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Page 1
Dynamic Resting-State Network Biomarkers of Antidepressant Treatment Response.
Kaiser RH, Chase HW, Phillips ML, Deckersbach T, Parsey RV, Fava M, McGrath PJ, Weissman M, Oquendo MA, McInnis MG, Carmody T, Cooper CM, Trivedi MH, Pizzagalli DA. Kaiser RH, et al. Biol Psychiatry. 2022 Oct 1;92(7):533-542. doi: 10.1016/j.biopsych.2022.03.020. Epub 2022 Apr 6. Biol Psychiatry. 2022. PMID: 35680431 Free PMC article. Clinical Trial.
Multilevel modeling estimated the associations between pretreatment network dynamics and sertraline response and between early (pretreatment to 1 week) changes in network dynamics and sertraline response. RESULTS: Dynamic network markers of early se …
Multilevel modeling estimated the associations between pretreatment network dynamics and sertraline response and between early …
Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis.
Alhadab AA, Rhein J, Tugume L, Musubire A, Williams DA, Abassi M, Nicol MR, Meya DB, Boulware DR, Brundage RC; ASTRO-CM Study Team. Alhadab AA, et al. J Pharmacokinet Pharmacodyn. 2019 Dec;46(6):565-576. doi: 10.1007/s10928-019-09657-0. Epub 2019 Oct 4. J Pharmacokinet Pharmacodyn. 2019. PMID: 31584146 Free PMC article.
Adjunctive sertraline significantly increased CSF fungal clearance rate compared to COAT trial and sertraline effect was dose-independent with no covariate found to affect fungal clearance including ART. Study findings suggest sertraline response could be mediated b …
Adjunctive sertraline significantly increased CSF fungal clearance rate compared to COAT trial and sertraline effect was dose-independent wi …
Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population.
Bråten LS, Ingelman-Sundberg M, Jukic MM, Molden E, Kringen MK. Bråten LS, et al. Clin Transl Sci. 2022 Sep;15(9):2135-2145. doi: 10.1111/cts.13347. Epub 2022 Jun 22. Clin Transl Sci. 2022. PMID: 35668575 Free PMC article.
In the current study we have examined the role of a newly discovered ultrarapid CYP2C:TG haplotype and CYP2B6 variants in order to identify the possible missing heritability for such variation in sertraline response in a large patient population (n = 840). Compared …
In the current study we have examined the role of a newly discovered ultrarapid CYP2C:TG haplotype and CYP2B6 variants in order to identify …
Serotonin transporter genotype and function in relation to antidepressant response in Koreans.
Myung W, Lim SW, Kim S, Kim H, Chung JW, Seo MY, Kim JW, Carroll BJ, Kim DK. Myung W, et al. Psychopharmacology (Berl). 2013 Jan;225(2):283-90. doi: 10.1007/s00213-012-2813-y. Epub 2012 Aug 12. Psychopharmacology (Berl). 2013. PMID: 22885912
For statistical power, both samples were enriched with the l/l 5-HTTLPR polymorphism, which is uncommon in Koreans. Patients were treated with fluoxetine or sertraline. Response was assessed at 6 weeks. Subjects were genotyped for s/l polymorphism in the 5-HTT promo …
For statistical power, both samples were enriched with the l/l 5-HTTLPR polymorphism, which is uncommon in Koreans. Patients were treated wi …
Onset of major depression associated with acute coronary syndromes: relationship of onset, major depressive disorder history, and episode severity to sertraline benefit.
Glassman AH, Bigger JT, Gaffney M, Shapiro PA, Swenson JR. Glassman AH, et al. Arch Gen Psychiatry. 2006 Mar;63(3):283-8. doi: 10.1001/archpsyc.63.3.283. Arch Gen Psychiatry. 2006. PMID: 16520433 Clinical Trial.
Patients whose current episodes of MDD begin before ACS, those with a history of MDD, and those whose episodes are severe should be treated because they will benefit considerably from sertraline. Since these 3 predictors of sertraline response are independent, havin …
Patients whose current episodes of MDD begin before ACS, those with a history of MDD, and those whose episodes are severe should be treated …