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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1981 1
1985 2
1986 1
1991 1
1994 1
1995 1
1997 1
1998 1
2000 3
2001 1
2003 2
2004 1
2005 3
2006 5
2007 5
2008 3
2009 2
2010 3
2011 3
2013 8
2014 4
2015 4
2016 1
2017 3
2018 6
2019 6
2020 1
2021 4
2022 1
2023 5
2024 2

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76 results

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Page 1
Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery.
Atkin T, Comai S, Gobbi G. Atkin T, et al. Pharmacol Rev. 2018 Apr;70(2):197-245. doi: 10.1124/pr.117.014381. Pharmacol Rev. 2018. PMID: 29487083 Review.
There is evidence to recommend suvorexant and low-dose doxepin for sleep maintenance insomnia; there is also sufficient evidence to recommend ramelteon for sleep onset insomnia. Although there is limited evidence for the use of the quetiapine, trazodone, mirt …
There is evidence to recommend suvorexant and low-dose doxepin for sleep maintenance insomnia; there is also sufficient evidence to recommen …
The impact of stress on sleep: Pathogenic sleep reactivity as a vulnerability to insomnia and circadian disorders.
Kalmbach DA, Anderson JR, Drake CL. Kalmbach DA, et al. J Sleep Res. 2018 Dec;27(6):e12710. doi: 10.1111/jsr.12710. Epub 2018 May 24. J Sleep Res. 2018. PMID: 29797753 Free PMC article. Review.
Sleep reactivity is most pathologically and clinically pertinent when in excess, such that high sleep reactivity predicts risk for future insomnia disorder, with early evidence suggesting high sleep reactivity corresponds to severe insomnia phenotypes (sleep onset …
Sleep reactivity is most pathologically and clinically pertinent when in excess, such that high sleep reactivity predicts risk for future in …
Efficacy and tolerability of pharmacological treatments for insomnia in adults: A systematic review and network meta-analysis.
Yue JL, Chang XW, Zheng JW, Shi L, Xiang YJ, Que JY, Yuan K, Deng JH, Teng T, Li YY, Sun W, Sun HQ, Vitiello MV, Tang XD, Zhou XY, Bao YP, Shi J, Lu L. Yue JL, et al. Sleep Med Rev. 2023 Apr;68:101746. doi: 10.1016/j.smrv.2023.101746. Epub 2023 Jan 14. Sleep Med Rev. 2023. PMID: 36701954 Review.
Zaleplon and eszopiclone had better efficacy than placebo for TST and SQ respectively. MRAs may also be efficacious for sleep-onset insomnia with good safety. However, the long-term adverse effects of all medications are unclear. ...
Zaleplon and eszopiclone had better efficacy than placebo for TST and SQ respectively. MRAs may also be efficacious for sleep-onse …
Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.
Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Sateia MJ, et al. J Clin Sleep Med. 2017 Feb 15;13(2):307-349. doi: 10.5664/jcsm.6470. J Clin Sleep Med. 2017. PMID: 27998379 Free PMC article.
(WEAK). We suggest that clinicians use zaleplon as a treatment for sleep onset insomnia (versus no treatment) in adults. (WEAK). We suggest that clinicians use zolpidem as a treatment for sleep onset and sleep maintenance insomnia (versus no treatment) in adu …
(WEAK). We suggest that clinicians use zaleplon as a treatment for sleep onset insomnia (versus no treatment) in adults …
Circadian aspects in the aetiology and pathophysiology of insomnia.
Lack LC, Micic G, Lovato N. Lack LC, et al. J Sleep Res. 2023 Dec;32(6):e13976. doi: 10.1111/jsr.13976. Epub 2023 Aug 3. J Sleep Res. 2023. PMID: 37537965 Review.
Despite the separation of insomnia and circadian rhythm disorders in diagnostic nosology implying independent pathophysiology, there is considerable evidence of co-morbidity and interaction between them. Sleep onset insomnia is associated with later timed cir …
Despite the separation of insomnia and circadian rhythm disorders in diagnostic nosology implying independent pathophysiology, there is cons …
Sleep Disorders and Future Diagnosis of Parkinsonism: A Prospective Study Using the Canadian Longitudinal Study on Aging.
Zolfaghari S, Yao CW, Wolfson C, Pelletier A, Postuma RB. Zolfaghari S, et al. J Parkinsons Dis. 2022;12(1):257-266. doi: 10.3233/JPD-212796. J Parkinsons Dis. 2022. PMID: 34744049
RESULTS: We identified 58 incident-parkinsonism cases and 580 matched controls (65.5%male, mean age = 69.60, SD = 8.0). Baseline symptoms of sleep-onset insomnia (12.1%vs. 13.0%, Adjusted OR[95%CI] = 0.87[0.32,2.33]), sleep-maintenance insomnia (24.1%vs. 20.2 …
RESULTS: We identified 58 incident-parkinsonism cases and 580 matched controls (65.5%male, mean age = 69.60, SD = 8.0). Baseline symptoms of …
Prevalence of chronic insomnia in patients with obstructive sleep apnea.
Stelzer FG, Garcia E, Schorr F, Barea LM, Barros HT. Stelzer FG, et al. Braz J Psychiatry. 2021 Jul-Aug;43(4):370-375. doi: 10.1590/1516-4446-2019-0814. Braz J Psychiatry. 2021. PMID: 32997071 Free PMC article.
There was a trend towards older age in the CIOSA group. Sex was not associated with CIOSA. Sleep-maintenance and sleep-onset insomnia predominated in the sample. Beck's depression and anxiety inventory scores were higher in the CIOSA group. ...
There was a trend towards older age in the CIOSA group. Sex was not associated with CIOSA. Sleep-maintenance and sleep-onset …
Comparative efficacy of hypnotics in young and middle-aged adults with insomnia: a systematic review and network meta-analysis.
Hasan F, Lee HC, Chen PY, Wang YH, Yuliana LT, Romadlon DS, Tu YK, Chiu HY. Hasan F, et al. Sleep Breath. 2023 Oct;27(5):2021-2030. doi: 10.1007/s11325-023-02812-5. Epub 2023 Mar 16. Sleep Breath. 2023. PMID: 36928548
The results of sensitivity analysis remained unchanged after the exclusion of studies reporting long-term effects. CONCLUSION: Zolpidem is recommended for managing sleep-onset insomnia and sleep maintenance insomnia but should be used with caution because of …
The results of sensitivity analysis remained unchanged after the exclusion of studies reporting long-term effects. CONCLUSION: Zolpidem is r …
Difficulty in initiating sleep is associated with poor morning cardiovascular function.
Tsai HJ, Kuo TBJ, Yang AC, Tsai SJ, Yang CCH. Tsai HJ, et al. Psychiatry Res. 2021 Jan;295:113518. doi: 10.1016/j.psychres.2020.113518. Epub 2020 Oct 21. Psychiatry Res. 2021. PMID: 33189366
Insomnia is a risk factor for hypertension and cardiovascular events, and this association is strongest for sleep-onset insomnia. This study explored morning cardiovascular function in individuals with sleep-onset insomnia by analysing he …
Insomnia is a risk factor for hypertension and cardiovascular events, and this association is strongest for sleep-onset ins …
Co-occurring insomnia and obstructive sleep apnea.
Lichstein KL, Justin Thomas S, Woosley JA, Geyer JD. Lichstein KL, et al. Sleep Med. 2013 Sep;14(9):824-9. doi: 10.1016/j.sleep.2013.02.008. Epub 2013 Jun 13. Sleep Med. 2013. PMID: 23768836
76 results