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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1993 1
1994 2
1996 3
1997 3
1998 1
1999 2
2000 4
2001 5
2002 6
2003 7
2004 9
2005 10
2006 7
2007 9
2008 16
2009 16
2010 11
2011 6
2012 20
2013 30
2014 30
2015 25
2016 31
2017 40
2018 58
2019 71
2020 65
2021 60
2022 50
2023 39
2024 17

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575 results

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Page 1
Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury.
Yao W, Chen Y, Li Z, Ji J, You A, Jin S, Ma Y, Zhao Y, Wang J, Qu L, Wang H, Xiang C, Wang S, Liu G, Bai F, Yang L. Yao W, et al. Adv Sci (Weinh). 2022 Apr;9(12):e2103675. doi: 10.1002/advs.202103675. Epub 2022 Feb 3. Adv Sci (Weinh). 2022. PMID: 35112806 Free PMC article.
Acute kidney injury (AKI) is a complex clinical disorder associated with poor outcomes. Targeted regulation of the degree of inflammation has been a potential strategy for AKI management. ...Targeting the S100a8/a9 signaling with small-molecule inhibitors exhibits renal pr …
Acute kidney injury (AKI) is a complex clinical disorder associated with poor outcomes. Targeted regulation of the degree of inflamma …
Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
Li R, Guo Y, Zhang Y, Zhang X, Zhu L, Yan T. Li R, et al. Int J Mol Sci. 2019 Mar 4;20(5):1103. doi: 10.3390/ijms20051103. Int J Mol Sci. 2019. PMID: 30836660 Free PMC article.
Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect. However, the role of Sal on renal fibrosis has not yet been elucidated. Here, the purpose of t …
Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities …
Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents.
Wang X, Yang S, Li S, Zhao L, Hao Y, Qin J, Zhang L, Zhang C, Bian W, Zuo L, Gao X, Zhu B, Lei XG, Gu Z, Cui W, Xu X, Li Z, Zhu B, Li Y, Chen S, Guo H, Zhang H, Sun J, Zhang M, Hui Y, Zhang X, Liu X, Sun B, Wang L, Qiu Q, Zhang Y, Li X, Liu W, Xue R, Wu H, Shao D, Li J, Zhou Y, Li S, Yang R, Pedersen OB, Yu Z, Ehrlich SD, Ren F. Wang X, et al. Gut. 2020 Dec;69(12):2131-2142. doi: 10.1136/gutjnl-2019-319766. Epub 2020 Apr 2. Gut. 2020. PMID: 32241904 Free PMC article.
Microbiota from patients transplanted to renal injured germ-free mice or antibiotic-treated rats induce higher production of serum uraemic toxins and aggravated renal fibrosis and oxidative stress more than microbiota from controls. ...TRIAL REGISTRATION NUMB …
Microbiota from patients transplanted to renal injured germ-free mice or antibiotic-treated rats induce higher production of serum uraemic t …
Ganoderic acid hinders renal fibrosis via suppressing the TGF-beta/Smad and MAPK signaling pathways.
Geng XQ, Ma A, He JZ, Wang L, Jia YL, Shao GY, Li M, Zhou H, Lin SQ, Ran JH, Yang BX. Geng XQ, et al. Acta Pharmacol Sin. 2020 May;41(5):670-677. doi: 10.1038/s41401-019-0324-7. Epub 2019 Dec 5. Acta Pharmacol Sin. 2020. PMID: 31804606 Free PMC article.
Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases (CKD) to the end stage of renal diseases (ESRD). ...The inhibitory effects of GA on TGF-beta/Smad and MAPK signaling pathways were confirmed in TGF-beta1-stimulated HK-2 cell …
Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases (CKD) to the end stage of renal dis …
Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review.
Alugoju P, Krishna Swamy VKD, Anthikapalli NVA, Tencomnao T. Alugoju P, et al. Crit Rev Food Sci Nutr. 2023;63(31):10709-10774. doi: 10.1080/10408398.2022.2084600. Epub 2022 Jun 16. Crit Rev Food Sci Nutr. 2023. PMID: 35708049 Review.
The present review summarizes the protective molecular mechanisms of actions of astaxanthin on age-related diseases of multiple organs such as Neurodegenerative diseases [Alzheimer's disease (AD), Parkinson's disease (PD), Stroke, Multiple Sclerosis (MS), Amyotrophic lateral scle …
The present review summarizes the protective molecular mechanisms of actions of astaxanthin on age-related diseases of multiple organs such …
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis.
Zhang B, Chen X, Ru F, Gan Y, Li B, Xia W, Dai G, He Y, Chen Z. Zhang B, et al. Cell Death Dis. 2021 Sep 11;12(9):843. doi: 10.1038/s41419-021-04137-1. Cell Death Dis. 2021. PMID: 34511597 Free PMC article.
Renal fibrosis is a common pathological process that occurs with diverse etiologies in chronic kidney disease. ...Lip-1 may potentially be used as a therapeutic approach for the treatment of UUO-induced renal fibrosis....
Renal fibrosis is a common pathological process that occurs with diverse etiologies in chronic kidney disease. ...Lip-1 may po …
Delayed treatment with an autophagy inhibitor 3-MA alleviates the progression of hyperuricemic nephropathy.
Shi Y, Tao M, Ma X, Hu Y, Huang G, Qiu A, Zhuang S, Liu N. Shi Y, et al. Cell Death Dis. 2020 Jun 17;11(6):467. doi: 10.1038/s41419-020-2673-z. Cell Death Dis. 2020. PMID: 32555189 Free PMC article.
Administration of 3-MA at 21 days following after uric acid injury protected kidney from hyperuricemic-related injuries, as demonstrated by improving renal dysfunction and architecture damage, blocking Beclin-1 and LC3II/I and decreasing the number of autophagic vacuoles. Late tr …
Administration of 3-MA at 21 days following after uric acid injury protected kidney from hyperuricemic-related injuries, as demonstrated by …
Dapagliflozin Attenuates Contrast-induced Acute Kidney Injury by Regulating the HIF-1α/HE4/NF-κB Pathway.
Huang X, Guo X, Yan G, Zhang Y, Yao Y, Qiao Y, Wang D, Chen G, Zhang W, Tang C, Cao F. Huang X, et al. J Cardiovasc Pharmacol. 2022 Jun 1;79(6):904-913. doi: 10.1097/FJC.0000000000001268. J Cardiovasc Pharmacol. 2022. PMID: 35383661 Free PMC article.
Previous studies have shown that hypoxia activates HIF-1alpha/HE4/NF-kappaB to enhance renal fibrosis, and the SGLT-2 inhibitor luseogliflozin inhibits hypoxia-inducible factor (HIF)-1alpha expression to reduce the progression of diabetic nephropathy. ...
Previous studies have shown that hypoxia activates HIF-1alpha/HE4/NF-kappaB to enhance renal fibrosis, and the SGLT-2 inhibito …
Chronic Allograft Injury.
Langewisch E, Mannon RB. Langewisch E, et al. Clin J Am Soc Nephrol. 2021 Nov;16(11):1723-1729. doi: 10.2215/CJN.15590920. Epub 2021 Apr 5. Clin J Am Soc Nephrol. 2021. PMID: 33820759 Free PMC article. Review.
Magnesium in renal fibrosis.
Long M, Zhu X, Wei X, Zhao D, Jiang L, Li C, Jin D, Miao C, Du Y. Long M, et al. Int Urol Nephrol. 2022 Aug;54(8):1881-1889. doi: 10.1007/s11255-022-03118-3. Epub 2022 Jan 20. Int Urol Nephrol. 2022. PMID: 35060008 Review.
PURPOSE: Renal fibrosis (RF) is the main pathological feature of chronic kidney disease (CKD). ...Magnesium may also regulate TRPM6/7, promote the secretion of klotho protein and improve renal fibrosis. Therefore, Mg(2+) can protect the kidney from dam …
PURPOSE: Renal fibrosis (RF) is the main pathological feature of chronic kidney disease (CKD). ...Magnesium may also regulate …
575 results