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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1943 1
1946 2
1947 2
1948 4
1949 6
1950 5
1951 10
1952 8
1953 7
1954 10
1955 7
1956 7
1957 14
1958 11
1959 5
1960 9
1961 7
1962 2
1963 7
1964 10
1965 9
1966 10
1967 14
1968 19
1969 18
1970 15
1971 30
1972 42
1973 45
1974 58
1975 50
1976 67
1977 70
1978 58
1979 68
1980 96
1981 96
1982 110
1983 103
1984 94
1985 127
1986 120
1987 147
1988 130
1989 161
1990 132
1991 163
1992 149
1993 197
1994 190
1995 159
1996 199
1997 223
1998 224
1999 216
2000 261
2001 291
2002 265
2003 317
2004 348
2005 356
2006 356
2007 413
2008 512
2009 477
2010 579
2011 663
2012 626
2013 680
2014 826
2015 851
2016 905
2017 909
2018 1026
2019 1107
2020 1328
2021 1381
2022 1352
2023 1392
2024 683

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19,559 results

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Page 1
Sickle Cell Disease: Monitoring, Current Treatment, and Therapeutics Under Development.
Hoppe C, Neumayr L. Hoppe C, et al. Hematol Oncol Clin North Am. 2019 Jun;33(3):355-371. doi: 10.1016/j.hoc.2019.01.014. Epub 2019 Mar 28. Hematol Oncol Clin North Am. 2019. PMID: 31030807 Review.
Screening and early detection of organ injury, as well as expanded use of red cell transfusion and hydroxyurea in children have changed best practices for clinical care in sickle cell disease. The current standard of care for children with sickle ce
Screening and early detection of organ injury, as well as expanded use of red cell transfusion and hydroxyurea in children have changed best …
Sickle Cell Disease and Its Respiratory Complications.
Khan MI, Patel N, Meda RT, Nuguru SP, Rachakonda S, Sripathi S. Khan MI, et al. Cureus. 2022 Aug 29;14(8):e28528. doi: 10.7759/cureus.28528. eCollection 2022 Aug. Cureus. 2022. PMID: 36185937 Free PMC article. Review.
Sickle cell disease (SCD) is a hematological disorder that is inherited in an autosomal recessive (AR) fashion. ...
Sickle cell disease (SCD) is a hematological disorder that is inherited in an autosomal recessive (AR) fashion. ...
Sickle Cell Disease: Advances in Treatment.
Gardner RV. Gardner RV. Ochsner J. 2018 Winter;18(4):377-389. doi: 10.31486/toj.18.0076. Ochsner J. 2018. PMID: 30559624 Free PMC article. Review.
BACKGROUND: Sickle cell disease causes significant morbidity and mortality and affects the economic and healthcare status of many countries. ...CONCLUSION: These examples demonstrate how the current knowledge of sickle cell disease pathop …
BACKGROUND: Sickle cell disease causes significant morbidity and mortality and affects the economic and healthcare stat …
Emerging disease-modifying therapies for sickle cell disease.
Carden MA, Little J. Carden MA, et al. Haematologica. 2019 Sep;104(9):1710-1719. doi: 10.3324/haematol.2018.207357. Epub 2019 Aug 14. Haematologica. 2019. PMID: 31413089 Free PMC article. Review.
Sickle cell disease afflicts millions of people worldwide and approximately 100,000 Americans. ...The National Heart, Lung, and Blood Institute's 2014 evidence-based guideline for sickle cell disease management states that additional rese
Sickle cell disease afflicts millions of people worldwide and approximately 100,000 Americans. ...The National Heart, L
Sickle cell disease: Clinical presentation and management of a global health challenge.
Houwing ME, de Pagter PJ, van Beers EJ, Biemond BJ, Rettenbacher E, Rijneveld AW, Schols EM, Philipsen JNJ, Tamminga RYJ, van Draat KF, Nur E, Cnossen MH; SCORE Consortium. Houwing ME, et al. Blood Rev. 2019 Sep;37:100580. doi: 10.1016/j.blre.2019.05.004. Epub 2019 May 20. Blood Rev. 2019. PMID: 31128863 Review.
Sickle cell disease is the most common monogenetic disease, with millions affected worldwide. ...Therapeutic options for sickle cell disease patients are however, still scarce. Predictors of sickle cell disease severi
Sickle cell disease is the most common monogenetic disease, with millions affected worldwide. ...Therapeutic options fo
L-glutamine for sickle cell disease: Knight or pawn?
Sadaf A, Quinn CT. Sadaf A, et al. Exp Biol Med (Maywood). 2020 Jan;245(2):146-154. doi: 10.1177/1535370219900637. Epub 2020 Jan 27. Exp Biol Med (Maywood). 2020. PMID: 31985279 Free PMC article. Review.
Oxidative stress is an important contributor to the pathophysiology of sickle cell disease. The pathways involved are complex and interlinked. ...However, the relative impact of L-glutamine on the redox environment in red blood cells in sickle cell
Oxidative stress is an important contributor to the pathophysiology of sickle cell disease. The pathways involved are c …
Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000-2021: a systematic analysis from the Global Burden of Disease Study 2021.
GBD 2021 Sickle Cell Disease Collaborators. GBD 2021 Sickle Cell Disease Collaborators. Lancet Haematol. 2023 Aug;10(8):e585-e599. doi: 10.1016/S2352-3026(23)00118-7. Epub 2023 Jun 15. Lancet Haematol. 2023. PMID: 37331373 Free PMC article.
In parallel, our goal was to estimate a more accurate account of sickle cell disease health burden using four types of epidemiological data on sickle cell disease: birth incidence, age-specific prevalence, with-condition mortality (total …
In parallel, our goal was to estimate a more accurate account of sickle cell disease health burden using four types of …
Nitric oxide and sickle cell disease-Is there a painful connection?
Hallmark L, Almeida LE, Kamimura S, Smith M, Quezado ZM. Hallmark L, et al. Exp Biol Med (Maywood). 2021 Feb;246(3):332-341. doi: 10.1177/1535370220976397. Epub 2020 Dec 6. Exp Biol Med (Maywood). 2021. PMID: 33517776 Free PMC article. Review.
Sickle cell disease is the most common hemoglobinopathy and affects millions worldwide. ...The large body of work demonstrating that hemolysis results in rapid consumption of the endogenous vasodilator nitric oxide, decreased nitric oxide production, and prom
Sickle cell disease is the most common hemoglobinopathy and affects millions worldwide. ...The large body of work demon
Sickle cell disease: an update.
Conway O'Brien E, Ali S, Chevassut T. Conway O'Brien E, et al. Clin Med (Lond). 2022 May;22(3):218-220. doi: 10.7861/clinmed.2022-0143. Clin Med (Lond). 2022. PMID: 35584832 Free PMC article.
Sickle cell disease is a common inherited disorder that is characterised by chronic haemolysis and vaso-occlusive episodes, resulting in severe pain and end-organ damage. The most frequent acute manifestation of sickle cell disease is a p
Sickle cell disease is a common inherited disorder that is characterised by chronic haemolysis and vaso-occlusive episo
[Lung manifestations of sickle-cell disease].
Hamzaoui A, Louhaichi S, Hamdi B. Hamzaoui A, et al. Rev Mal Respir. 2023 Jun;40(6):479-498. doi: 10.1016/j.rmr.2023.03.002. Epub 2023 Apr 12. Rev Mal Respir. 2023. PMID: 37059617 Review. French.
Sickle-cell disease is an autosomal recessive genetic disorder of hemoglobin that causes systemic damage. Hypoxia is the main actor of sickle-cell disease. It initiates acutely the pathogenic cascade leading to tissue damages that in turn
Sickle-cell disease is an autosomal recessive genetic disorder of hemoglobin that causes systemic damage. Hypoxia is th
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