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Quoted phrase not found in phrase index: "Soft tissue amyloid neoplasm"
Page 1
Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors.
Gounder M, Ratan R, Alcindor T, Schöffski P, van der Graaf WT, Wilky BA, Riedel RF, Lim A, Smith LM, Moody S, Attia S, Chawla S, D'Amato G, Federman N, Merriam P, Van Tine BA, Vincenzi B, Benson C, Bui NQ, Chugh R, Tinoco G, Charlson J, Dileo P, Hartner L, Lapeire L, Mazzeo F, Palmerini E, Reichardt P, Stacchiotti S, Bailey HH, Burgess MA, Cote GM, Davis LE, Deshpande H, Gelderblom H, Grignani G, Loggers E, Philip T, Pressey JG, Kummar S, Kasper B. Gounder M, et al. N Engl J Med. 2023 Mar 9;388(10):898-912. doi: 10.1056/NEJMoa2210140. N Engl J Med. 2023. PMID: 36884323 Clinical Trial.
BACKGROUND: Desmoid tumors are rare, locally aggressive, highly recurrent soft-tissue tumors without approved treatments. METHODS: We conducted a phase 3, international, double-blind, randomized, placebo-controlled trial of nirogacestat in adults with progressing de …
BACKGROUND: Desmoid tumors are rare, locally aggressive, highly recurrent soft-tissue tumors without approved treatments. METH …
Update on treatment of light chain amyloidosis.
Mahmood S, Palladini G, Sanchorawala V, Wechalekar A. Mahmood S, et al. Haematologica. 2014 Feb;99(2):209-21. doi: 10.3324/haematol.2013.087619. Haematologica. 2014. PMID: 24497558 Free PMC article. Review.
Light chain amyloidosis is the most common type of amyloidosis as a consequence of protein misfolding of aggregates composed of amyloid fibrils. The clinical features are dependent on the organs involved, typically cardiac, renal, hepatic, peripheral and autonomic neuropat …
Light chain amyloidosis is the most common type of amyloidosis as a consequence of protein misfolding of aggregates composed of amyloid
Supportive Care for Patients with Systemic Light Chain Amyloidosis.
Wong SW, Fogaren T. Wong SW, et al. Hematol Oncol Clin North Am. 2020 Dec;34(6):1177-1191. doi: 10.1016/j.hoc.2020.08.007. Hematol Oncol Clin North Am. 2020. PMID: 33099432 Review.
Light chain amyloidosis is a disease in which clonal plasma cells produce toxic immunoglobulin light chains that form amyloid fibrils with deposition in organs, most commonly the heart and kidneys, but also the nervous system, gastrointestinal tract, and soft tis
Light chain amyloidosis is a disease in which clonal plasma cells produce toxic immunoglobulin light chains that form amyloid fibrils …
Current management and recent progress in desmoid tumors.
Zhou MY, Bui NQ, Charville GW, Ghanouni P, Ganjoo KN. Zhou MY, et al. Cancer Treat Res Commun. 2022;31:100562. doi: 10.1016/j.ctarc.2022.100562. Epub 2022 Apr 16. Cancer Treat Res Commun. 2022. PMID: 35460976 Free article. Review.
Desmoid tumors are rare soft tissue tumors that can have aggressive infiltrative growth and relapse locally. ...
Desmoid tumors are rare soft tissue tumors that can have aggressive infiltrative growth and relapse locally. ...
Bone marrow amyloid: a comprehensive analysis of 1,469 samples, including amyloid type, clinical features, and morphologic distribution.
Chiu A, Dasari S, Kurtin PJ, Theis JD, Vrana JA, Dispenzieri A, Rech KL, Dao LN, Howard MT, Grogan M, McPhail ED. Chiu A, et al. Amyloid. 2022 Sep;29(3):156-164. doi: 10.1080/13506129.2022.2031963. Epub 2022 Feb 9. Amyloid. 2022. PMID: 35135386
Although there were characteristic morphologic features, including periosteal soft tissue and/or vascular involvement in ATTR, interstitial vascular involvement in AA, and variable anatomic compartment involvement in AL, none were pathognomonic. ...Amyloid ty …
Although there were characteristic morphologic features, including periosteal soft tissue and/or vascular involvement in ATTR, …
Soft tissue, joint, and bone manifestations of AL amyloidosis: clinical presentation, molecular features, and survival.
Prokaeva T, Spencer B, Kaut M, Ozonoff A, Doros G, Connors LH, Skinner M, Seldin DC. Prokaeva T, et al. Arthritis Rheum. 2007 Nov;56(11):3858-68. doi: 10.1002/art.22959. Arthritis Rheum. 2007. PMID: 17968927 Free article.
RESULTS: Soft tissue and bone involvement occurred in 42.9% of the patients, and 9.4% had dominant soft tissue and bone involvement. ...CONCLUSION: Amyloid infiltration into soft tissue, joints, periarticular structures, and bones …
RESULTS: Soft tissue and bone involvement occurred in 42.9% of the patients, and 9.4% had dominant soft tissue a …
Tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue: new entities and new variants of old entities recorded during the last 25 years. Part XII: appendix.
Bisceglia M, Spagnolo D, Galliani C, Fisher C, Suster S, Kazakov DV, Cooper K, Michal M. Bisceglia M, et al. Pathologica. 2006 Aug;98(4):239-98. Pathologica. 2006. PMID: 17175794 Review.
In an eleven part series published in Pathologica, we have presented various tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue (ST), which emerged as new entities or as variants of established entities during the last quarter …
In an eleven part series published in Pathologica, we have presented various tumoral, quasitumoral and pseudotumoral lesions of the superfic …
Oral soft tissue alterations in patients with neurofibromatosis.
Jouhilahti EM, Visnapuu V, Soukka T, Aho H, Peltonen S, Happonen RP, Peltonen J. Jouhilahti EM, et al. Clin Oral Investig. 2012 Apr;16(2):551-8. doi: 10.1007/s00784-011-0519-x. Epub 2011 Feb 8. Clin Oral Investig. 2012. PMID: 21301902
Our aim was to characterize the type and frequency of oral soft tissue alterations in neurofibromatosis. A total of 103 patients with neurofibromatosis 1 (NF1) and three patients with neurofibromatosis 2 (NF2) were clinically evaluated for their oral soft
Our aim was to characterize the type and frequency of oral soft tissue alterations in neurofibromatosis. A total of 103 patien …
Submucosal neoplasms of the laryngeal introitus.
Friedman AD, Burns JA, Lutch MJ, Zeitels SM. Friedman AD, et al. J Laryngol Otol. 2012 Jul;126(7):706-13. doi: 10.1017/S0022215112000928. Epub 2012 May 25. J Laryngol Otol. 2012. PMID: 22624973
BACKGROUND: The differential diagnosis of endolaryngeal mesenchymal neoplasms includes a wide spectrum of benign and malignant pathologies, which have been rarely photo-documented and assessed as a group. ...Submucosal squamous cell carcinomas, mucosal cysts, amyloid
BACKGROUND: The differential diagnosis of endolaryngeal mesenchymal neoplasms includes a wide spectrum of benign and malignant pathol …
Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery.
Wininger AE, Phelps BM, Le JT, Harris JD, Trachtenberg BH, Liberman SR. Wininger AE, et al. BMC Musculoskelet Disord. 2021 Jan 8;22(1):51. doi: 10.1186/s12891-020-03912-z. BMC Musculoskelet Disord. 2021. PMID: 33419417 Free PMC article.
BACKGROUND: Transthyretin and immunoglobulin light-chain amyloidoses cause amyloid deposition throughout various organ systems. Recent evidence suggests that soft tissue amyloid deposits may lead to orthopedic conditions before cardiac manifestations o …
BACKGROUND: Transthyretin and immunoglobulin light-chain amyloidoses cause amyloid deposition throughout various organ systems. Recen …
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