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Quoted phrase not found in phrase index: "Spermatogenic failure 2"
Page 1
Spermatogenic failure and the Y chromosome.
Krausz C, Casamonti E. Krausz C, et al. Hum Genet. 2017 May;136(5):637-655. doi: 10.1007/s00439-017-1793-8. Epub 2017 Apr 29. Hum Genet. 2017. PMID: 28456834 Review.
Its highly repetitive structure predisposes this chromosome to deletion/duplication events and is responsible for Y-linked copy-number variations (CNVs) with clinical relevance. The AZF deletions remove genes with predicted spermatogenic function en block and are th …
Its highly repetitive structure predisposes this chromosome to deletion/duplication events and is responsible for Y-linked copy-number varia …
Consequences of Y chromosome microdeletions beyond male infertility.
Colaco S, Modi D. Colaco S, et al. J Assist Reprod Genet. 2019 Jul;36(7):1329-1337. doi: 10.1007/s10815-019-01492-z. Epub 2019 Jun 18. J Assist Reprod Genet. 2019. PMID: 31214882 Free PMC article. Review.
The azoospermia factor (AZF) loci on the Y chromosome contain genes that were thought to be testis specific with their deletions leading to spermatogenic failure. However, beyond the testis, the AZF genes (mainly those in AZFa and AZFb loci) are widely expressed in …
The azoospermia factor (AZF) loci on the Y chromosome contain genes that were thought to be testis specific with their deletions leading to …
A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents.
Sapkota Y, Wilson CL, Zaidi AK, Moon W, Fon Tacer K, Lu L, Liu Q, Baedke J, Dhaduk R, Wang Z, Chemaitilly W, Krasin MJ, Berry FB, Zhang J, Hudson MM, Robison LL, Green DM, Yasui Y. Sapkota Y, et al. Cancer Res. 2020 Sep 1;80(17):3755-3764. doi: 10.1158/0008-5472.CAN-20-0093. Epub 2020 Jun 17. Cancer Res. 2020. PMID: 32554749 Free PMC article.

This association was replicated in two independent samples of SJLIFE survivors of European ancestry, including 34 nonirradiated male survivors treated with 0 < CED < 4,000 mg/m(2) (P = 3.1 10(-4)) and 24 male survivors treated with CED 4,000 mg/m(2) and radiot

…
This association was replicated in two independent samples of SJLIFE survivors of European ancestry, including 34 nonirradiated male survivo …
Microdeletions and microduplications linked to severe congenital disorders in infertile men.
Kikas T, Punab AM, Kasak L, Poolamets O, Vihljajev V, Pomm K, Reiman M, Tjagur S, Korrovits P, Punab M, Laan M. Kikas T, et al. Sci Rep. 2023 Jan 11;13(1):574. doi: 10.1038/s41598-023-27750-w. Sci Rep. 2023. PMID: 36631630 Free PMC article.
Data on the clinical validity of DNA copy number variants (CNVs) in spermatogenic failure (SPGF) is limited. This study analyzed the genome-wide CNV profile in 215 men with idiopathic SPGF and 62 normozoospermic fertile men, recruited at the Andrology Clinic, Tartu …
Data on the clinical validity of DNA copy number variants (CNVs) in spermatogenic failure (SPGF) is limited. This study analyz …
Hydrogen Sulfide As a Potential Target in Preventing Spermatogenic Failure and Testicular Dysfunction.
Wang J, Wang W, Li S, Han Y, Zhang P, Meng G, Xiao Y, Xie L, Wang X, Sha J, Chen Q, Moore PK, Wang R, Xiang W, Ji Y. Wang J, et al. Antioxid Redox Signal. 2018 Jun 1;28(16):1447-1462. doi: 10.1089/ars.2016.6968. Epub 2017 Oct 16. Antioxid Redox Signal. 2018. PMID: 28537489
Supplying exogenous H(2)S or overexpressing CBS could relieve the spermatogenic failure. ...CONCLUSION: H(2)S plays an important role in spermatogenic failure and testicular dysfunction mainly by its anti-inflammatory and antioxidative ef …
Supplying exogenous H(2)S or overexpressing CBS could relieve the spermatogenic failure. ...CONCLUSION: H(2)S pl …
AZFc deletions and spermatogenic failure: a population-based survey of 20,000 Y chromosomes.
Rozen SG, Marszalek JD, Irenze K, Skaletsky H, Brown LG, Oates RD, Silber SJ, Ardlie K, Page DC. Rozen SG, et al. Am J Hum Genet. 2012 Nov 2;91(5):890-6. doi: 10.1016/j.ajhg.2012.09.003. Epub 2012 Oct 25. Am J Hum Genet. 2012. PMID: 23103232 Free PMC article.
Deletions involving the Y chromosome's AZFc region are the most common known genetic cause of severe spermatogenic failure (SSF). Six recurrent interstitial deletions affecting the region have been reported, but their population genetics are largely unexplored. ...T …
Deletions involving the Y chromosome's AZFc region are the most common known genetic cause of severe spermatogenic failure (SS …
CHD7 missense variants and clinical characteristics of Chinese males with infertility.
Li L, Wang R, Yu Y, Zhang H, Jiang Y, Yang X, Liu R. Li L, et al. Mol Genet Genomic Med. 2020 Sep;8(9):e1372. doi: 10.1002/mgg3.1372. Epub 2020 Jun 22. Mol Genet Genomic Med. 2020. PMID: 32573075 Free PMC article.
The patients underwent clinical examination and reproductive hormone testing. A panel of genes including CHD7 and others related to spermatogenic failure was sequenced by targeted-gene exome sequencing. ...Although predicted to be benign, the variants of c.28 …
The patients underwent clinical examination and reproductive hormone testing. A panel of genes including CHD7 and others related to sperm …
The piRNA-pathway factor FKBP6 is essential for spermatogenesis but dispensable for control of meiotic LINE-1 expression in humans.
Wyrwoll MJ, Gaasbeek CM, Golubickaite I, Stakaitis R, Oud MS, Nagirnaja L, Dion C, Sindi EB, Leitch HG, Jayasena CN, Sironen A, Dicke AK, Rotte N, Stallmeyer B, Kliesch S, Grangeiro CHP, Araujo TF, Lasko P; Genetics of Male Infertility Initiative (GEMINI) consortium; D'Hauwers K, Smits RM, Ramos L, Xavier MJ, Conrad DF, Almstrup K, Veltman JA, Tüttelmann F, van der Heijden GW. Wyrwoll MJ, et al. Am J Hum Genet. 2022 Oct 6;109(10):1850-1866. doi: 10.1016/j.ajhg.2022.09.002. Epub 2022 Sep 22. Am J Hum Genet. 2022. PMID: 36150389 Free PMC article.
Infertility affects around 7% of the male population and can be due to severe spermatogenic failure (SPGF), resulting in no or very few sperm in the ejaculate. ...This will improve patient care by providing a causal diagnosis and will help to predict chances …
Infertility affects around 7% of the male population and can be due to severe spermatogenic failure (SPGF), resulting in no or …
Stem Cell Factor Receptor Immunoexpression in Adolescent Varicocele.
Arena S, Impellizzeri P, Fazzari C, Peri Flora M, Enrica A, Calabrese U, Centorrino A, Alibrandi A, Romeo C. Arena S, et al. Urol J. 2020 Jun 23;17(4):391-396. doi: 10.22037/uj.v0i0.5351. Urol J. 2020. PMID: 32207142 Free article.
The relationship between percentage of testicular asymmetry, number of tubular c-kit positive germ cells and severity of spermatogenic failure was assessed. RESULTS: The mean (SD; median) histological grade for spermatogenic failure in controls was 1.3 …
The relationship between percentage of testicular asymmetry, number of tubular c-kit positive germ cells and severity of spermatogenic …
Fertility problems in men carrying a translocation involved in breakpoints on chromosome 17p13: A retrospective, observational study.
Li R. Li R. Medicine (Baltimore). 2022 Dec 9;101(49):e32216. doi: 10.1097/MD.0000000000032216. Medicine (Baltimore). 2022. PMID: 36626513 Free PMC article.
Several breakpoints of chromosome 17 are related to important genes, which can lead to spermatogenic failure. This study aimed to identify the clinical features of 3 men with translocation karyotypes involving breakpoints on chromosome 17p13. ...The results suggest …
Several breakpoints of chromosome 17 are related to important genes, which can lead to spermatogenic failure. This study aimed …
72 results