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Quoted phrase not found in phrase index: "Spermatogenic failure 7"
Page 1
External and Genetic Conditions Determining Male Infertility.
Kamiński P, Baszyński J, Jerzak I, Kavanagh BP, Nowacka-Chiari E, Polanin M, Szymański M, Woźniak A, Kozera W. Kamiński P, et al. Int J Mol Sci. 2020 Jul 24;21(15):5274. doi: 10.3390/ijms21155274. Int J Mol Sci. 2020. PMID: 32722328 Free PMC article. Review.
Among mutations in chromosome 7, impairments in the cystic fibrosis transmembrane conductance regulator CFTR gene are destructive for fertility in cystic fibrosis, when spermatic ducts undergo complete obstruction. ...Alongside karyotype abnormalities AZF microdeletions ar …
Among mutations in chromosome 7, impairments in the cystic fibrosis transmembrane conductance regulator CFTR gene are destructive for …
Hydrogen Sulfide As a Potential Target in Preventing Spermatogenic Failure and Testicular Dysfunction.
Wang J, Wang W, Li S, Han Y, Zhang P, Meng G, Xiao Y, Xie L, Wang X, Sha J, Chen Q, Moore PK, Wang R, Xiang W, Ji Y. Wang J, et al. Antioxid Redox Signal. 2018 Jun 1;28(16):1447-1462. doi: 10.1089/ars.2016.6968. Epub 2017 Oct 16. Antioxid Redox Signal. 2018. PMID: 28537489
Supplying exogenous H(2)S or overexpressing CBS could relieve the spermatogenic failure. This occurred primarily through the combination of anti-inflammatory and antioxidative effects. INNOVATION: These results provide the first indication that H(2)S is important fo …
Supplying exogenous H(2)S or overexpressing CBS could relieve the spermatogenic failure. This occurred primarily through the c …
Systematic molecular analyses for 115 karyotypically normal men with isolated non-obstructive azoospermia.
Muranishi Y, Kobori Y, Katoh-Fukui Y, Tamaoka S, Hattori A, Osaka A, Okada H, Nakabayashi K, Hata K, Kawai T, Ogata-Kawata H, Iwahata T, Saito K, Kon M, Shinohara N, Fukami M. Muranishi Y, et al. Hum Reprod. 2024 May 2;39(5):1131-1140. doi: 10.1093/humrep/deae057. Hum Reprod. 2024. PMID: 38511217
When the gr/gr deletion, a common polymorphism in Japan, was excluded from data analyses, the total frequency of CNVs was 23/75 (30.7%). This frequency is higher than that of the reference data in Japan and China (11.1% and 14.7%, respectively). ...These results bro …
When the gr/gr deletion, a common polymorphism in Japan, was excluded from data analyses, the total frequency of CNVs was 23/75 (30.7 …
A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents.
Sapkota Y, Wilson CL, Zaidi AK, Moon W, Fon Tacer K, Lu L, Liu Q, Baedke J, Dhaduk R, Wang Z, Chemaitilly W, Krasin MJ, Berry FB, Zhang J, Hudson MM, Robison LL, Green DM, Yasui Y. Sapkota Y, et al. Cancer Res. 2020 Sep 1;80(17):3755-3764. doi: 10.1158/0008-5472.CAN-20-0093. Epub 2020 Jun 17. Cancer Res. 2020. PMID: 32554749 Free PMC article.
No association was observed among survivors not exposed to alkylating agents included in the CED (P > 0.29). rs7784118 conferred 3.48- and 9.73-fold increases in risk for clinically defined oligospermia and azoospermia and improved prediction of normospermic, oligospermic, and …
No association was observed among survivors not exposed to alkylating agents included in the CED (P > 0.29). rs7784118 conferred 3.48- an …
Association of DAZL haplotypes with spermatogenic failure in infertile men.
Teng YN, Lin YM, Sun HF, Hsu PY, Chung CL, Kuo PL. Teng YN, et al. Fertil Steril. 2006 Jul;86(1):129-35. doi: 10.1016/j.fertnstert.2005.12.027. Epub 2006 May 30. Fertil Steril. 2006. PMID: 16730721 Clinical Trial.
Haplotypes AACTA, AAACG, and GGACG were overtransmitted in patients with spermatogenic failure, whereas haplotypes AACCG and AAATA were undertransmitted in these patients. CONCLUSION(S): Our study suggests the association of autosomal DAZL haplotypes with human s …
Haplotypes AACTA, AAACG, and GGACG were overtransmitted in patients with spermatogenic failure, whereas haplotypes AACCG and A …
Exome-based search for recurrent disease-causing alleles in Russian population.
Yanus GA, Akhapkina TA, Whitehead AJ, Bizin IV, Iyevleva AG, Kuligina ES, Aleksakhina SN, Anisimova MO, Holmatov MM, Romanko AA, Zaitseva OA, Yatsuk OS, Zagorodnev KA, Matsneva MA, Koloskov AV, Togo AV, Suspitsin EN, Imyanitov EN. Yanus GA, et al. Eur J Med Genet. 2019 Jul;62(7):103656. doi: 10.1016/j.ejmg.2019.04.013. Epub 2019 Apr 24. Eur J Med Genet. 2019. PMID: 31028847
Exomes of 27 Russian subjects were analyzed for the presence of medically relevant alleles, such as protein-truncating variants (PTVs) in known recessive disease-associated genes and pathogenic missense mutations included in the ClinVar database. 36 variants (24 PTVs and 12 amino …
Exomes of 27 Russian subjects were analyzed for the presence of medically relevant alleles, such as protein-truncating variants (PTVs) in kn …
Risk Y-haplotypes and pathogenic variants of Arab-ancestry boys with autism by an exome-wide association study.
Alsubaie LM, Alsuwat HS, Almandil NB, AlSulaiman A, AbdulAzeez S, Borgio JF. Alsubaie LM, et al. Mol Biol Rep. 2020 Oct;47(10):7623-7632. doi: 10.1007/s11033-020-05832-6. Epub 2020 Sep 29. Mol Biol Rep. 2020. PMID: 32996047 Clinical Trial.
The significant predisposed genes with functional variants of Y-chromomere are strongly connected with spermatogenic failure (p = 8.02 10(-8)), azoospermia (p = 6.32 10(-7)), partial chromosome Y deletion (p = 7.66 10(-6)), HDMs demethylate histones pa …
The significant predisposed genes with functional variants of Y-chromomere are strongly connected with spermatogenic failure ( …
Reproductive outcomes and Y chromosome instability in radiation-exposed male workers in cardiac catheterization laboratory.
Andreassi MG, Borghini A, Vecoli C, Piccaluga E, Guagliumi G, Del Greco M, Gaita F, Picano E. Andreassi MG, et al. Environ Mol Mutagen. 2020 Mar;61(3):361-368. doi: 10.1002/em.22341. Epub 2019 Oct 25. Environ Mol Mutagen. 2020. PMID: 31605552
An increased copy number variation (CNV) in azoospermia factor region c (AZFc) of the Y chromosome is a marker of spermatogenic failure, previously associated with radiation exposure. ...Exposed workers had a higher prevalence of low birth weight in offspring (Group …
An increased copy number variation (CNV) in azoospermia factor region c (AZFc) of the Y chromosome is a marker of spermatogenic fa …
Actionable secondary findings following exome sequencing of 836 non-obstructive azoospermia cases and their value in patient management.
Kasak L, Lillepea K, Nagirnaja L, Aston KI, Schlegel PN, Gonçalves J, Carvalho F, Moreno-Mendoza D, Almstrup K, Eisenberg ML, Jarvi KA, O'Bryan MK, Lopes AM, Conrad DF; GEMINI Consortium; Punab M, Laan M. Kasak L, et al. Hum Reprod. 2022 Jun 30;37(7):1652-1663. doi: 10.1093/humrep/deac100. Hum Reprod. 2022. PMID: 35535697 Free PMC article.
WIDER IMPLICATIONS OF THE FINDINGS: For the first time, this study analyzed medically actionable SFs in men with spermatogenic failure. With the evolving process to incorporate ES into routine andrology practice for molecular diagnostic purposes, additional assessme …
WIDER IMPLICATIONS OF THE FINDINGS: For the first time, this study analyzed medically actionable SFs in men with spermatogenic fai …
Recovery of sperm production following the cessation of gossypol treatment: a two-centre study in China.
Meng GD, Zhu JC, Chen ZW, Wong LT, Zhang GY, Hu YZ, Ding JH, Wang XH, Qian SZ, Wang C, et al. Meng GD, et al. Int J Androl. 1988 Feb;11(1):1-11. doi: 10.1111/j.1365-2605.1988.tb01211.x. Int J Androl. 1988. PMID: 3356480
In those with sperm present the geometric mean concentration and total sperm count were 8.3 X 10(6)/ml and 30.7 X 10(6), respectively. Twenty-eight men (61%) recovered to a defined threshold of spermatogenic function (sperm concentration greater than or equal to 20 …
In those with sperm present the geometric mean concentration and total sperm count were 8.3 X 10(6)/ml and 30.7 X 10(6), respectively …
13 results