:1-7. doi: 10.1159/000441539. Epub 2016 Feb 4. Curr Probl Dermatol. 2016. PMID: 26844893 Review.
The interior of the corneocytes consists mainly of keratin filaments aggregated by filaggrin (FLG) protein. Next, together with several other proteins, FLG is cross-linked into a mechanically robust cornified cell envelope providing a scaffold for the extrace …
The interior of the corneocytes consists mainly of keratin filaments aggregated by filaggrin (FLG) protein. Next, together wit …
Clinical and Histological Effects of Topical Epidermal Growth Factor on Acne and Acne Scars.
Kim DH, Yang JH, Cho SI, Yoon JY, Kim JW, Choi S, Suh DH. Kim DH, et al. Dermatology. 2022;238(5):837-845. doi: 10.1159/000521294. Epub 2022 Jan 25. Dermatology. 2022. PMID: 35078198
RESULTS: Acne and acne scars were significantly improved on EGFO-treated sides, while control sides were not. Acne lesion and scar counts were significantly reduced after 4 weeks, while IGA, SGA, and ECCA grade significantly decreased after 8 weeks. Immunohistochemistry sh …
RESULTS: Acne and acne scars were significantly improved on EGFO-treated sides, while control sides were not. Acne lesion and scar counts we …
hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers.
Lima Cunha D, Oram A, Gruber R, Plank R, Lingenhel A, Gupta MK, Altmüller J, Nürnberg P, Schmuth M, Zschocke J, Šarić T, Eckl KM, Hennies HC. Lima Cunha D, et al. Int J Mol Sci. 2021 Feb 11;22(4):1785. doi: 10.3390/ijms22041785. Int J Mol Sci. 2021. PMID: 33670118 Free PMC article.
For this purpose, we have generated hiPSCs from patients with congenital ichthyosis, either non-syndromic autosomal recessive congenital ichthyosis (ARCI) or the ichthyosis syndrome trichothiodystrophy (TTD). hiPSCs were successfully differentiated into basal keratinocyte-like ce …
For this purpose, we have generated hiPSCs from patients with congenital ichthyosis, either non-syndromic autosomal recessive congenital ich …
Nociceptin/orphanin FQ opioid peptide-receptor expression in pachyonychia congenita.
Pan B, Schröder W, Jostock R, Schwartz M, Rosson G, Polydefkis M. Pan B, et al. J Peripher Nerv Syst. 2018 Dec;23(4):241-248. doi: 10.1111/jns.12288. Epub 2018 Oct 16. J Peripher Nerv Syst. 2018. PMID: 30255608
Robust NOP-R expression was detected in epidermal keratinocytes and in a subset of PGP9.5+ fibers in both epidermis and dermis, confirmed by western blot and absorption experiments with NOP-R peptide. ...Furthermore, most SP+ fibers also co-expressed N …
Robust NOP-R expression was detected in epidermal keratinocytes and in a subset of PGP9.5+ fibers in both epidermis and …
Whole exome sequencing in Alopecia Areata identifies rare variants in KRT82.
Erjavec SO, Gelfman S, Abdelaziz AR, Lee EY, Monga I, Alkelai A, Ionita-Laza I, Petukhova L, Christiano AM. Erjavec SO, et al. Nat Commun. 2022 Feb 10;13(1):800. doi: 10.1038/s41467-022-28343-3. Nat Commun. 2022. PMID: 35145093 Free PMC article.
KRT82 encodes a hair-specific type II keratin that is exclusively expressed in the hair shaft cuticle during anagen phase, and its expression is decreased in Alopecia Areata patient skin and hair follicles. Finally, we find that cases with an identified damag …
KRT82 encodes a hair-specific type II keratin that is exclusively expressed in the hair shaft cuticle during anagen phase, and …
Keratin 17 is overexpressed and predicts poor survival in estrogen receptor-negative/human epidermal growth factor receptor-2-negative breast cancer.
Merkin RD, Vanner EA, Romeiser JL, Shroyer ALW, Escobar-Hoyos LF, Li J, Powers RS, Burke S, Shroyer KR. Merkin RD, et al. Hum Pathol. 2017 Apr;62:23-32. doi: 10.1016/j.humpath.2016.10.006. Epub 2016 Nov 2. Hum Pathol. 2017. PMID: 27816721
Clinicopathological features of breast cancer have limited accuracy to predict survival. By immunohistochemistry (IHC), keratin 17 (K17) expression has been correlated with triple-negative status (estrogen receptor [ER]/progesterone receptor/human epidermal g …
Clinicopathological features of breast cancer have limited accuracy to predict survival. By immunohistochemistry (IHC), keratin 17 (K …
Proteomic profiling reveals candidate markers for arsenic-induced skin keratosis.
Guo Z, Hu Q, Tian J, Yan L, Jing C, Xie HQ, Bao W, Rice RH, Zhao B, Jiang G. Guo Z, et al. Environ Pollut. 2016 Nov;218:34-38. doi: 10.1016/j.envpol.2016.08.035. Epub 2016 Aug 20. Environ Pollut. 2016. PMID: 27552035
Samples from non-exposed healthy individuals served as controls. We found that three proteins in arsenic-exposed lesional epidermis were consistently distinguishably expressed from the unaffected epidermis. ...The expression of keratin 6c …
Samples from non-exposed healthy individuals served as controls. We found that three proteins in arsenic-exposed lesional epidermi …
Small interfering RNA targeting of keratin 17 reduces inflammation in imiquimod-induced psoriasis-like dermatitis.
Xiao CY, Zhu ZL, Zhang C, Fu M, Qiao HJ, Wang G, Dang EL. Xiao CY, et al. Chin Med J (Engl). 2020 Nov 20;133(24):2910-2918. doi: 10.1097/CM9.0000000000001197. Chin Med J (Engl). 2020. PMID: 33237695 Free PMC article.
Thus, there is an urgent need to find a more effective therapy for this disease. Keratin 17 (K17), a type I intermediate filament, is overexpressed in the psoriatic epidermis and plays a critical pathogenic role by stimulating T cells in psoriasis. ...Thus, gene …
Thus, there is an urgent need to find a more effective therapy for this disease. Keratin 17 (K17), a type I intermediate filament, is …
Expression of syndecan-1 and expression of epidermal growth factor receptor are associated with survival in patients with nonsmall cell lung carcinoma.
Shah L, Walter KL, Borczuk AC, Kawut SM, Sonett JR, Gorenstein LA, Ginsburg ME, Steinglass KM, Powell CA. Shah L, et al. Cancer. 2004 Oct 1;101(7):1632-8. doi: 10.1002/cncr.20542. Cancer. 2004. PMID: 15378500 Free article.
METHODS: Associations between patient survival and immunostaining for 11 representative histologic classifiers (epidermal growth factor receptor [EGFR], CDK4, syndecan-1, singed-like, TTF-1, keratin 5, HDAC2, docking protein 1, integrin alpha3, P63, and cycli …
METHODS: Associations between patient survival and immunostaining for 11 representative histologic classifiers (epidermal growth fact …
Activation of PPARgamma and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As3+-transformed UROtsa cells.
Mehus AA, Bergum N, Knutson P, Shrestha S, Zhou XD, Garrett SH, Sens DA, Sens MA, Somji S. Mehus AA, et al. PLoS One. 2020 Aug 21;15(8):e0237976. doi: 10.1371/journal.pone.0237976. eCollection 2020. PLoS One. 2020. PMID: 32822399 Free PMC article.
Muscle invasive urothelial cancer (MIUC) are grouped into basal or luminal molecular subtypes based on their gene expression profile. The basal subtype is more aggressive and can be associated with squamous differentiation, characterized by high expression of …
Muscle invasive urothelial cancer (MIUC) are grouped into basal or luminal molecular subtypes based on their gene expression p …
37 results