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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 2
1997 1
1998 3
1999 1
2000 3
2001 7
2002 5
2003 5
2004 5
2005 8
2006 4
2007 4
2008 4
2009 12
2010 12
2011 9
2012 14
2013 27
2014 24
2015 27
2016 31
2017 37
2018 41
2019 47
2020 57
2021 59
2022 60
2023 57
2024 32

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532 results

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Page 1
Mitochondrial dysfunction and the AKI-to-CKD transition.
Jiang M, Bai M, Lei J, Xie Y, Xu S, Jia Z, Zhang A. Jiang M, et al. Am J Physiol Renal Physiol. 2020 Dec 1;319(6):F1105-F1116. doi: 10.1152/ajprenal.00285.2020. Epub 2020 Oct 19. Am J Physiol Renal Physiol. 2020. PMID: 33073587 Free article. Review.
Even milder AKI has adverse consequences and could progress to renal fibrosis, which is the ultimate common pathway for various terminal kidney diseases. ...
Even milder AKI has adverse consequences and could progress to renal fibrosis, which is the ultimate common pathway for variou …
Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents.
Wang X, Yang S, Li S, Zhao L, Hao Y, Qin J, Zhang L, Zhang C, Bian W, Zuo L, Gao X, Zhu B, Lei XG, Gu Z, Cui W, Xu X, Li Z, Zhu B, Li Y, Chen S, Guo H, Zhang H, Sun J, Zhang M, Hui Y, Zhang X, Liu X, Sun B, Wang L, Qiu Q, Zhang Y, Li X, Liu W, Xue R, Wu H, Shao D, Li J, Zhou Y, Li S, Yang R, Pedersen OB, Yu Z, Ehrlich SD, Ren F. Wang X, et al. Gut. 2020 Dec;69(12):2131-2142. doi: 10.1136/gutjnl-2019-319766. Epub 2020 Apr 2. Gut. 2020. PMID: 32241904 Free PMC article.
Microbiota from patients transplanted to renal injured germ-free mice or antibiotic-treated rats induce higher production of serum uraemic toxins and aggravated renal fibrosis and oxidative stress more than microbiota from controls. ...
Microbiota from patients transplanted to renal injured germ-free mice or antibiotic-treated rats induce higher production of serum uraemic t …
Research Advances in the Mechanisms of Hyperuricemia-Induced Renal Injury.
Su HY, Yang C, Liang D, Liu HF. Su HY, et al. Biomed Res Int. 2020 Jun 26;2020:5817348. doi: 10.1155/2020/5817348. eCollection 2020. Biomed Res Int. 2020. PMID: 32685502 Free PMC article. Review.
In this review, we focus on the research advances in the mechanisms of hyperuricemia-caused renal injury, primarily on oxidative stress, endothelial dysfunction, renal fibrosis, and inflammation. Furthermore, we discuss the progress in hyperuricemia management....
In this review, we focus on the research advances in the mechanisms of hyperuricemia-caused renal injury, primarily on oxidative stress, end …
Mechanism and application of metformin in kidney diseases: An update.
Song A, Zhang C, Meng X. Song A, et al. Biomed Pharmacother. 2021 Jun;138:111454. doi: 10.1016/j.biopha.2021.111454. Epub 2021 Mar 11. Biomed Pharmacother. 2021. PMID: 33714781 Free article. Review.
As the common pathway for chronic kidney disease (CKD) progressing towards end-stage renal disease (ESRD), renal fibrosis is ameliorated by metformin, to a great extent dependent on AMPK activation. ...
As the common pathway for chronic kidney disease (CKD) progressing towards end-stage renal disease (ESRD), renal fibrosis is a …
Ganoderic acid hinders renal fibrosis via suppressing the TGF-beta/Smad and MAPK signaling pathways.
Geng XQ, Ma A, He JZ, Wang L, Jia YL, Shao GY, Li M, Zhou H, Lin SQ, Ran JH, Yang BX. Geng XQ, et al. Acta Pharmacol Sin. 2020 May;41(5):670-677. doi: 10.1038/s41401-019-0324-7. Epub 2019 Dec 5. Acta Pharmacol Sin. 2020. PMID: 31804606 Free PMC article.
Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases (CKD) to the end stage of renal diseases (ESRD). ...The inhibitory effects of GA on TGF-beta/Smad and MAPK signaling pathways were confirmed in TGF-beta1-stimulated HK-2 cell …
Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases (CKD) to the end stage of renal dis …
A new LKB1 activator, piericidin analogue S14, retards renal fibrosis through promoting autophagy and mitochondrial homeostasis in renal tubular epithelial cells.
Liu C, Wang X, Wang X, Zhang Y, Min W, Yu P, Miao J, Shen W, Chen S, Zhou S, Li X, Meng P, Wu Q, Hou FF, Liu Y, Yang P, Wang C, Lin X, Tang L, Zhou X, Zhou L. Liu C, et al. Theranostics. 2022 Oct 9;12(16):7158-7179. doi: 10.7150/thno.78376. eCollection 2022. Theranostics. 2022. PMID: 36276641 Free PMC article.
Background: Liver kinase B1 (LKB1) is the key regulator of energy metabolism and cell homeostasis. LKB1 dysfunction plays a key role in renal fibrosis. However, LKB1 activators are scarce in commercial nowadays. ...Conclusion: PA-S14 is a novel leading compound of L …
Background: Liver kinase B1 (LKB1) is the key regulator of energy metabolism and cell homeostasis. LKB1 dysfunction plays a key role in r …
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
Li X, Zou Y, Xing J, Fu YY, Wang KY, Wan PZ, Zhai XY. Li X, et al. Oxid Med Cell Longev. 2020 Jan 20;2020:6286984. doi: 10.1155/2020/6286984. eCollection 2020. Oxid Med Cell Longev. 2020. PMID: 32051732 Free PMC article.
The present study investigated the protective role of FG-4592 pretreatment at the early stage of the kidney injury and long-term impact on the progression of renal fibrosis. FG-4592 was administrated two days before FA injection in mice. ...
The present study investigated the protective role of FG-4592 pretreatment at the early stage of the kidney injury and long-term impact on t …
Aging-Related Kidney Diseases.
Kitai Y, Nangaku M, Yanagita M. Kitai Y, et al. Contrib Nephrol. 2021;199:266-273. doi: 10.1159/000517708. Epub 2021 Aug 3. Contrib Nephrol. 2021. PMID: 34343996 Review.
Decreased renal oxygen levels, mitochondrial dysfunction, and inflammation drive renal fibrosis, one of the hallmarks of renal aging. Prevention and Treatment: Novel therapeutic approaches that target these functional changes are now being developed to prevent an ag …
Decreased renal oxygen levels, mitochondrial dysfunction, and inflammation drive renal fibrosis, one of the hallmarks of renal …
Chronic Allograft Injury.
Langewisch E, Mannon RB. Langewisch E, et al. Clin J Am Soc Nephrol. 2021 Nov;16(11):1723-1729. doi: 10.2215/CJN.15590920. Epub 2021 Apr 5. Clin J Am Soc Nephrol. 2021. PMID: 33820759 Free PMC article. Review.
532 results