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Multiple osteochondromas.
Bovée JV. Bovée JV. Orphanet J Rare Dis. 2008 Feb 13;3:3. doi: 10.1186/1750-1172-3-3. Orphanet J Rare Dis. 2008. PMID: 18271966 Free PMC article. Review.
The most important complication is malignant transformation of osteochondroma towards secondary peripheral chondrosarcoma, which is estimated to occur in 0.5-5%. ...For secondary peripheral chondrosarcoma, en-bloc resection of the lesion …
The most important complication is malignant transformation of osteochondroma towards secondary peripheral chondrosarcoma …
Diagnosis and prognosis of chondrosarcoma of bone.
Rozeman LB, Hogendoorn PC, Bovée JV. Rozeman LB, et al. Expert Rev Mol Diagn. 2002 Sep;2(5):461-72. doi: 10.1586/14737159.2.5.461. Expert Rev Mol Diagn. 2002. PMID: 12271817 Review.
Bcl-2 is a good diagnostic marker that can be used in the distinction between osteochondroma and low-grade secondary peripheral chondrosarcoma. For the prognosis of chondrosarcomas, the best and most commonly used marker at present is histological grade. ...
Bcl-2 is a good diagnostic marker that can be used in the distinction between osteochondroma and low-grade secondary peripheral …
Secondary peripheral chondrosarcoma in multiple osteochondromas: a retrospective single-institution case series.
Gnoli M, Gambarotti M, Righi A, Staals EL, Evangelista A, Tremosini M, Brizola E, Mordenti M, Boarini M, Locatelli M, Pedrini E, Sangiorgi L. Gnoli M, et al. Orphanet J Rare Dis. 2024 Feb 13;19(1):63. doi: 10.1186/s13023-023-03006-8. Orphanet J Rare Dis. 2024. PMID: 38351015 Free PMC article.
BACKGROUND: Multiple osteochondromas is genetic disorder characterized by the formation of multiple benign cartilage-capped bone tumors, named osteochondromas, during skeletal development. The most feared complication is the secondary peripheral chondrosarcoma …
BACKGROUND: Multiple osteochondromas is genetic disorder characterized by the formation of multiple benign cartilage-capped bone tumors, nam …
An unusual diagnosis for an usual test.
Trombetta A, Migliarino V, Faletra F, Barbi E, Tornese G. Trombetta A, et al. Ital J Pediatr. 2020 Jun 10;46(1):81. doi: 10.1186/s13052-020-00846-z. Ital J Pediatr. 2020. PMID: 32522262 Free PMC article.
Moreover, multiple complications may arise due to the presence of osteochondromas, including tendon and compression muscle pain, neurovascular disorders, obstetric problems, scoliosis and malignant transformation into secondary peripheral chondrosarcoma in ad …
Moreover, multiple complications may arise due to the presence of osteochondromas, including tendon and compression muscle pain, neurovascul …
Interobserver reliability in the histopathological diagnosis of cartilaginous tumors in patients with multiple osteochondromas.
de Andrea CE, Kroon HM, Wolterbeek R, Romeo S, Rosenberg AE, De Young BR, Liegl B, Inwards CY, Hauben E, McCarthy EF, Idoate M, Athanasou NA, Jones KB, Hogendoorn PC, Bovée JV. de Andrea CE, et al. Mod Pathol. 2012 Sep;25(9):1275-83. doi: 10.1038/modpathol.2012.78. Epub 2012 May 4. Mod Pathol. 2012. PMID: 22555180 Free PMC article.
The aim of this study was to investigate interobserver reliability in histological diagnosis of cartilaginous tumors in the setting of multiple osteochondromas and to evaluate possible histological parameters that could differentiate among osteochondroma, low- and high-grade s …
The aim of this study was to investigate interobserver reliability in histological diagnosis of cartilaginous tumors in the setting of multi …
Intraosseous atypical chondroid tumor or chondrosarcoma grade 1 in patients with multiple osteochondromas.
Goud AL, Wuyts W, Bessems J, Bramer J, van der Woude HJ, Ham J. Goud AL, et al. J Bone Joint Surg Am. 2015 Jan 7;97(1):24-31. doi: 10.2106/JBJS.N.00121. J Bone Joint Surg Am. 2015. PMID: 25568391
BACKGROUND: The autosomal dominant condition multiple osteochondromas, formerly called multiple hereditary exostoses, is associated with a risk of malignant progression of osteochondroma into secondary peripheral chondrosarcoma. Most patients with multiple os …
BACKGROUND: The autosomal dominant condition multiple osteochondromas, formerly called multiple hereditary exostoses, is associated with a r …
The use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting.
Hameetman L, Kok P, Eilers PH, Cleton-Jansen AM, Hogendoorn PC, Bovée JV. Hameetman L, et al. Virchows Arch. 2005 Apr;446(4):430-7. doi: 10.1007/s00428-005-1208-4. Epub 2005 Mar 3. Virchows Arch. 2005. PMID: 15744499
Distinguishing osteochondroma from low-grade secondary peripheral chondrosarcoma can be difficult. In osteochondroma, growth-signalling pathways are thought to be downregulated through exostosin (EXT) inactivation. ...
Distinguishing osteochondroma from low-grade secondary peripheral chondrosarcoma can be difficult. In osteochondroma, g …
Cytogenetic analysis of a low-grade secondary peripheral chondrosarcoma arising in synovial chondromatosis.
Kyriazoglou AI, Rizou H, Dimitriadis E, Arnogiannaki N, Agnantis N, Pandis N. Kyriazoglou AI, et al. In Vivo. 2013 Jan-Feb;27(1):57-60. In Vivo. 2013. PMID: 23239852
We present the case of a 54-year-old male with the diagnosis of low-grade secondary peripheral chondrosarcoma developed in the context of synovial chondromatosis. ...
We present the case of a 54-year-old male with the diagnosis of low-grade secondary peripheral chondrosarcoma developed …