Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1997 1
1999 1
2001 1
2003 1
2006 2
2007 1
2009 2
2010 1
2011 2
2012 2
2015 1
2016 1
2017 2
2018 2
2019 1
2020 2
2021 2
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

25 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Spermatogenic failure 15"
Page 1
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene-disease relationships.
Houston BJ, Riera-Escamilla A, Wyrwoll MJ, Salas-Huetos A, Xavier MJ, Nagirnaja L, Friedrich C, Conrad DF, Aston KI, Krausz C, Tüttelmann F, O'Bryan MK, Veltman JA, Oud MS. Houston BJ, et al. Hum Reprod Update. 2021 Dec 21;28(1):15-29. doi: 10.1093/humupd/dmab030. Hum Reprod Update. 2021. PMID: 34498060 Free PMC article.
We assessed the experimental quality, patient phenotype assessment and functional evidence based on gene expression, mutant in-vitro cell and in-vivo animal model phenotypes. A final score was used to determine the clinical validity of each GDR, across the following five c …
We assessed the experimental quality, patient phenotype assessment and functional evidence based on gene expression, mutant in-vitro cell an …
Genetic causes of spermatogenic failure.
Massart A, Lissens W, Tournaye H, Stouffs K. Massart A, et al. Asian J Androl. 2012 Jan;14(1):40-8. doi: 10.1038/aja.2011.67. Epub 2011 Dec 5. Asian J Androl. 2012. PMID: 22138898 Free PMC article. Review.
Approximately 10%-15% of couples are infertile, and a male factor is involved in almost half of these cases. This observation is due in part to defects in spermatogenesis, and the underlying causes, including genetic abnormalities, remain largely unknown. ...
Approximately 10%-15% of couples are infertile, and a male factor is involved in almost half of these cases. This observation …
AZFc deletions and spermatogenic failure: a population-based survey of 20,000 Y chromosomes.
Rozen SG, Marszalek JD, Irenze K, Skaletsky H, Brown LG, Oates RD, Silber SJ, Ardlie K, Page DC. Rozen SG, et al. Am J Hum Genet. 2012 Nov 2;91(5):890-6. doi: 10.1016/j.ajhg.2012.09.003. Epub 2012 Oct 25. Am J Hum Genet. 2012. PMID: 23103232 Free PMC article.
Deletions involving the Y chromosome's AZFc region are the most common known genetic cause of severe spermatogenic failure (SSF). Six recurrent interstitial deletions affecting the region have been reported, but their population genetics are largely unexplored. ...T …
Deletions involving the Y chromosome's AZFc region are the most common known genetic cause of severe spermatogenic failure (SS …
High serum FSH is not a risk factor for low bone mineral density in infertile men.
Antonio L, Priskorn L, Olesen IA, Petersen JH, Vanderschueren D, Jørgensen N. Antonio L, et al. Bone. 2020 Jul;136:115366. doi: 10.1016/j.bone.2020.115366. Epub 2020 Apr 15. Bone. 2020. PMID: 32304878
METHODS: One hundred and thirty-seven men with a history of male factor infertility due to spermatogenic failure (SgF men) as well as a control group of 70 men from couples treated with IVF for female factor infertility (non-SgF men) were included in a long-term fol …
METHODS: One hundred and thirty-seven men with a history of male factor infertility due to spermatogenic failure (SgF men) as …
Factor V Leiden is associated with increased sperm count.
van Mens TE, Joensen UN, Bochdanovits Z, Takizawa A, Peter J, Jørgensen N, Szecsi PB, Meijers JCM, Weiler H, Rajpert-De Meyts E, Repping S, Middeldorp S. van Mens TE, et al. Hum Reprod. 2017 Nov 1;32(11):2332-2339. doi: 10.1093/humrep/dex287. Hum Reprod. 2017. PMID: 28927238
SUMMARY ANSWER: Carriers of FVL have a higher total sperm count than non-FVL-carriers, which could not be explained by genetic linkage or by observations in a FVL-mouse model. WHAT IS KNOWN ALREADY: FVL has a high prevalence in Caucasians despite detrimental health effects …
SUMMARY ANSWER: Carriers of FVL have a higher total sperm count than non-FVL-carriers, which could not be explained by genetic linkage or by …
Meiotic arrest occurs most frequently at metaphase and is often incomplete in azoospermic men.
Enguita-Marruedo A, Sleddens-Linkels E, Ooms M, de Geus V, Wilke M, Blom E, Dohle GR, Looijenga LHJ, van Cappellen W, Baart EB, Baarends WM. Enguita-Marruedo A, et al. Fertil Steril. 2019 Dec;112(6):1059-1070.e3. doi: 10.1016/j.fertnstert.2019.08.004. Epub 2019 Nov 22. Fertil Steril. 2019. PMID: 31767154 Free article.
PATIENT(S): Forty-eight patients with confirmed spermatogenic impairment (Johnsen scores 3-6) and 15 controls (Johnsen score 10). ...Incomplete metaphase arrest was observed in 17% of the patients. Only four patients (8%) displayed a failure …
PATIENT(S): Forty-eight patients with confirmed spermatogenic impairment (Johnsen scores 3-6) and 15 controls (Johnsen …
Variants in GCNA, X-linked germ-cell genome integrity gene, identified in men with primary spermatogenic failure.
Hardy JJ, Wyrwoll MJ, Mcfadden W, Malcher A, Rotte N, Pollock NC, Munyoki S, Veroli MV, Houston BJ, Xavier MJ, Kasak L, Punab M, Laan M, Kliesch S, Schlegel P, Jaffe T, Hwang K, Vukina J, Brieño-Enríquez MA, Orwig K, Yanowitz J, Buszczak M, Veltman JA, Oud M, Nagirnaja L, Olszewska M, O'Bryan MK, Conrad DF, Kurpisz M, Tüttelmann F, Yatsenko AN; GEMINI Consortium. Hardy JJ, et al. Hum Genet. 2021 Aug;140(8):1169-1182. doi: 10.1007/s00439-021-02287-y. Epub 2021 May 7. Hum Genet. 2021. PMID: 33963445 Free PMC article.
A critical element of successful spermatogenesis is maintenance of genome integrity. Here, we present a genomic study of spermatogenic failure (SPGF). Our initial analysis (n = 176) did not reveal known gene-candidates but identified a potentially significant single …
A critical element of successful spermatogenesis is maintenance of genome integrity. Here, we present a genomic study of spermatogenic …
Screening for AZFc partial deletions in Dravidian men with nonobstructive azoospermia and oligozoospermia.
Vijesh VV, Nambiar V, Mohammed SI, Sukumaran S, Suganthi R. Vijesh VV, et al. Genet Test Mol Biomarkers. 2015 Mar;19(3):150-5. doi: 10.1089/gtmb.2014.0251. Epub 2015 Jan 16. Genet Test Mol Biomarkers. 2015. PMID: 25594150 Free PMC article.
Considering various genetic discoveries taking place today, it is evident that deletions in the AZFc region are the most common cause of severe spermatogenic failure (SSF) in various populations studied. However, it is significant to note that there is a paucity of …
Considering various genetic discoveries taking place today, it is evident that deletions in the AZFc region are the most common cause of sev …
Spermatogenic phenotype of testis-specific protein, Y-encoded, 1 (TSPY1) dosage deficiency is independent of variations in TSPY-like 1 (TSPYL1) and TSPY-like 5 (TSPYL5): a case-control study in a Han Chinese population.
Yang X, Leng X, Tu W, Liu Y, Xu J, Pei X, Ma Y, Yang D, Yang Y. Yang X, et al. Reprod Fertil Dev. 2018 Mar;30(3):555-562. doi: 10.1071/RD17146. Reprod Fertil Dev. 2018. PMID: 28847364
Testis-specific protein, Y-encoded, 1 (TSPY1) is involved in the regulation of spermatogenic efficiency via highly variable copy dosage, with dosage deficiency of the multicopy gene conferring an increased risk of spermatogenic failure. ...To explore the pote …
Testis-specific protein, Y-encoded, 1 (TSPY1) is involved in the regulation of spermatogenic efficiency via highly variable copy dosa …
Decrease in semen quality and Leydig cell function in infertile men: a longitudinal study.
Olesen IA, Joensen UN, Petersen JH, Almstrup K, Rajpert-De Meyts E, Carlsen E, McLachlan R, Juul A, Jørgensen N. Olesen IA, et al. Hum Reprod. 2018 Nov 1;33(11):1963-1974. doi: 10.1093/humrep/dey283. Hum Reprod. 2018. PMID: 30247578
WHAT IS KNOWN ALREADY: Male factors account for up to 50% of human infertility. The most common finding is spermatogenic failure (SgF) yet the life course of semen quality and testosterone production in such men has not been described. STUDY DESIGN, SIZE, DURATION: …
WHAT IS KNOWN ALREADY: Male factors account for up to 50% of human infertility. The most common finding is spermatogenic failure …
25 results