Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1995 1
1996 2
1997 1
1999 1
2000 2
2001 1
2002 4
2004 3
2005 3
2006 1
2007 3
2008 1
2009 5
2010 1
2011 1
2012 1
2013 9
2014 3
2015 7
2016 12
2017 5
2018 10
2019 15
2020 12
2021 9
2022 9
2023 12
2024 6

Text availability

Article attribute

Article type

Publication date

Search Results

130 results

Results by year

Filters applied: . Clear all
Page 1
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, Xiao A, Tian J, Xie L, Zhou M, Hu Z, Zhu F, Xu X, Hou F, Nie J. Xu S, et al. EBioMedicine. 2022 Dec;86:104312. doi: 10.1016/j.ebiom.2022.104312. Epub 2022 Nov 4. EBioMedicine. 2022. PMID: 36335669 Free PMC article.
BACKGROUND: The role of the IL6 family members in organ fibrosis, including renal interstitial fibrosis (TIF), has been widely explored. However, few studies have ever simultaneously examined them in the same cohort of patients. ...
BACKGROUND: The role of the IL6 family members in organ fibrosis, including renal interstitial fibrosis (TIF), has been …
Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation.
Tao Y, Tang C, Wei J, Shan Y, Fang X, Li Y. Tao Y, et al. Mol Med. 2023 May 9;29(1):63. doi: 10.1186/s10020-023-00657-y. Mol Med. 2023. PMID: 37161357 Free PMC article.
BACKGROUND: Renal interstitial fibrosis (RIF) is a common pathway to end-stage renal disease regardless of the initial etiology. ...RESULTS: The results showed that Nr4a1 was upregulated in UUO mouse kidneys, and was positively correlated with the degree of i …
BACKGROUND: Renal interstitial fibrosis (RIF) is a common pathway to end-stage renal disease regardless of the initial …
Molecular genetics of renal ciliopathies.
Barroso-Gil M, Olinger E, Sayer JA. Barroso-Gil M, et al. Biochem Soc Trans. 2021 Jun 30;49(3):1205-1220. doi: 10.1042/BST20200791. Biochem Soc Trans. 2021. PMID: 33960378 Review.
Renal ciliopathies are a heterogenous group of inherited disorders leading to an array of phenotypes that include cystic kidney disease and renal interstitial fibrosis leading to progressive chronic kidney disease and end-stage kidney disease. ...
Renal ciliopathies are a heterogenous group of inherited disorders leading to an array of phenotypes that include cystic kidney disease and …
Current Opinion for Hypertension in Renal Fibrosis.
Sun HJ. Sun HJ. Adv Exp Med Biol. 2019;1165:37-47. doi: 10.1007/978-981-13-8871-2_3. Adv Exp Med Biol. 2019. PMID: 31399960 Review.
Hypertensive nephropathy is the second leading cause of death in chronic kidney disease (CKD) around the world. Long-time hypertension loading results in renal interstitial fibrosis, which is associated with aberrant activation of renal fibroblasts and excess …
Hypertensive nephropathy is the second leading cause of death in chronic kidney disease (CKD) around the world. Long-time hypertension loadi …
Nicotine promotes renal interstitial fibrosis via upregulation of XIAP in an alpha7-nAChR-dependent manner.
Guo L, Zhang Y, Lu J, Li X, Zhang C, Song W, Dong Y, Zhou X, Li R. Guo L, et al. Mol Cell Endocrinol. 2023 Oct 1;576:111989. doi: 10.1016/j.mce.2023.111989. Epub 2023 Jul 13. Mol Cell Endocrinol. 2023. PMID: 37451424
In addition, the nuclear translocation and transcriptional activity of SP1 were promoted when nicotine bound to alpha7-nAChR, resulting in XIAP overexpression and renal interstitial fibrosis progression. This phenotype can be reversed by the nicotine receptor …
In addition, the nuclear translocation and transcriptional activity of SP1 were promoted when nicotine bound to alpha7-nAChR, resulting in X …
Hemodynamics of hyperuricemia.
Sánchez-Lozada LG, Tapia E, Rodríguez-Iturbe B, Johnson RJ, Herrera-Acosta J. Sánchez-Lozada LG, et al. Semin Nephrol. 2005 Jan;25(1):19-24. doi: 10.1016/j.semnephrol.2004.09.004. Semin Nephrol. 2005. PMID: 15660330 Review.
Hyperuricemic rats developed hypertension, afferent arteriolar thickening, and mild renal interstitial fibrosis. Additionally, hyperuricemia accelerated renal damage and vascular disease in rats undergoing renal ablation. ...
Hyperuricemic rats developed hypertension, afferent arteriolar thickening, and mild renal interstitial fibrosis. Additi …
Aldosterone promotes renal interstitial fibrosis via the AIF-1/AKT/mTOR signaling pathway.
Yuan X, Wang X, Li Y, Li X, Zhang S, Hao L. Yuan X, et al. Mol Med Rep. 2019 Nov;20(5):4033-4044. doi: 10.3892/mmr.2019.10680. Epub 2019 Sep 13. Mol Med Rep. 2019. PMID: 31545432 Free PMC article.
A number of studies have shown that aldosterone serves an important role in promoting renal interstitial fibrosis, although the specific mechanism remains to be elucidated. ...Suppressing the expression of AIF-1 inhibited the effects of aldosterone, whereas t …
A number of studies have shown that aldosterone serves an important role in promoting renal interstitial fibrosis, alth …
Value of multiparametric magnetic resonance imaging for evaluating chronic kidney disease and renal fibrosis.
Hua C, Qiu L, Zhou L, Zhuang Y, Cai T, Xu B, Hao S, Fang X, Wang L, Jiang H. Hua C, et al. Eur Radiol. 2023 Aug;33(8):5211-5221. doi: 10.1007/s00330-023-09674-1. Epub 2023 May 6. Eur Radiol. 2023. PMID: 37148348
OBJECTIVES: To identify optimized MRI markers for evaluating chronic kidney disease (CKD) and renal interstitial fibrosis (IF). MATERIALS AND METHODS: This prospective study included 43 patients with CKD and 20 controls. ...Support vector machine (SVM) combin …
OBJECTIVES: To identify optimized MRI markers for evaluating chronic kidney disease (CKD) and renal interstitial fibrosis …
Chrysophanol ameliorates renal interstitial fibrosis by inhibiting the TGF-beta/Smad signaling pathway.
Dou F, Ding Y, Wang C, Duan J, Wang W, Xu H, Zhao X, Wang J, Wen A. Dou F, et al. Biochem Pharmacol. 2020 Oct;180:114079. doi: 10.1016/j.bcp.2020.114079. Epub 2020 Jun 6. Biochem Pharmacol. 2020. PMID: 32511988
Renal interstitial fibrosis (RIF) is a major pathological feature of chronic kidney disease at middle and end stages. ...
Renal interstitial fibrosis (RIF) is a major pathological feature of chronic kidney disease at middle and end stages. . …
130 results