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Quoted phrase not found in phrase index: "Secondary Peripheral Chondrosarcoma, Grade 2"
Page 1
Secondary peripheral chondrosarcoma in multiple osteochondromas: a retrospective single-institution case series.
Gnoli M, Gambarotti M, Righi A, Staals EL, Evangelista A, Tremosini M, Brizola E, Mordenti M, Boarini M, Locatelli M, Pedrini E, Sangiorgi L. Gnoli M, et al. Orphanet J Rare Dis. 2024 Feb 13;19(1):63. doi: 10.1186/s13023-023-03006-8. Orphanet J Rare Dis. 2024. PMID: 38351015 Free PMC article.
BACKGROUND: Multiple osteochondromas is genetic disorder characterized by the formation of multiple benign cartilage-capped bone tumors, named osteochondromas, during skeletal development. The most feared complication is the secondary peripheral chondrosarcoma …
BACKGROUND: Multiple osteochondromas is genetic disorder characterized by the formation of multiple benign cartilage-capped bone tumors, nam …
Diagnosis and prognosis of chondrosarcoma of bone.
Rozeman LB, Hogendoorn PC, Bovée JV. Rozeman LB, et al. Expert Rev Mol Diagn. 2002 Sep;2(5):461-72. doi: 10.1586/14737159.2.5.461. Expert Rev Mol Diagn. 2002. PMID: 12271817 Review.
In this review, the conventional chondrosarcomas are subdivided into central and secondary peripheral chondrosarcomas, based on their different genetic and clinicopathological background. ...Bcl-2 is a good diagnostic marker that can be used in the dis …
In this review, the conventional chondrosarcomas are subdivided into central and secondary peripheral chondrosarcoma …
Paediatric chondrosarcomas: a retrospective review of 17 cases.
Gambarotti M, Righi A, Picci P, Bertoni F, Manfrini M, Donati DM, Dei Tos AP, Vanel D. Gambarotti M, et al. Histopathology. 2016 Jun;68(7):1073-8. doi: 10.1111/his.12881. Epub 2015 Nov 25. Histopathology. 2016. PMID: 26408960
AIMS: Chondrosarcoma is primarily a tumour of adulthood and old age. Some studies indicate that survival is worse in paediatric than in adult chondrosarcomas. ...Seventeen patients with central (10), peripheral (five) and periosteal (two) chondrosarcoma …
AIMS: Chondrosarcoma is primarily a tumour of adulthood and old age. Some studies indicate that survival is worse in paediatric than …
Pelvic chondrosarcomas: surgical treatment options.
Deloin X, Dumaine V, Biau D, Karoubi M, Babinet A, Tomeno B, Anract P. Deloin X, et al. Orthop Traumatol Surg Res. 2009 Oct;95(6):393-401. doi: 10.1016/j.otsr.2009.05.004. Epub 2009 Oct 3. Orthop Traumatol Surg Res. 2009. PMID: 19801212 Free article.
The average follow-up duration was 94 months. Eleven patients had a grade 1 chondrosarcoma, 36 a grade 2 chondrosarcoma, five were grade 3, and seven were dedifferentiated chondrosarcoma. ...However, resection guaranteed a better function …
The average follow-up duration was 94 months. Eleven patients had a grade 1 chondrosarcoma, 36 a grade 2 chondrosarc …
The diagnostic significance of pulmonary nodules on CT thorax in chondrosarcoma of bone.
McLoughlin E, Davies AM, Iqbal A, James SL, Botchu R. McLoughlin E, et al. Clin Radiol. 2020 May;75(5):395.e7-395.e16. doi: 10.1016/j.crad.2019.11.017. Epub 2019 Dec 31. Clin Radiol. 2020. PMID: 31898960
Patients with grade 3 and dedifferentiated chondrosarcoma were more likely to have pulmonary metastases than patients with grade 1/2 chondrosarcoma. The time interval to developing metastases was shorter in patients with grade 2/3 and dedifferen …
Patients with grade 3 and dedifferentiated chondrosarcoma were more likely to have pulmonary metastases than patients with …
Chondrosarcoma in Norway 1990-2013; an epidemiological and prognostic observational study of a complete national cohort.
Thorkildsen J, Taksdal I, Bjerkehagen B, Haugland HK, Børge Johannesen T, Viset T, Norum OJ, Bruland Ø, Zaikova O. Thorkildsen J, et al. Acta Oncol. 2019 Mar;58(3):273-282. doi: 10.1080/0284186X.2018.1554260. Epub 2019 Jan 11. Acta Oncol. 2019. PMID: 30632866
Malignancy grade 3 independently predicts rate of metastasis and presence of soft tissue component predicts local recurrence, metastasis and survival. ...Malignancy grade 3 and the presence of a soft tissue component independently pred …
Malignancy grade 3 independently predicts rate of metastasis and presence of soft tissue component predicts loca …
Dedifferentiated peripheral chondrosarcomas: regulation of EXT-downstream molecules and differentiation-related genes.
Rozeman LB, de Bruijn IH, Bacchini P, Staals EL, Bertoni F, Bovée JV, Hogendoorn PC. Rozeman LB, et al. Mod Pathol. 2009 Nov;22(11):1489-98. doi: 10.1038/modpathol.2009.120. Epub 2009 Sep 4. Mod Pathol. 2009. PMID: 19734846 Free article.
Interestingly, although the chondrogenic component of dedifferentiated peripheral chondrosarcoma is CD44+/CD44v3-, secondary peripheral chondrosarcomas is CD44-/CD44v3+, which suggest different splicing (preference). The prognostic value …
Interestingly, although the chondrogenic component of dedifferentiated peripheral chondrosarcoma is CD44+/CD44v3-, secondar …
The use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting.
Hameetman L, Kok P, Eilers PH, Cleton-Jansen AM, Hogendoorn PC, Bovée JV. Hameetman L, et al. Virchows Arch. 2005 Apr;446(4):430-7. doi: 10.1007/s00428-005-1208-4. Epub 2005 Mar 3. Virchows Arch. 2005. PMID: 15744499
Distinguishing osteochondroma from low-grade secondary peripheral chondrosarcoma can be difficult. In osteochondroma, growth-signalling pathways are thought to be downregulated through exostosin (EXT) inactivation. ...We investigated their use as diagn …
Distinguishing osteochondroma from low-grade secondary peripheral chondrosarcoma can be difficult. In osteochond …
Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours.
Boeuf S, Bovée JV, Lehner B, Hogendoorn PC, Richter W. Boeuf S, et al. Histopathology. 2010 Apr;56(5):641-51. doi: 10.1111/j.1365-2559.2010.03528.x. Histopathology. 2010. PMID: 20459575
Immunohistochemical analysis of galectin 1 and of further hypoxia-associated proteins was performed on 68 central and peripheral tumour samples. Hypoxia-inducible factor 1alpha (HIF-1alpha) activation was significantly elevated in high-grade central chondrosarcom …
Immunohistochemical analysis of galectin 1 and of further hypoxia-associated proteins was performed on 68 central and peripheral tumo …
Is the Width of a Surgical Margin Associated with the Outcome of Disease in Patients with Peripheral Chondrosarcoma of the Pelvis? A Multicenter Study.
Tsuda Y, Evans S, Stevenson JD, Parry M, Fujiwara T, Laitinen M, Outani H, Jeys L. Tsuda Y, et al. Clin Orthop Relat Res. 2019 Nov;477(11):2432-2440. doi: 10.1097/CORR.0000000000000926. Clin Orthop Relat Res. 2019. PMID: 31453886 Free PMC article.
Although current guidelines recommend resection of histologic Grade II or Grade III chondrosarcomas with a "wide" margin, there are no specific recommendations for the adequate width of a surgical margin. QUESTIONS/PURPOSES: (1) What is the disease-specific a …
Although current guidelines recommend resection of histologic Grade II or Grade III chondrosarcomas with a "wide" margi …
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