mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN.
Rai P, Plagov A, Lan X, Chandel N, Singh T, Lederman R, Ayasolla KR, Mathieson PW, Saleem MA, Husain M, Malhotra A, Chander PN, Singhal PC.
Rai P, et al.
Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F343-54. doi: 10.1152/ajprenal.00135.2013. Epub 2013 May 15.
Am J Physiol Renal Physiol. 2013.
PMID: 23678040
Free PMC article.
We hypothesized that mammalian target of rapamycin (mTOR) may be critical for the induction of p53-mediated oxidative kidney cell injury in HIVAN. To test our hypothesis, we evaluated the effect of an mTOR inhibitor, rapamycin, on kidney cell p53 expression, downstr …
We hypothesized that mammalian target of rapamycin (mTOR) may be critical for the induction of p53-mediated oxidative kidney cell inj …