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Quoted phrase not found in phrase index: "Reduced epidermal keratin protein expression"
Page 1
Reduced Expression of KRT17 Predicts Poor Prognosis in HER2(high) Breast Cancer.
Tang S, Liu W, Yong L, Liu D, Lin X, Huang Y, Wang H, Cai F. Tang S, et al. Biomolecules. 2022 Aug 25;12(9):1183. doi: 10.3390/biom12091183. Biomolecules. 2022. PMID: 36139022 Free PMC article.
ROC analysis revealed that KRT17 expression had moderate diagnostic value. Interestingly, decreased expression of KRT17 was significantly correlated with poor prognosis in BC patients, especially in HER2(high) and ER(high) patients. ...KRT17 was found to be i …
ROC analysis revealed that KRT17 expression had moderate diagnostic value. Interestingly, decreased expression of KRT17 was si …
The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis.
Hoesl C, Fröhlich T, Posch C, Kneitz H, Goebeler M, Schneider MR, Dahlhoff M. Hoesl C, et al. Mol Oncol. 2021 Aug;15(8):2140-2155. doi: 10.1002/1878-0261.12945. Epub 2021 Mar 31. Mol Oncol. 2021. PMID: 33786987 Free PMC article.
Here, we analyzed the function of LRIG1 during chemically induced skin carcinogenesis in transgenic mice expressing LRIG1 in the skin under the control of the keratin 5 promoter (LRIG1-TG mice). ...In conclusion, our study demonstrated that LRIG1-TG mice develop mel …
Here, we analyzed the function of LRIG1 during chemically induced skin carcinogenesis in transgenic mice expressing LRIG1 in the skin …
Immunocyto- and histochemical profiling of nucleostemin expression: marker of epidermal stem cells?
Lacina L, Smetana K Jr, Dvoránková B, Stork J, Plzáková Z, Gabius HJ. Lacina L, et al. J Dermatol Sci. 2006 Nov;44(2):73-80. doi: 10.1016/j.jdermsci.2006.08.008. Epub 2006 Sep 26. J Dermatol Sci. 2006. PMID: 17000083
In addition, probing the value of this protein as a marker of epidermal stem cells was an aim of this study. ...Part of these cells also expressed keratin 19. FaDu cells were strongly positive, illustrating expression in malignant cells which re …
In addition, probing the value of this protein as a marker of epidermal stem cells was an aim of this study. ...Part of these …
Keratin 17 is overexpressed and predicts poor survival in estrogen receptor-negative/human epidermal growth factor receptor-2-negative breast cancer.
Merkin RD, Vanner EA, Romeiser JL, Shroyer ALW, Escobar-Hoyos LF, Li J, Powers RS, Burke S, Shroyer KR. Merkin RD, et al. Hum Pathol. 2017 Apr;62:23-32. doi: 10.1016/j.humpath.2016.10.006. Epub 2016 Nov 2. Hum Pathol. 2017. PMID: 27816721
Clinicopathological features of breast cancer have limited accuracy to predict survival. By immunohistochemistry (IHC), keratin 17 (K17) expression has been correlated with triple-negative status (estrogen receptor [ER]/progesterone receptor/human epiderma …
Clinicopathological features of breast cancer have limited accuracy to predict survival. By immunohistochemistry (IHC), keratin …
A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex.
Tan TS, Common JEA, Lim JSY, Badowski C, Firdaus MJ, Leonardi SS, Lane EB. Tan TS, et al. J Cell Sci. 2021 Oct 1;134(19):jcs258409. doi: 10.1242/jcs.258409. Epub 2021 Oct 13. J Cell Sci. 2021. PMID: 34643242 Free PMC article.
Screening of a protein kinase inhibitor library identified several candidates that reduced aggregates and impacted on epidermal growth factor receptor (EGFR) signalling. ...EBS keratinocytes treated with a known EGFR inhibitor, afatinib, were driven out of ac …
Screening of a protein kinase inhibitor library identified several candidates that reduced aggregates and impacted on epide …
CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer.
Xu H, Wu K, Tian Y, Liu Q, Han N, Yuan X, Zhang L, Wu GS, Wu K. Xu H, et al. Int J Oncol. 2016 Oct;49(4):1343-50. doi: 10.3892/ijo.2016.3639. Epub 2016 Jul 29. Int J Oncol. 2016. PMID: 27499099 Free PMC article.
Western blot assays demonstrated that erlotinib treatment decreased the expression of CD44, accompanied with the reduced protein levels of mesenchymal and cancer stem cell markers. Collectively, this study suggested that the expression of CD44 was upre …
Western blot assays demonstrated that erlotinib treatment decreased the expression of CD44, accompanied with the reduced pr …
Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer.
Guler G, Huebner K, Himmetoglu C, Jimenez RE, Costinean S, Volinia S, Pilarski RT, Hayran M, Shapiro CL. Guler G, et al. Cancer. 2009 Feb 15;115(4):899-908. doi: 10.1002/cncr.24103. Cancer. 2009. PMID: 19130459 Free PMC article.
BACKGROUND: The expression of fragile histidine triad protein (Fhit) and WW domain-containing oxidoreductase protein (Wwox), tumor suppressors that are encoded by fragile (FRA) loci FRA3B and FRA16D, are lost concordantly in breast cancers. ...Reduced …
BACKGROUND: The expression of fragile histidine triad protein (Fhit) and WW domain-containing oxidoreductase protein (W …
Reduced expression of insulin-like growth factor-binding protein-3 (IGFBP-3) in Squamous cell carcinoma complicating recessive dystrophic epidermolysis bullosa.
Mallipeddi R, Wessagowit V, South AP, Robson AM, Orchard GE, Eady RA, McGrath JA. Mallipeddi R, et al. J Invest Dermatol. 2004 May;122(5):1302-9. doi: 10.1111/j.0022-202X.2004.22525.x. J Invest Dermatol. 2004. PMID: 15140235 Free article.
Currently, little is known about the molecular pathology or cell biology of SCC in RDEB. In this study, we compared gene expression in RDEB SCC (n=3) and non-EB SCC (n=3) with corresponding RDEB and non-EB peri-tumoral skin, with microarray analysis using DermArray …
Currently, little is known about the molecular pathology or cell biology of SCC in RDEB. In this study, we compared gene expressio …
Epidermal growth factor induces cytokeratin 19 expression accompanied by increased growth abilities in human hepatocellular carcinoma.
Yoneda N, Sato Y, Kitao A, Ikeda H, Sawada-Kitamura S, Miyakoshi M, Harada K, Sasaki M, Matsui O, Nakanuma Y. Yoneda N, et al. Lab Invest. 2011 Feb;91(2):262-72. doi: 10.1038/labinvest.2010.161. Epub 2010 Sep 20. Lab Invest. 2011. PMID: 20856226 Free article.
In vivo experiments using human HCC specimens obtained from a total of 78 patients and clinicopathological analysis were also performed. Among the growth factors tested, epidermal growth factor (EGF) had prominent effects on inducing CK19 expression in PLC-5 and Hep …
In vivo experiments using human HCC specimens obtained from a total of 78 patients and clinicopathological analysis were also performed. Amo …
Intracellular calprotectin (S100A8/A9) controls epithelial differentiation and caspase-mediated cleavage of EGFR in head and neck squamous cell carcinoma.
Argyris PP, Slama Z, Malz C, Koutlas IG, Pakzad B, Patel K, Kademani D, Khammanivong A, Herzberg MC. Argyris PP, et al. Oral Oncol. 2019 Aug;95:1-10. doi: 10.1016/j.oraloncology.2019.05.027. Epub 2019 Jun 4. Oral Oncol. 2019. PMID: 31345374 Free PMC article.
We seek to characterize the suppressive role of calprotectin in HNSCC. AIMS: (1) Investigate changes in S100A8/A9 expression as oral carcinogenesis progresses and (2) determine whether intracellular calprotectin can regulate epidermal growth factor receptor (EGFR), …
We seek to characterize the suppressive role of calprotectin in HNSCC. AIMS: (1) Investigate changes in S100A8/A9 expression as oral …
17 results