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Quoted phrase not found in phrase index: "Spermatogenic failure 22"
Page 1
Microdeletions and microduplications linked to severe congenital disorders in infertile men.
Kikas T, Punab AM, Kasak L, Poolamets O, Vihljajev V, Pomm K, Reiman M, Tjagur S, Korrovits P, Punab M, Laan M. Kikas T, et al. Sci Rep. 2023 Jan 11;13(1):574. doi: 10.1038/s41598-023-27750-w. Sci Rep. 2023. PMID: 36631630 Free PMC article.
Data on the clinical validity of DNA copy number variants (CNVs) in spermatogenic failure (SPGF) is limited. This study analyzed the genome-wide CNV profile in 215 men with idiopathic SPGF and 62 normozoospermic fertile men, recruited at the Andrology Clinic, Tartu …
Data on the clinical validity of DNA copy number variants (CNVs) in spermatogenic failure (SPGF) is limited. This study analyz …
Testicular Growth and Pubertal Onset in GH-Deficient Children Treated With Growth Hormone: A Retrospective Study.
Cannarella R, Caruso M, Crafa A, Timpanaro TA, Lo Bianco M, Presti S, Condorelli RA, La Vignera S, Calogero AE. Cannarella R, et al. Front Endocrinol (Lausanne). 2021 Apr 2;12:619895. doi: 10.3389/fendo.2021.619895. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 33868165 Free PMC article.
The search for determinants of testicular growth in childhood is important for the primary prevention of spermatogenic failure. Therefore, this retrospective study aimed to evaluate the testicular growth and pubertal onset in deficient children treated recombinant h …
The search for determinants of testicular growth in childhood is important for the primary prevention of spermatogenic failure …
Testicular steroid sulfatase overexpression is associated with Leydig cell dysfunction in primary spermatogenic failure.
Lardone MC, Reyes IN, Ortiz E, Piottante A, Palma C, Ebensperger M, Castro A. Lardone MC, et al. Andrology. 2021 Mar;9(2):657-664. doi: 10.1111/andr.12950. Epub 2020 Dec 30. Andrology. 2021. PMID: 33290605 Free article.
BACKGROUND: Decreased testosterone (T) to LH ratio and increased 17beta-estradiol (E2) serum concentrations represent a common finding among patients with severe spermatogenic failure, suggesting a concurrent Leydig cell steroidogenic dysfunction. ...CONCLUSIONS: Ou …
BACKGROUND: Decreased testosterone (T) to LH ratio and increased 17beta-estradiol (E2) serum concentrations represent a common finding among …
High serum FSH is not a risk factor for low bone mineral density in infertile men.
Antonio L, Priskorn L, Olesen IA, Petersen JH, Vanderschueren D, Jørgensen N. Antonio L, et al. Bone. 2020 Jul;136:115366. doi: 10.1016/j.bone.2020.115366. Epub 2020 Apr 15. Bone. 2020. PMID: 32304878
METHODS: One hundred and thirty-seven men with a history of male factor infertility due to spermatogenic failure (SgF men) as well as a control group of 70 men from couples treated with IVF for female factor infertility (non-SgF men) were included in a long-term fol …
METHODS: One hundred and thirty-seven men with a history of male factor infertility due to spermatogenic failure (SgF men) as …
No association found between gr/gr deletions and infertility in Brazilian males.
Carvalho CM, Zuccherato LW, Bastos-Rodrigues L, Santos FR, Pena SD. Carvalho CM, et al. Mol Hum Reprod. 2006 Apr;12(4):269-73. doi: 10.1093/molehr/gal029. Epub 2006 Apr 5. Mol Hum Reprod. 2006. PMID: 16597640
A partial AZFc deletion named gr/gr has been singled out as a risk factor for spermatogenic failure. However, other authors have diagnosed it as a polymorphic deletion with no clinical relevance. ...We analysed 350 individuals (110 azoospermic, 122 fertile and 118 p …
A partial AZFc deletion named gr/gr has been singled out as a risk factor for spermatogenic failure. However, other authors ha …
A significant effect of the TSPY1 copy number on spermatogenesis efficiency and the phenotypic expression of the gr/gr deletion.
Shen Y, Yan Y, Liu Y, Zhang S, Yang D, Zhang P, Li L, Wang Y, Ma Y, Tao D, Yang Y. Shen Y, et al. Hum Mol Genet. 2013 Apr 15;22(8):1679-95. doi: 10.1093/hmg/ddt004. Epub 2013 Jan 10. Hum Mol Genet. 2013. PMID: 23307928
Our data revealed that the TSPY1 copy number distributions were significantly different among non-AZFc-deleted males with different spermatogenic phenotypes. Lower sperm production and an elevated risk of spermatogenic failure were observed in males wi …
Our data revealed that the TSPY1 copy number distributions were significantly different among non-AZFc-deleted males with different sperm …
Sperm DNA fragmentation levels in testicular sperm samples from azoospermic males as assessed by the sperm chromatin dispersion (SCD) test.
Meseguer M, Santiso R, Garrido N, Gil-Salom M, Remohí J, Fernandez JL. Meseguer M, et al. Fertil Steril. 2009 Nov;92(5):1638-45. doi: 10.1016/j.fertnstert.2008.08.106. Epub 2008 Nov 11. Fertil Steril. 2009. PMID: 19006791 Free article.
OBJECTIVE: To analyze sperm DNA fragmentation (SDF) in testicular sperm samples from patients with azoospermia either from spermatogenic failure or from duct obstruction. Several technologies can be applied in the evaluation of SDF, but given the ease and low costs, …
OBJECTIVE: To analyze sperm DNA fragmentation (SDF) in testicular sperm samples from patients with azoospermia either from spermatogenic …
Follow-up of men in the recovery period immediately after the cessation of gossypol treatment.
Meng GD, Zhu JC, Chen ZW, Wong LT, Zhang GY, Hu YZ, Ding JH, Wang XH, Qian SZ, Wang C, et al. Meng GD, et al. Contraception. 1988 Feb;37(2):119-28. doi: 10.1016/0010-7824(88)90122-9. Contraception. 1988. PMID: 3131064
However, 18 men (39%) had not recovered after a median follow-up of 1.9 years and, of these, 10 (22%) remained azoospermic. The failure of recovery was strongly associated with longer treatment, greater total dose of gossypol, smaller testicular volume, elevated FSH …
However, 18 men (39%) had not recovered after a median follow-up of 1.9 years and, of these, 10 (22%) remained azoospermic. The fa …
Pseudoautosomal abnormalities in terminal AZFb+c deletions are associated with isochromosomes Yp and may lead to abnormal growth and neuropsychiatric function.
Castro A, Rodríguez F, Flórez M, López P, Curotto B, Martínez D, Maturana A, Lardone MC, Palma C, Mericq V, Ebensperger M, Cassorla F. Castro A, et al. Hum Reprod. 2017 Feb;32(2):465-475. doi: 10.1093/humrep/dew333. Epub 2017 Jan 5. Hum Reprod. 2017. PMID: 28057878
WHAT IS KNOWN ALREADY: The microdeletions in the long arm of the Y chromosome (Yq) that include the loss of one to three AZF regions, referred to as Yq microdeletions, constitute the most important known etiological factor for primary spermatogenic failure. Recently …
WHAT IS KNOWN ALREADY: The microdeletions in the long arm of the Y chromosome (Yq) that include the loss of one to three AZF regions, referr …
Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility.
Galan JJ, Guarducci E, Nuti F, Gonzalez A, Ruiz M, Ruiz A, Krausz C. Galan JJ, et al. Hum Reprod. 2007 Feb;22(2):444-9. doi: 10.1093/humrep/del391. Epub 2006 Nov 10. Hum Reprod. 2007. PMID: 17099213
MATERIALS AND METHODS: A large group of patients (total number=335) and controls (total number=567) of two Caucasian populations were analysed for the AGATA haplotype and SNP12 to verify whether this genetic variant and its tag SNP were associated with cryptorchidism or with seve …
MATERIALS AND METHODS: A large group of patients (total number=335) and controls (total number=567) of two Caucasian populations were analys …
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