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Disorders of distal nephron function.
Sebastian A, Hulter HN, Kurtz I, Maher T, Schambelan M. Sebastian A, et al. Am J Med. 1982 Feb;72(2):289-307. doi: 10.1016/0002-9343(82)90822-1. Am J Med. 1982. PMID: 6277192 Review.
The pathophysiologic features of the following disorders of distal nephron function are reviewed: (1) pseudohypoaldosteronism, a heterogenous group of disorders in which the signs and symptoms are suggestive of aldosterone deficiency, but in which aldosterone levels are supernorm …
The pathophysiologic features of the following disorders of distal nephron function are reviewed: (1) pseudohypoaldosteronism, a heterogenou …
Idiopathic Hypokalemia in Lupus Nephritis: A Newly Recognized Entity.
Adomako EA, Bilal S, Liu YL, Malik A, Van Buren PN, Shastri S, Sambandam KK. Adomako EA, et al. Kidney360. 2021 Aug 6;2(10):1553-1559. doi: 10.34067/KID.0004352021. eCollection 2021 Oct 28. Kidney360. 2021. PMID: 35372968 Free PMC article.
BACKGROUND: Various causes of hypokalemia (HK) from renal potassium wasting, including distal renal tubular acidosis (RTA), have been described in lupus nephritis (LN). ...
BACKGROUND: Various causes of hypokalemia (HK) from renal potassium wasting, including distal renal tubular acidosis (R …
Case Report: Renal potassium wasting in SARS-CoV-2 infection.
Mabillard H, Tedd H, Speight A, Duncan C, Price DA, Sayer JA. Mabillard H, et al. F1000Res. 2020 Jun 30;9:659. doi: 10.12688/f1000research.24621.2. eCollection 2020. F1000Res. 2020. PMID: 33299549 Free PMC article.
Early reports suggest that hypokalaemia may frequent those with SARS-CoV-2 infection and various aetiological factors may cause this electrolyte disturbance. A Chinese retrospective study has demonstrated renal potassium wasting in patients infected with SARS …
Early reports suggest that hypokalaemia may frequent those with SARS-CoV-2 infection and various aetiological factors may cause this electro …
Circadian variation in renal sodium and potassium handling in cirrhosis. The role of aldosterone, cortisol, sympathoadrenergic tone, and intratubular factors.
Trevisani F, Bernardi M, De Palma R, Pancione L, Capani F, Baraldini M, Ligabue A, Gasbarrini G. Trevisani F, et al. Gastroenterology. 1989 Apr;96(4):1187-98. doi: 10.1016/0016-5085(89)91640-5. Gastroenterology. 1989. PMID: 2925063
Aldosterone is the main cause of sodium retention in nonazotemic ascitic patients, while sympathoadrenergic hyperactivity may contribute to preserve renal perfusion. The influence of aldosterone on kaliuresis is enhanced, but renal potassium wasting in patien …
Aldosterone is the main cause of sodium retention in nonazotemic ascitic patients, while sympathoadrenergic hyperactivity may contribute to …
Peculiar electrolytic and hormonal abnormalities in acute renal failure due to leptospirosis.
Abdulkader RC, Seguro AC, Malheiro PS, Burdmann EA, Marcondes M. Abdulkader RC, et al. Am J Trop Med Hyg. 1996 Jan;54(1):1-6. doi: 10.4269/ajtmh.1996.54.1. Am J Trop Med Hyg. 1996. PMID: 8651360
These results strongly suggest that hypokalemia in leptospirosis ARF is due to renal potassium wasting potentialized by aldosterone and cortisol, requiring that special attention is given to potassium replacement as well as to volume repletion in the treatmen …
These results strongly suggest that hypokalemia in leptospirosis ARF is due to renal potassium wasting potentialized by …
Bartter's syndrome in Arabic children: review of 13 cases.
Abdel-al YK, Badawi MH, Yaeesh SA, Habib YQ, al-Khuffash FA, al-Ghanim MM, al-Najidi AK. Abdel-al YK, et al. Pediatr Int. 1999 Jun;41(3):299-303. doi: 10.1046/j.1442-200x.1999.01056.x. Pediatr Int. 1999. PMID: 10365582
BACKGROUND: Bartter's syndrome (BS) is an inherited disease of renal potassium wasting characterized by hypokalemic alkalosis, normal blood pressure, vascular insensitivity to pressor agents and elevated plasma concentrations of renin and aldosterone. ...
BACKGROUND: Bartter's syndrome (BS) is an inherited disease of renal potassium wasting characterized by hypokalemic alk …
Lipid-based nutrient supplements containing vitamins and minerals attenuate renal electrolyte loss in HIV/AIDS patients starting antiretroviral therapy: A randomized controlled trial in Zambia.
Munkombwe D, Muungo TL, Michelo C, Kelly P, Chirwa S, Filteau S. Munkombwe D, et al. Clin Nutr ESPEN. 2016 Jun;13:e8-e14. doi: 10.1016/j.clnesp.2016.03.002. Epub 2016 Apr 1. Clin Nutr ESPEN. 2016. PMID: 28531643 Clinical Trial.
The fractional excretion of potassium (FEK) was not significantly different at baseline between the two groups (p = 0.69) but the values were above normal physiological ranges (i.e. >6.4%) reflecting renal potassium wasting. However, FEK was significantly …
The fractional excretion of potassium (FEK) was not significantly different at baseline between the two groups (p = 0.69) but the values wer …
A case of adult-onset Bartter's syndrome.
Park JW, Chung YJ, Yeum CH, Lee JJ, Yoo KS, Kim SW, Kim NH, Choi KC, Kang YJ. Park JW, et al. Korean J Intern Med. 1995 Jan;10(1):60-3. doi: 10.3904/kjim.1995.10.1.60. Korean J Intern Med. 1995. PMID: 7626559 Free PMC article.
Bartter's Syndrome is characterized by renal potassium wasting with hypokalemia, metabolic alkalosis, increased renin-angiotensin-aldosterone system, normal blood pressure, resistance to the pressor effects of angiotensin II and juxtaglomerular cell hyperplas …
Bartter's Syndrome is characterized by renal potassium wasting with hypokalemia, metabolic alkalosis, increased renin-a …
Life-threatening hypokalemia in an asthmatic patient treated with high-dose hydrocortisone.
Tsai WS, Wu CP, Hsu YJ, Lin SH. Tsai WS, et al. Am J Med Sci. 2004 Mar;327(3):152-5. doi: 10.1097/00000441-200403000-00007. Am J Med Sci. 2004. PMID: 15090754
Hypokalemia was profound, with plasma potassium (K+) concentration of 1.7 mEq/L, and associated with renal potassium wasting, as evidenced by a transtubular potassium concentration gradient of 12; metabolic alkalosis (plasma HCO3-, 37 mEq/L) was also present. …
Hypokalemia was profound, with plasma potassium (K+) concentration of 1.7 mEq/L, and associated with renal potassium wastin …
Novel mutation in the SLC12A3 gene in a Sri Lankan family with Gitelman syndrome & coexistent diabetes: a case report.
Subasinghe CJ, Sirisena ND, Herath C, Berge KE, Leren TP, Bulugahapitiya U, Dissanayake VHW. Subasinghe CJ, et al. BMC Nephrol. 2017 Apr 26;18(1):140. doi: 10.1186/s12882-017-0563-0. BMC Nephrol. 2017. PMID: 28446151 Free PMC article.
CASE PRESENTATION: In this report, we describe two siblings from a Sri Lankan non-consanguineous family presenting with hypokalaemia associated with renal potassium wasting, hypomagnesemia, hypocalciuria and hypereninemic hyperaldosteronism with normal blood …
CASE PRESENTATION: In this report, we describe two siblings from a Sri Lankan non-consanguineous family presenting with hypokalaemia associa …