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Secnidazole.
[No authors listed] [No authors listed] 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999997 Free Books & Documents. Review.
No information is available on the clinical use of secnidazole during breastfeeding and no studies have evaluated adverse effects of secnidazole on the infant during breastfeeding, but presumably they are similar to those of the closely related drug, metronidazole, …
No information is available on the clinical use of secnidazole during breastfeeding and no studies have evaluated adverse effects of …
Secnidazole.
[No authors listed] [No authors listed] 2020 Feb 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2020 Feb 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643547 Free Books & Documents. Review.
Secnidazole is an orally available, broad spectrum antimicrobial agent used in the treatment of bacterial vaginosis. Secnidazole is a nitroimidazole similar to metronidazole but is used as a single dose and, unlike metronidazole, has not been linked to serum enzyme …
Secnidazole is an orally available, broad spectrum antimicrobial agent used in the treatment of bacterial vaginosis. Secnidazole …
Secnidazole for Trichomoniasis in Women and Men.
Muzny CA, Van Gerwen OT. Muzny CA, et al. Sex Med Rev. 2022 Apr;10(2):255-262. doi: 10.1016/j.sxmr.2021.12.004. Epub 2022 Feb 10. Sex Med Rev. 2022. PMID: 35153156 Free PMC article. Review.
INTRODUCTION: Secnidazole (SEC), newly FDA-approved for trichomoniasis, is a potent 5-nitroimidazole with selective toxicity against various infections. ...METHODS: We conducted a search to identify existing research on SEC and trichomoniasis. On August 6, 2021, we searche …
INTRODUCTION: Secnidazole (SEC), newly FDA-approved for trichomoniasis, is a potent 5-nitroimidazole with selective toxicity against …
Secnidazole for treatment of bacterial vaginosis: a systematic review.
Abd El Aziz MA, Sharifipour F, Abedi P, Jahanfar S, Judge HM. Abd El Aziz MA, et al. BMC Womens Health. 2019 Oct 21;19(1):121. doi: 10.1186/s12905-019-0822-2. BMC Womens Health. 2019. PMID: 31638955 Free PMC article.
CONCLUSION: This review showed that 2 g and 1 g secnidazole were better than placebo, however, 2 g secnidazole was more effective than 1 g. Secnidazole 2 g was not different from metronidazole (500 mg bid for 5 days), or from secnidazole plus vaginal m …
CONCLUSION: This review showed that 2 g and 1 g secnidazole were better than placebo, however, 2 g secnidazole was more effect …
Secnidazole: a treatment for trichomoniasis in adolescents and adults.
Muzny CA, Van Gerwen OT, Legendre D. Muzny CA, et al. Expert Rev Anti Infect Ther. 2022 Aug;20(8):1067-1076. doi: 10.1080/14787210.2022.2080656. Epub 2022 Jun 8. Expert Rev Anti Infect Ther. 2022. PMID: 35642509 Free PMC article.
INTRODUCTION: Single-dose 2-g oral secnidazole (SEC), newly approved by the U.S. Food and Drug administration (FDA) for treatment of trichomoniasis, is a potent 5-nitroimidazole with selective toxicity against various micro-organisms. ...
INTRODUCTION: Single-dose 2-g oral secnidazole (SEC), newly approved by the U.S. Food and Drug administration (FDA) for treatment of …
Secnidazole (Solosec) for Bacterial Vaginosis.
Leggit JC, Saguil A. Leggit JC, et al. Am Fam Physician. 2019 Aug 15;100(4):242-243. Am Fam Physician. 2019. PMID: 31414782 Free article. No abstract available.
Secnidazole Is a Promising Imidazole Mitigator of Serratia marcescens Virulence.
Khayyat AN, Abbas HA, Khayat MT, Shaldam MA, Askoura M, Asfour HZ, Khafagy ES, Abu Lila AS, Allam AN, Hegazy WAH. Khayyat AN, et al. Microorganisms. 2021 Nov 11;9(11):2333. doi: 10.3390/microorganisms9112333. Microorganisms. 2021. PMID: 34835458 Free PMC article.
Secnidazole's protective activity against S. marcescens pathogenesis was assessed in vivo in mice. ...In conclusion, secnidazole is a promising anti-virulence agent that may be used to control infections caused by S. marcescens....
Secnidazole's protective activity against S. marcescens pathogenesis was assessed in vivo in mice. ...In conclusion, secnidazole …
Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis.
Gillis JC, Wiseman LR. Gillis JC, et al. Drugs. 1996 Apr;51(4):621-38. doi: 10.2165/00003495-199651040-00007. Drugs. 1996. PMID: 8706597 Review.
Secnidazole is structurally related to the commonly used 5-nitroimidazoles metronidazole and tinidazole. ...After administration of a single dose of secnidazole, parasitological eradication was achieved in approximately 92 to 100% of patients with urogenital trichom …
Secnidazole is structurally related to the commonly used 5-nitroimidazoles metronidazole and tinidazole. ...After administration of a …
Biology-oriented drug synthesis and evaluation of secnidazole esters as novel enzyme inhibitors.
Ansari MA, Saad SM, Khan KM, Salar U, Taslimi P, Taskın-Tok T, Saleem F, Jahangir S. Ansari MA, et al. Arch Pharm (Weinheim). 2022 Feb;355(2):e2100376. doi: 10.1002/ardp.202100376. Epub 2021 Dec 3. Arch Pharm (Weinheim). 2022. PMID: 34862640
The identification of novel compounds that can inhibit physiologically and metabolically important drug targets or enzymes has prime importance in medicinal chemistry. With this aim, a range of secnidazole esters 1-30 were synthesized under the heading of biology-oriented …
The identification of novel compounds that can inhibit physiologically and metabolically important drug targets or enzymes has prime importa …
214 results