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Quoted phrase not found in phrase index: "Sporadic Cylindroma"
Page 1
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J. Zaballos P, et al. Dermatol Clin. 2018 Oct;36(4):397-412. doi: 10.1016/j.det.2018.05.007. Epub 2018 Aug 16. Dermatol Clin. 2018. PMID: 30201149 Review.
Cutaneous adnexal tumors include lesions with apocrine, eccrine, follicular, sebaceous, and mixed differentiation. Most are benign and sporadic, although malignant forms are occasionally observed and some cases develop in the setting of inherited syndromes. ...Most …
Cutaneous adnexal tumors include lesions with apocrine, eccrine, follicular, sebaceous, and mixed differentiation. Most are benign and sp …
SOX11: a potentially useful marker in surgical pathology: a systematic analysis of SOX11 expression in epithelial and non-epithelial tumours.
Xu S, Dong Y, Huo Z, Yu L, Xue J, Wang G, Duan Y. Xu S, et al. Histopathology. 2019 Feb;74(3):391-405. doi: 10.1111/his.13757. Epub 2018 Dec 2. Histopathology. 2019. PMID: 30221780
SOX11 was consistently expressed in all neuroectodermal tumours with neural differentiation, as well as in immature teratomas revealing neurogenesis. Less frequently, SOX11 expression was observed in only 50% of astrocytomas and 24% of malignant peripheral nerve sheath tum …
SOX11 was consistently expressed in all neuroectodermal tumours with neural differentiation, as well as in immature teratomas revealing neur …
The MYB-NFIB gene fusion-a novel genetic link between adenoid cystic carcinoma and dermal cylindroma.
Fehr A, Kovács A, Löning T, Frierson H Jr, van den Oord J, Stenman G. Fehr A, et al. J Pathol. 2011 Jul;224(3):322-7. doi: 10.1002/path.2909. Epub 2011 May 27. J Pathol. 2011. PMID: 21618541
We have recently shown that the recurrent t(6;9)(q22 23;p23 24) translocation in adenoid cystic carcinoma (ACC) of the breast and head and neck results in a fusion of the two transcription factor genes MYB and NFIB. Here we demonstrate, for the first time, th …
We have recently shown that the recurrent t(6;9)(q22 23;p23 24) translocation in adenoid cystic carcinoma (ACC) of the …
A clinicopathologic and molecular biologic study of patients presenting with few adnexal tumors (two to four) from the morphological spectrum of Brooke-Spiegler syndrome.
Kacerovska D, Vanecek T, Spagnolo DV, Bisceglia M, Zelger B, Michal M, Kazakov DV. Kacerovska D, et al. Am J Dermatopathol. 2013 Feb;35(1):19-24. doi: 10.1097/DAD.0b013e318255dd37. Am J Dermatopathol. 2013. PMID: 22588548
We report 11 individuals, each presenting with few (2-4) adnexal neoplasms histologically confirmed as belonging to the spectrum of lesions typical for Brooke-Spiegler syndrome (BSS) and/or multiple familial trichoepitheliomas. These include spiradenoma, cylindroma, spirad …
We report 11 individuals, each presenting with few (2-4) adnexal neoplasms histologically confirmed as belonging to the spectrum of lesions …
Identification of the familial cylindromatosis tumour-suppressor gene.
Bignell GR, Warren W, Seal S, Takahashi M, Rapley E, Barfoot R, Green H, Brown C, Biggs PJ, Lakhani SR, Jones C, Hansen J, Blair E, Hofmann B, Siebert R, Turner G, Evans DG, Schrander-Stumpel C, Beemer FA, van Den Ouweland A, Halley D, Delpech B, Cleveland MG, Leigh I, Leisti J, Rasmussen S. Bignell GR, et al. Nat Genet. 2000 Jun;25(2):160-5. doi: 10.1038/76006. Nat Genet. 2000. PMID: 10835629
Here we have identified CYLD by detecting germline mutations in 21 cylindromatosis families and somatic mutations in 1 sporadic and 5 familial cylindromas. All mutations predict truncation or absence of the encoded protein. ...
Here we have identified CYLD by detecting germline mutations in 21 cylindromatosis families and somatic mutations in 1 sporadic and 5 …
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.
Rajan N, Elliott R, Clewes O, Mackay A, Reis-Filho JS, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A. Rajan N, et al. Oncogene. 2011 Oct 13;30(41):4243-60. doi: 10.1038/onc.2011.133. Epub 2011 May 9. Oncogene. 2011. PMID: 21552290 Free PMC article.
Immunohistochemical analysis of a tumour microarray showed strong membranous TRKB and TRKC staining in cylindromas, as well as elevated levels of ERK phosphorylation and BCL2 expression. Membranous TRKC overexpression was also observed in 70% of sporadic BCCs …
Immunohistochemical analysis of a tumour microarray showed strong membranous TRKB and TRKC staining in cylindromas, as well as elevat …
Salivary gland type nasopharyngeal carcinoma: a histologic, immunohistochemical, and Epstein-Barr virus study of 15 cases including a psammomatous mucoepidermoid carcinoma.
Kuo T, Tsang NM. Kuo T, et al. Am J Surg Pathol. 2001 Jan;25(1):80-6. doi: 10.1097/00000478-200101000-00009. Am J Surg Pathol. 2001. PMID: 11145255
Others were adenoid cystic carcinomas and various adenocarcinomas, including a papillary adenocarcinoma. A composite tumor of adenocarcinoma and undifferentiated carcinoma was also observed. The tumors were positive for AE1 and CK19 and generally negat …
Others were adenoid cystic carcinomas and various adenocarcinomas, including a papillary adenocarcinoma. A composite tumor of …
Facial mimetic, cosmetic, and functional standardized assessment of the facial artery musculomucosal (FAMM) flap.
Jowett N, Hadlock TA, Sela E, Toth M, Knecht R, Lörincz BB. Jowett N, et al. Auris Nasus Larynx. 2017 Apr;44(2):220-226. doi: 10.1016/j.anl.2016.07.004. Epub 2016 Jul 21. Auris Nasus Larynx. 2017. PMID: 27452415
Use of the FAMM-flap in oral cavity reconstruction remains sporadic. This case series describes our newly developed standardized assessment of this flap in a floor of mouth (FOM) reconstructive setting. ...Oral competence remained intact, tongue mobility was good to excell …
Use of the FAMM-flap in oral cavity reconstruction remains sporadic. This case series describes our newly developed standardized asse …
Poorly differentiated thyroid carcinoma mimicking adenoid cystic carcinoma on aspiration cytology: a case report.
Malhotra P, Deewan U, Krishnani N. Malhotra P, et al. Acta Cytol. 2009 Sep-Oct;53(5):591-3. doi: 10.1159/000325391. Acta Cytol. 2009. PMID: 19798891
This pattern in fine needle aspiration cytology (FNAC) of thyroid malignancies is rare. Sporadic reports of papillary and follicular carcinoma with adenoid cystic pattern are described in the literature. ...FNAC smears consisted predominantly of cells …
This pattern in fine needle aspiration cytology (FNAC) of thyroid malignancies is rare. Sporadic reports of papillary and follicular …
The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas.
Biggs PJ, Chapman P, Lakhani SR, Burn J, Stratton MR. Biggs PJ, et al. Oncogene. 1996 Mar 21;12(6):1375-7. Oncogene. 1996. PMID: 8649842
No loss of heterozygosity (LOH) was detected other than at loci on chromosome 16q. This observation suggests that the cyld1 gene may be the only tumour suppressor gene implicated in the development of cylindromas. We have also demonstrated LOH using markers on chrom …
No loss of heterozygosity (LOH) was detected other than at loci on chromosome 16q. This observation suggests that the cyld1 gene may …