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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1956 1
1958 1
1961 1
1962 2
1964 1
1966 1
1969 2
1971 2
1972 3
1973 3
1975 9
1976 17
1977 9
1978 11
1979 12
1980 22
1981 18
1982 18
1983 25
1984 21
1985 29
1986 31
1987 33
1988 29
1989 33
1990 50
1991 53
1992 57
1993 49
1994 47
1995 57
1996 52
1997 66
1998 71
1999 67
2000 78
2001 73
2002 81
2003 98
2004 94
2005 93
2006 108
2007 100
2008 125
2009 107
2010 141
2011 162
2012 122
2013 136
2014 152
2015 151
2016 165
2017 179
2018 164
2019 167
2020 180
2021 164
2022 182
2023 160
2024 76

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3,732 results

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Page 1
Biomarkers of Parkinson's disease: present and future.
Miller DB, O'Callaghan JP. Miller DB, et al. Metabolism. 2015 Mar;64(3 Suppl 1):S40-6. doi: 10.1016/j.metabol.2014.10.030. Epub 2014 Oct 31. Metabolism. 2015. PMID: 25510818 Free PMC article. Review.
The onset of molecular and cellular neuropathology of PD likely occurs decades before the onset of the motor symptoms characteristic of PD. The hallmark symptoms of PD, resting tremors, rigidity and postural disabilities, are related to dopamine (DA) deficiency. ...In the …
The onset of molecular and cellular neuropathology of PD likely occurs decades before the onset of the motor symptoms characteristic of PD. …
Surrogates for rigidity and PIGD MDS-UPDRS subscores using wearable sensors.
Safarpour D, Dale ML, Shah VV, Talman L, Carlson-Kuhta P, Horak FB, Mancini M. Safarpour D, et al. Gait Posture. 2022 Jan;91:186-191. doi: 10.1016/j.gaitpost.2021.10.029. Epub 2021 Oct 26. Gait Posture. 2022. PMID: 34736096 Free PMC article.
The multivariable linear regression showed that rigidity subscore was best predicted by the number of walking bouts while the PIGD subscore was best predicted by a combination of number of walking bouts, gait speed, and postural sway. SIGNIFICANCE: The correl …
The multivariable linear regression showed that rigidity subscore was best predicted by the number of walking bouts while the …
Rigidity in Parkinson's disease: evidence from biomechanical and neurophysiological measures.
Asci F, Falletti M, Zampogna A, Patera M, Hallett M, Rothwell J, Suppa A. Asci F, et al. Brain. 2023 Sep 1;146(9):3705-3718. doi: 10.1093/brain/awad114. Brain. 2023. PMID: 37018058 Free PMC article.
Lastly, specific biomechanical and neurophysiological abnormalities correlated with the clinical score of rigidity. 'Objective rigidity' in PD correlates with velocity-dependent abnormal neuronal activity. The observations overall (i.e. the velocity-de …
Lastly, specific biomechanical and neurophysiological abnormalities correlated with the clinical score of rigidity. 'Objective …
Zonisamide add-on in tremor-dominant Parkinson's disease- A randomized controlled clinical trial.
Pillai KS, Bhat P, Srivastava AK, Rajan R, Radhakrishnan DM, Elavarasi A, Srivastava MP, Singh MB, Vishnu VY, Prasad K, Pandit AK, Goyal V. Pillai KS, et al. Parkinsonism Relat Disord. 2022 Dec;105:1-6. doi: 10.1016/j.parkreldis.2022.10.017. Epub 2022 Oct 25. Parkinsonism Relat Disord. 2022. PMID: 36323130 Clinical Trial.
Percentage change from baseline in the UPDRS tremor score was the primary outcome whereas percentage change from baseline of total UPDRS score, UPDRS rigidity and bradykinesia scores, TETRAS score, and accelerometric tremor analysis values were …
Percentage change from baseline in the UPDRS tremor score was the primary outcome whereas percentage change from baseline of total UP …
Plasma Extracellular Vesicle α-Synuclein Level in Patients with Parkinson's Disease.
Chung CC, Chan L, Chen JH, Hung YC, Hong CT. Chung CC, et al. Biomolecules. 2021 May 17;11(5):744. doi: 10.3390/biom11050744. Biomolecules. 2021. PMID: 34067663 Free PMC article.
Plasma EV alpha-synuclein levels in the patients with PD did not correlate with age, disease duration, Part I and II scores of the Unified Parkinson's Disease Rating Scale (UPDRS), or the Mini-Mental State Examination scores. However, such levels were significantly …
Plasma EV alpha-synuclein levels in the patients with PD did not correlate with age, disease duration, Part I and II scores of the Un …
Levodopa responsiveness in Parkinson's disease: harnessing real-life experience with machine-learning analysis.
Djaldetti R, Hadad B, Reiner J, Kharash BA, Lerner B. Djaldetti R, et al. J Neural Transm (Vienna). 2022 Oct;129(10):1289-1297. doi: 10.1007/s00702-022-02540-2. Epub 2022 Aug 27. J Neural Transm (Vienna). 2022. PMID: 36030311
Regression and machine-learning analyses were used to determine factors that are associated with levodopa responsiveness and might identify patients who will benefit from treatment. The UPDRS-III score improved by 30% (good response) in 128 patients (43%). On regression an …
Regression and machine-learning analyses were used to determine factors that are associated with levodopa responsiveness and might identify …
Meta-analysis of the clinical and laboratory diagnosis of appendicitis.
Andersson RE. Andersson RE. Br J Surg. 2004 Jan;91(1):28-37. doi: 10.1002/bjs.4464. Br J Surg. 2004. PMID: 14716790 Review.
RESULTS: Inflammatory response variables (granulocyte count, proportion of polymorphonuclear blood cells, white blood cell count and C-reactive protein concentration), descriptors of peritoneal irritation (rebound and percussion tenderness, guarding and rigidity) and migra …
RESULTS: Inflammatory response variables (granulocyte count, proportion of polymorphonuclear blood cells, white blood cell count and C-react …
Clinical features and related factors of freezing of gait in patients with Parkinson's disease.
Zhang F, Shi J, Duan Y, Cheng J, Li H, Xuan T, Lv Y, Wang P, Li H. Zhang F, et al. Brain Behav. 2021 Nov;11(11):e2359. doi: 10.1002/brb3.2359. Epub 2021 Sep 22. Brain Behav. 2021. PMID: 34551452 Free PMC article.

The binary logistic regression analysis showed that the higher H-Y stage, higher rigidity subscore and Unified Parkinson's Disease Rating Scale II (UPDRS II) score, and UPDRS III score were significantly correlated with the occurrence of FOG (p < .05). ...

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The binary logistic regression analysis showed that the higher H-Y stage, higher rigidity subscore and Unified Parkinson's Disease Ra …
Characterization and localization of upper and lower extremity motor improvements in STN DBS for Parkinson's disease.
Askari A, Zhu BJ, Lyu X, Chou KL, Patil PG. Askari A, et al. Parkinsonism Relat Disord. 2022 Jan;94:84-88. doi: 10.1016/j.parkreldis.2021.11.036. Epub 2021 Dec 2. Parkinsonism Relat Disord. 2022. PMID: 34896928

RESULTS: In our study population (n = 78 patients), STN DBS improved all cardinal motor signs (beta = 0.64, p < .05). Improvement magnitudes were tremor > rigidity > bradykinesia. Effects of STN DBS on UE versus LE signs were statistically equal for tremor and bra

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RESULTS: In our study population (n = 78 patients), STN DBS improved all cardinal motor signs (beta = 0.64, p < .05). Improvement magnitu

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Rear Tip Extenders and Penile Prosthesis Rigidity: A Laboratory Study of Coloplast Prostheses.
Thirumavalavan N, Cordon BH, Gross MS, Taylor J, Eid JF. Thirumavalavan N, et al. J Sex Med. 2018 Jul;15(7):1030-1033. doi: 10.1016/j.jsxm.2018.05.001. Epub 2018 Jun 5. J Sex Med. 2018. PMID: 29884443 Free PMC article.
RESULTS: Increasing the length of RTEs increased the deflection in our model, indicative of decreased axial rigidity. CLINICAL TRANSLATIONS: The current work implies that having additional RTEs may decrease penile rigidity and in turn, patient satisfaction. STRENGTH …
RESULTS: Increasing the length of RTEs increased the deflection in our model, indicative of decreased axial rigidity. CLINICAL TRANSL …
3,732 results