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Quoted phrase not found in phrase index: "Spermatogenic failure 34"
Page 1
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M. Radaelli E, et al. Elife. 2023 Jul 28;12:e84710. doi: 10.7554/eLife.84710. Elife. 2023. PMID: 37505079 Free PMC article.
Interestingly, genetic modifications of PINK1, PGAM5, and TTC19 - three major substrates of PARL with important roles in mitochondrial homeostasis - fail to reproduce or modify this severe phenotype, indicating that the spermatogenic arrest arises from distinct molecular p …
Interestingly, genetic modifications of PINK1, PGAM5, and TTC19 - three major substrates of PARL with important roles in mitochondrial homeo …
A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents.
Sapkota Y, Wilson CL, Zaidi AK, Moon W, Fon Tacer K, Lu L, Liu Q, Baedke J, Dhaduk R, Wang Z, Chemaitilly W, Krasin MJ, Berry FB, Zhang J, Hudson MM, Robison LL, Green DM, Yasui Y. Sapkota Y, et al. Cancer Res. 2020 Sep 1;80(17):3755-3764. doi: 10.1158/0008-5472.CAN-20-0093. Epub 2020 Jun 17. Cancer Res. 2020. PMID: 32554749 Free PMC article.

This association was replicated in two independent samples of SJLIFE survivors of European ancestry, including 34 nonirradiated male survivors treated with 0 < CED < 4,000 mg/m(2) (P = 3.1 10(-4)) and 24 male survivors treated with CED 4,000 mg/m(2) and radiotherapy

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This association was replicated in two independent samples of SJLIFE survivors of European ancestry, including 34 nonirradiated male …
Histological and hormonal testicular function in oligo/azoospermic infertile men.
Lardone MC, Piottante A, Valdevenito R, Ebensperger M, Castro A. Lardone MC, et al. Andrologia. 2013 Dec;45(6):379-85. doi: 10.1111/and.12026. Epub 2012 Sep 26. Andrologia. 2013. PMID: 23013062
One hundred and 93 azo/oligozoospermic patients were diagnosed as: complete sertoli cell only syndrome (cSCOS), n = 76; focal SCOS, n = 31; maturation arrest, n = 34; hypospermatogenesis, n = 17; mixed atrophy, n = 25; and severe atrophy, n = 10. ...Considering all subject …
One hundred and 93 azo/oligozoospermic patients were diagnosed as: complete sertoli cell only syndrome (cSCOS), n = 76; focal SCOS, n = 31; …
AZF microdeletions and partial deletions of AZFc region on the Y chromosome in Moroccan men.
Imken L, El Houate B, Chafik A, Nahili H, Boulouiz R, Abidi O, Chadli E, Louanjli N, Elfath A, Hassar M, McElreavey K, Barakat A, Rouba H. Imken L, et al. Asian J Androl. 2007 Sep;9(5):674-8. doi: 10.1111/j.1745-7262.2007.00290.x. Asian J Androl. 2007. PMID: 17712485 Free article.
The overall AZFc deletion frequency was low (4/127, 3.15%). AZF microdeletions were not observed in either oligoasthenoteratozoospermia (OATS) or the control. ...In addition, two b2/b3 deletions were identified in two azoospermic subjects (2/149, 1.34%) but not in t …
The overall AZFc deletion frequency was low (4/127, 3.15%). AZF microdeletions were not observed in either oligoasthenoteratozoosperm …
Y chromosome TSPY copy numbers and semen quality.
Nickkholgh B, Noordam MJ, Hovingh SE, van Pelt AM, van der Veen F, Repping S. Nickkholgh B, et al. Fertil Steril. 2010 Oct;94(5):1744-7. doi: 10.1016/j.fertnstert.2009.09.051. Epub 2009 Nov 14. Fertil Steril. 2010. PMID: 19917507 Free article.
Cases had a median TSPY copy number of 35 (range 20-73), whereas controls had a median TSPY copy number of 34 (range 26-76). This difference was not statistically significant. CONCLUSION(S): We found no association between TSPY copy numbers and severe spermatogenic …
Cases had a median TSPY copy number of 35 (range 20-73), whereas controls had a median TSPY copy number of 34 (range 26-76). This dif …
No association found between gr/gr deletions and infertility in Brazilian males.
Carvalho CM, Zuccherato LW, Bastos-Rodrigues L, Santos FR, Pena SD. Carvalho CM, et al. Mol Hum Reprod. 2006 Apr;12(4):269-73. doi: 10.1093/molehr/gal029. Epub 2006 Apr 5. Mol Hum Reprod. 2006. PMID: 16597640
A partial AZFc deletion named gr/gr has been singled out as a risk factor for spermatogenic failure. However, other authors have diagnosed it as a polymorphic deletion with no clinical relevance. ...We analysed 350 individuals (110 azoospermic, 122 fertile and 118 p …
A partial AZFc deletion named gr/gr has been singled out as a risk factor for spermatogenic failure. However, other authors ha …
Assessing the cognitive and behavioral development of 3-year-old children born from fathers with severe male infertility.
Cheung S, Neri QV, Squires J, Rosenwaks Z, Palermo GD. Cheung S, et al. Am J Obstet Gynecol. 2021 May;224(5):508.e1-508.e11. doi: 10.1016/j.ajog.2020.11.030. Epub 2020 Nov 26. Am J Obstet Gynecol. 2021. PMID: 33248137 Free article.
Ages and Stages Questionnaires outcomes were also compared for the offspring conceived via in vitro fertilization and intracytoplasmic sperm injection by gender; however, no significant differences were observed. In addition, 5 separate subanalyses were then conducted excl …
Ages and Stages Questionnaires outcomes were also compared for the offspring conceived via in vitro fertilization and intracytoplasmic sperm …
Transcriptional levels of four Y chromosome-linked AZF genes in azoospermic men and their association with successful sperm retrieval.
Kuo PL, Lin YH, Teng YN, Hsu CC, Lin JS, Lin YM. Kuo PL, et al. Urology. 2004 Jan;63(1):131-6; discussion 136. doi: 10.1016/j.urology.2003.08.048. Urology. 2004. PMID: 14751364
In contrast, statistically significant decreases were found in the transcript ratios of RBMY1 and DAZ in patients with spermatogenic failure (P = 0.0002 and P = 0.002, respectively). The transcript ratios of USP9Y and DBY were not associated with the results of sper …
In contrast, statistically significant decreases were found in the transcript ratios of RBMY1 and DAZ in patients with spermatogenic …
Sequencing of a 'mouse azoospermia' gene panel in azoospermic men: identification of RNF212 and STAG3 mutations as novel genetic causes of meiotic arrest.
Riera-Escamilla A, Enguita-Marruedo A, Moreno-Mendoza D, Chianese C, Sleddens-Linkels E, Contini E, Benelli M, Natali A, Colpi GM, Ruiz-Castañé E, Maggi M, Baarends WM, Krausz C. Riera-Escamilla A, et al. Hum Reprod. 2019 Jun 4;34(6):978-988. doi: 10.1093/humrep/dez042. Hum Reprod. 2019. PMID: 31125047
The testis histology of the 31 unrelated NOA patients was as follows: 20 Sertoli cell-only syndrome (SCOS), 11 spermatogenic arrest (6 spermatogonial arrest and 5 spermatocytic arrest). ...WIDER IMPLICATIONS OF THE FINDINGS: Our study represents an additional step towards …
The testis histology of the 31 unrelated NOA patients was as follows: 20 Sertoli cell-only syndrome (SCOS), 11 spermatogenic arrest ( …
Does the gonadotrophic axis play a role in the pathogenesis of Sertoli-cell-only syndrome?
Leifke E, Simoni M, Kamischke A, Gromoll J, Bergmann M, Nieschlag E. Leifke E, et al. Int J Androl. 1997 Feb;20(1):29-36. doi: 10.1046/j.1365-2605.1997.00102.x. Int J Androl. 1997. PMID: 9202988

Men with SCO showed significantly higher FSH in-vitro bioactivity (34.9 +/- 5.0 IU/l) than controls (9.6 +/- 0.8 IU/l: p < 0.01), as well as significantly elevated FSH immunoactivity (14.9 +/- 1.7 IU/l) compared to controls (3.1 +/- 0.5; p < 0.01). ...In the serum of

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Men with SCO showed significantly higher FSH in-vitro bioactivity (34.9 +/- 5.0 IU/l) than controls (9.6 +/- 0.8 IU/l: p < 0.01),

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11 results