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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1997 1
1999 1
2001 1
2002 1
2003 1
2004 1
2005 2
2007 2
2009 4
2010 2
2011 1
2012 3
2013 2
2014 4
2015 1
2017 1
2019 5
2020 2
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40 results

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Quoted phrase not found in phrase index: "Rhabdomyolysis, susceptibility to, 1"
Page 1
Influenza virus-related critical illness: pathophysiology and epidemiology.
Kalil AC, Thomas PG. Kalil AC, et al. Crit Care. 2019 Jul 19;23(1):258. doi: 10.1186/s13054-019-2539-x. Crit Care. 2019. PMID: 31324202 Free PMC article. Review.
In humans, the respiratory epithelium is the only site where the hemagglutinin (HA) molecule is effectively cleaved, generating infectious virus particles. Virus transmission occurs through a susceptible individual's contact with aerosols or respiratory fomites from an inf …
In humans, the respiratory epithelium is the only site where the hemagglutinin (HA) molecule is effectively cleaved, generating infectious v …
Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update.
Schachter M. Schachter M. Fundam Clin Pharmacol. 2005 Feb;19(1):117-25. doi: 10.1111/j.1472-8206.2004.00299.x. Fundam Clin Pharmacol. 2005. PMID: 15660968 Review.
Lovastatin, pravastatin and simvastatin are derived from fungal metabolites and have elimination half-lives of 1-3 h. Atorvastatin, cerivastatin (withdrawn from clinical use in 2001), fluvastatin, pitavastatin and rosuvastatin are fully synthetic compounds, with eli …
Lovastatin, pravastatin and simvastatin are derived from fungal metabolites and have elimination half-lives of 1-3 h. Atorvastatin, c …
Statins, myalgia, and rhabdomyolysis.
Tournadre A. Tournadre A. Joint Bone Spine. 2020 Jan;87(1):37-42. doi: 10.1016/j.jbspin.2019.01.018. Epub 2019 Feb 6. Joint Bone Spine. 2020. PMID: 30735805
Statin-associated muscle symptoms (SAMSs) vary considerably in frequency and severity, with a spectrum extending from myalgia with normal creatine kinase (CK) levels or asymptomatic hyperCKemia to potentially life-threatening rhabdomyolysis and necrotizing autoimmune myopa …
Statin-associated muscle symptoms (SAMSs) vary considerably in frequency and severity, with a spectrum extending from myalgia with normal cr …
Malignant hyperthermia.
Rosenberg H, Davis M, James D, Pollock N, Stowell K. Rosenberg H, et al. Orphanet J Rare Dis. 2007 Apr 24;2:21. doi: 10.1186/1750-1172-2-21. Orphanet J Rare Dis. 2007. PMID: 17456235 Free PMC article. Review.
Due to ATP depletion, the muscle membrane integrity is compromised leading to hyperkalemia and rhabdomyolysis. In most cases, the syndrome is caused by a defect in the ryanodine receptor. Over 90 mutations have been identified in the RYR-1 gene located on chromosome …
Due to ATP depletion, the muscle membrane integrity is compromised leading to hyperkalemia and rhabdomyolysis. In most cases, the syn …
The role of mitochondria in statin-induced myopathy.
Apostolopoulou M, Corsini A, Roden M. Apostolopoulou M, et al. Eur J Clin Invest. 2015 Jul;45(7):745-54. doi: 10.1111/eci.12461. Epub 2015 Jun 15. Eur J Clin Invest. 2015. PMID: 25991405 Free article. Review.
Carriers for carnitine palmitoyltransferase II deficiency and McArdle disease also present with higher prevalence of statin-induced myopathy. CONCLUSIONS: Despite the widespread use of statins, the pathogenesis of statin-induced myopathy remains unclear, requiring prospect …
Carriers for carnitine palmitoyltransferase II deficiency and McArdle disease also present with higher prevalence of statin-induced m …
Non-cardiovascular effects associated with statins.
Desai CS, Martin SS, Blumenthal RS. Desai CS, et al. BMJ. 2014 Jul 17;349:g3743. doi: 10.1136/bmj.g3743. BMJ. 2014. PMID: 25035309 Free PMC article. Review.
Statins form the pharmacologic cornerstone of the primary and secondary prevention of atherosclerotic cardiovascular disease. In addition to beneficial cardiovascular effects, statins seem to have multiple non-cardiovascular effects. ...Severe myopathy (rhabdomyolysis …
Statins form the pharmacologic cornerstone of the primary and secondary prevention of atherosclerotic cardiovascular disease. In addi …
Statin myotoxicity: a review of genetic susceptibility factors.
Needham M, Mastaglia FL. Needham M, et al. Neuromuscul Disord. 2014 Jan;24(1):4-15. doi: 10.1016/j.nmd.2013.09.011. Epub 2013 Sep 30. Neuromuscul Disord. 2014. PMID: 24176465 Review.
One of the major factors contributing to intolerance and non-compliance are the muscle side-effects, which range from mild myalgia through to severe life-threatening rhabdomyolysis. One way to address this is pharmacogenomic screening, which aims to individualize therapy t …
One of the major factors contributing to intolerance and non-compliance are the muscle side-effects, which range from mild myalgia through t …
Pharmacological comparison of the statins.
Klotz U. Klotz U. Arzneimittelforschung. 2003;53(9):605-11. doi: 10.1055/s-0031-1297156. Arzneimittelforschung. 2003. PMID: 14558433 Review.
Clinical outcome data indicate that for simvastatin the lowest number of treated patients is needed to prevent one major coronary event (NNT 15). ...Moreover, coadministration of gemfibrozil should be avoided because it seems to increase the very low risk for statin-induce …
Clinical outcome data indicate that for simvastatin the lowest number of treated patients is needed to prevent one major coronary eve …
The genetics of statin-induced myopathy.
Ghatak A, Faheem O, Thompson PD. Ghatak A, et al. Atherosclerosis. 2010 Jun;210(2):337-43. doi: 10.1016/j.atherosclerosis.2009.11.033. Epub 2009 Nov 27. Atherosclerosis. 2010. PMID: 20042189 Review.
BACKGROUND: Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are usually well tolerated medications, but muscle symptoms, ranging from mild myalgia to clinically important rhabdomyolysis are an important side effect of these drugs and a leading cause of …
BACKGROUND: Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are usually well tolerated medications, but muscle symptoms …
Statin-associated myopathy: from genetic predisposition to clinical management.
Vrablik M, Zlatohlavek L, Stulc T, Adamkova V, Prusikova M, Schwarzova L, Hubacek JA, Ceska R. Vrablik M, et al. Physiol Res. 2014;63(Suppl 3):S327-34. doi: 10.33549/physiolres.932865. Physiol Res. 2014. PMID: 25428737 Free article. Review.
Statin-associated myopathy (SAM) represents a broad spectrum of disorders from insignificant myalgia to fatal rhabdomyolysis. Its frequency ranges from 1-5 % in clinical trials to 15-20 % in everyday clinical practice. ...Thus, we propose a scoring sys …
Statin-associated myopathy (SAM) represents a broad spectrum of disorders from insignificant myalgia to fatal rhabdomyolysis. Its fre …
40 results