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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
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1979 1
1980 1
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1982 2
1983 1
1984 5
1986 3
1987 6
1988 2
1989 5
1990 3
1991 5
1992 6
1993 6
1994 14
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1997 19
1998 17
1999 29
2000 25
2001 19
2002 27
2003 26
2004 30
2005 31
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2008 59
2009 59
2010 59
2011 70
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2013 74
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2023 105
2024 35

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1,576 results

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Quoted phrase not found in phrase index: "Shock From Lead"
Page 1
Sepsis-associated acute kidney injury-treatment standard.
Zarbock A, Koyner JL, Gomez H, Pickkers P, Forni L; Acute Disease Quality Initiative group. Zarbock A, et al. Nephrol Dial Transplant. 2023 Dec 20;39(1):26-35. doi: 10.1093/ndt/gfad142. Nephrol Dial Transplant. 2023. PMID: 37401137 Review.
Sepsis is a host's deleterious response to infection, which could lead to life-threatening organ dysfunction. Sepsis-associated acute kidney injury (SA-AKI) is the most frequent organ dysfunction and is associated with increased morbidity and mortality. ...We review the cu …
Sepsis is a host's deleterious response to infection, which could lead to life-threatening organ dysfunction. Sepsis-associated acute …
Gut-liver crosstalk in sepsis-induced liver injury.
Sun J, Zhang J, Wang X, Ji F, Ronco C, Tian J, Yin Y. Sun J, et al. Crit Care. 2020 Oct 19;24(1):614. doi: 10.1186/s13054-020-03327-1. Crit Care. 2020. PMID: 33076940 Free PMC article. Review.
Sepsis-induced liver injury is recognized as a powerful independent predictor of mortality in the intensive care unit. During systemic infections, the liver regulates immune defenses via bacterial clearance, production of acute-phase proteins (APPs) and cytokines, and meta …
Sepsis-induced liver injury is recognized as a powerful independent predictor of mortality in the intensive care unit. During systemi …
Sepsis and the microcirculation: the impact on outcomes.
Yajnik V, Maarouf R. Yajnik V, et al. Curr Opin Anaesthesiol. 2022 Apr 1;35(2):230-235. doi: 10.1097/ACO.0000000000001098. Curr Opin Anaesthesiol. 2022. PMID: 35081058 Review.
PURPOSE OF REVIEW: Advances in the treatment of septic shock have historically focused on resuscitation endpoints, mainly mean arterial pressure and cardiac output. ...Microcirculatory damage can be observed sublingually and appears to have prognostic value. SUMMARY …
PURPOSE OF REVIEW: Advances in the treatment of septic shock have historically focused on resuscitation endpoints, mainly mean arteri …
The pathophysiology of sepsis - 2021 update: Part 2, organ dysfunction and assessment.
Jacobi J. Jacobi J. Am J Health Syst Pharm. 2022 Mar 7;79(6):424-436. doi: 10.1093/ajhp/zxab393. Am J Health Syst Pharm. 2022. PMID: 34651652 Review.
In this article (part 2), major organ systems and their dysfunction in sepsis are reviewed, with discussion of scoring systems used to identify patterns and abnormal vital signs and laboratory values associated with sepsis. SUMMARY: Sepsis is a dysregulated host res …
In this article (part 2), major organ systems and their dysfunction in sepsis are reviewed, with discussion of scoring systems …
Cytokine release syndrome and cancer immunotherapies - historical challenges and promising futures.
Shah D, Soper B, Shopland L. Shah D, et al. Front Immunol. 2023 May 25;14:1190379. doi: 10.3389/fimmu.2023.1190379. eCollection 2023. Front Immunol. 2023. PMID: 37304291 Free PMC article. Review.
CRS is a phenomenon of immune hyperactivation that results in excessive cytokine secretion, and if left unchecked, it may lead to multi-organ failure and death. Here we review the pathophysiology of CRS, its occurrence and management in the context of cancer immunotherapy, …
CRS is a phenomenon of immune hyperactivation that results in excessive cytokine secretion, and if left unchecked, it may lead to mul …
The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update?
Moreno R, Rhodes A, Piquilloud L, Hernandez G, Takala J, Gershengorn HB, Tavares M, Coopersmith CM, Myatra SN, Singer M, Rezende E, Prescott HC, Soares M, Timsit JF, de Lange DW, Jung C, De Waele JJ, Martin GS, Summers C, Azoulay E, Fujii T, McLean AS, Vincent JL. Moreno R, et al. Crit Care. 2023 Jan 13;27(1):15. doi: 10.1186/s13054-022-04290-9. Crit Care. 2023. PMID: 36639780 Free PMC article. Review.
The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. ...By so doing, we hope to stimulate debate and discussion to move toward a new, p …
The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and …
Safety and clinical efficacy of BCMA CAR-T-cell therapy in multiple myeloma.
Roex G, Timmers M, Wouters K, Campillo-Davo D, Flumens D, Schroyens W, Chu Y, Berneman ZN, Lion E, Luo F, Anguille S. Roex G, et al. J Hematol Oncol. 2020 Dec 3;13(1):164. doi: 10.1186/s13045-020-01001-1. J Hematol Oncol. 2020. PMID: 33272302 Free PMC article.
RESULTS: Twenty-three different CAR-T-cell products have been used so far in 640 patients. Cytokine release syndrome was observed in 80.3% (69.0-88.2); 10.5% (6.8-16.0) had neurotoxicity. ...The results of this meta-analysis may assist the future design of CAR-T-cell studi …
RESULTS: Twenty-three different CAR-T-cell products have been used so far in 640 patients. Cytokine release syndrome was observed in …
Trial of early, goal-directed resuscitation for septic shock.
Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM; ProMISe Trial Investigators. Mouncey PR, et al. N Engl J Med. 2015 Apr 2;372(14):1301-11. doi: 10.1056/NEJMoa1500896. Epub 2015 Mar 17. N Engl J Med. 2015. PMID: 25776532 Free article. Clinical Trial.
BACKGROUND: Early, goal-directed therapy (EGDT) is recommended in international guidelines for the resuscitation of patients presenting with early septic shock. However, adoption has been limited, and uncertainty about its effectiveness remains. ...On average, EGDT increas …
BACKGROUND: Early, goal-directed therapy (EGDT) is recommended in international guidelines for the resuscitation of patients presenting with …
Effects of very early start of norepinephrine in patients with septic shock: a propensity score-based analysis.
Ospina-Tascón GA, Hernandez G, Alvarez I, Calderón-Tapia LE, Manzano-Nunez R, Sánchez-Ortiz AI, Quiñones E, Ruiz-Yucuma JE, Aldana JL, Teboul JL, Cavalcanti AB, De Backer D, Bakker J. Ospina-Tascón GA, et al. Crit Care. 2020 Feb 14;24(1):52. doi: 10.1186/s13054-020-2756-3. Crit Care. 2020. PMID: 32059682 Free PMC article. Clinical Trial.
BACKGROUND: Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fluids must be administered in advance. ...CONCLUSION: A very early start of vasopressor support seems to be safe, might limit the amount of f …
BACKGROUND: Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fl …
Norepinephrine vs Vasopressin: Which Vasopressor Should Be Discontinued First in Septic Shock? A Meta-Analysis.
Wu Z, Zhang S, Xu J, Xie J, Huang L, Huang Y, Yang Y, Qiu H. Wu Z, et al. Shock. 2020 Jan;53(1):50-57. doi: 10.1097/SHK.0000000000001345. Shock. 2020. PMID: 31008869
However, current guidelines do not advise clinicians as to which vasoactive agent to discontinue first once the patient's septic shock begins to resolve. Moreover, there is controversial data guiding clinicians on how to discontinue vasopressors for septic shock pat …
However, current guidelines do not advise clinicians as to which vasoactive agent to discontinue first once the patient's septic shock …
1,576 results