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Short-term effectiveness of ruxolitinib in the treatment of recurrent or refractory hemophagocytic lymphohistiocytosis in children.
Wei A, Ma H, Li Z, Zhang L, Zhang Q, Wang D, Lian H, Zhang R, Wang T. Wei A, et al. Int J Hematol. 2020 Oct;112(4):568-576. doi: 10.1007/s12185-020-02936-4. Epub 2020 Jul 14. Int J Hematol. 2020. PMID: 32666469
To investigate the efficacy and safety of the Janus kinase inhibitor ruxolitinib in the treatment of recurrent or refractory hemophagocytic lymphohistiocytosis (HLH) in children. We performed a retrospective analysis of ruxolitinib in children with recurrent …
To investigate the efficacy and safety of the Janus kinase inhibitor ruxolitinib in the treatment of recurrent or refractory hemop …
Treatment of refractory hemophagocytic lymphohistiocytosis with emapalumab despite severe concurrent infections.
Lounder DT, Bin Q, de Min C, Jordan MB. Lounder DT, et al. Blood Adv. 2019 Jan 8;3(1):47-50. doi: 10.1182/bloodadvances.2018025858. Blood Adv. 2019. PMID: 30617216 Free PMC article.
Neutralization of IFN-gamma with emapalumab can reverse severe, refractory hemophagocytic lymphohistiocytosis. Neutralizing IFN-gamma did not impair control of multiple viral and other infections in a severely ill patient....
Neutralization of IFN-gamma with emapalumab can reverse severe, refractory hemophagocytic lymphohistiocytosis. Neutrali …