Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 1
2001 2
2002 2
2006 2
2007 4
2009 1
2010 1
2011 1
2012 1
2014 2
2015 2
2016 2
2017 1
2018 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

24 results

Results by year

Filters applied: . Clear all
Page 1
Spinocerebellar ataxia type 6.
Solodkin A, Gomez CM. Solodkin A, et al. Handb Clin Neurol. 2012;103:461-73. doi: 10.1016/B978-0-444-51892-7.00029-2. Handb Clin Neurol. 2012. PMID: 21827907 Review.
The autosomal dominant spinocerebellar ataxias (SCA) are a genetically heterogeneous group of neurodegenerative disorders characterized by progressive motor incoordination, in some cases with ataxia alone and in others in association with additional progressive neurological defic …
The autosomal dominant spinocerebellar ataxias (SCA) are a genetically heterogeneous group of neurodegenerative disorders characterized by p …
The P/Q-type voltage-dependent calcium channel: a therapeutic target in spinocerebellar ataxia type 6.
Gazulla J, Tintoré M. Gazulla J, et al. Acta Neurol Scand. 2007 May;115(5):356-63. doi: 10.1111/j.1600-0404.2006.00752.x. Acta Neurol Scand. 2007. PMID: 17489948 Review.
BACKGROUND: Voltage-dependent calcium channels (VDCCs) are heteromultimeric complexes that mediate calcium influx into cells; the alpha 1A subunit is the pore-forming subunit specific to the neuronal P/Q-type VDCCs. Spinocerebellar ataxia type 6 (SCA 6 …
BACKGROUND: Voltage-dependent calcium channels (VDCCs) are heteromultimeric complexes that mediate calcium influx into cells; the alpha 1A s …
Metabolic characterization of spinocerebellar ataxia type 6.
Soong B, Liu R, Wu L, Lu Y, Lee H. Soong B, et al. Arch Neurol. 2001 Feb;58(2):300-4. doi: 10.1001/archneur.58.2.300. Arch Neurol. 2001. PMID: 11176970 Clinical Trial.
BACKGROUND: Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disorder characterized by slowly progressive ataxia and dysarthria. The mutational basis is an expanded CAG repeat sequence within the coding regions of the CACNL1A4 gene. Basic …
BACKGROUND: Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disorder characterized by slowly progres …
Spinocerebellar ataxia type 6 (SCA6): clinical pilot trial with gabapentin.
Nakamura K, Yoshida K, Miyazaki D, Morita H, Ikeda S. Nakamura K, et al. J Neurol Sci. 2009 Mar 15;278(1-2):107-11. doi: 10.1016/j.jns.2008.12.017. Epub 2009 Jan 21. J Neurol Sci. 2009. PMID: 19157422 Free article. Clinical Trial.
The clinical effect of the GABAergic drug gabapentin was evaluated in 11 patients with spinocerebellar ataxia type 6 (SCA6). ...As a whole, the efficacy of gabapentin was not statistically confirmed in the 4-week trial because of the vari …
The clinical effect of the GABAergic drug gabapentin was evaluated in 11 patients with spinocerebellar ataxia type …
Impaired Spatio-Temporal Predictive Motor Timing Associated with Spinocerebellar Ataxia Type 6.
Broersen R, Onuki Y, Abdelgabar AR, Owens CB, Picard S, Willems J, Boele HJ, Gazzola V, Van der Werf YD, De Zeeuw CI. Broersen R, et al. PLoS One. 2016 Aug 29;11(8):e0162042. doi: 10.1371/journal.pone.0162042. eCollection 2016. PLoS One. 2016. PMID: 27571363 Free PMC article. Clinical Trial.
In the present study we sought to further investigate the cerebellar contribution to predictive and reactive motor timing, as well as to learning of sequential order and temporal intervals in these tasks. We tested patients with spinocerebellar ataxia type …
In the present study we sought to further investigate the cerebellar contribution to predictive and reactive motor timing, as well as to lea …
Distinct cerebellar regions related to motor and cognitive performance in SCA6 patients.
Rentiya Z, Khan NS, Ergun E, Ying SH, Desmond JE. Rentiya Z, et al. Neuropsychologia. 2017 Dec;107:25-30. doi: 10.1016/j.neuropsychologia.2017.10.036. Epub 2017 Oct 31. Neuropsychologia. 2017. PMID: 29100951 Free PMC article.
OBJECTIVE: To demonstrate a correlation between anatomic regional changes in Spinocerebellar Ataxia type 6 (SCA6) patients and measures of cognitive performance on neuropsychological tests. ...RESULTS: Compared to controls, SCA6 patients exhibited sign …
OBJECTIVE: To demonstrate a correlation between anatomic regional changes in Spinocerebellar Ataxia type 6 (SCA6 …
Cerebellar Degeneration Increases Visual Influence on Dynamic Estimates of Verticality.
Dakin CJ, Peters A, Giunti P, Day BL. Dakin CJ, et al. Curr Biol. 2018 Nov 19;28(22):3589-3598.e3. doi: 10.1016/j.cub.2018.09.049. Epub 2018 Nov 1. Curr Biol. 2018. PMID: 30393031 Free article.
Here we show that a perceptual disturbance of verticality is indeed present in people with a genetically determined and pure form of cerebellar degeneration (spinocerebellar ataxia type 6; SCA 6), but is only revealed under dynamic visual conditions. P …
Here we show that a perceptual disturbance of verticality is indeed present in people with a genetically determined and pure form of cerebel …
Comparison of cerebellar ataxias: A three-year prospective longitudinal assessment.
Lee YC, Liao YC, Wang PS, Lee IH, Lin KP, Soong BW. Lee YC, et al. Mov Disord. 2011 Sep;26(11):2081-7. doi: 10.1002/mds.23809. Epub 2011 May 28. Mov Disord. 2011. PMID: 21626567
Severity of ataxia was assessed in 238 patients with spinocerebellar ataxia type 2, spinocerebellar ataxia type 3, spinocerebellar ataxia type 6, spinocerebellar ataxia type 17, multiple system atrophy-cerebellar variant, or Gerstman-Straussler-Scheink …
Severity of ataxia was assessed in 238 patients with spinocerebellar ataxia type 2, spinocerebellar ataxia type 3, spinocerebellar …
The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit.
Gazulla J, Tintoré MA. Gazulla J, et al. Med Hypotheses. 2007;68(1):131-6. doi: 10.1016/j.mehy.2006.06.014. Epub 2006 Aug 8. Med Hypotheses. 2007. PMID: 16899342
Their highest levels of expression are found in the Purkinje cell layer of the cerebellum, and in the hippocampus. Spinocerebellar ataxia type 6 (SCA 6) is an autosomal dominant cerebellar degeneration that shares neuropathological findings with late-o …
Their highest levels of expression are found in the Purkinje cell layer of the cerebellum, and in the hippocampus. Spinocerebellar …
24 results