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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1983 1
1985 2
1988 1
1992 1
1993 2
1994 1
1995 1
1996 1
1997 1
1998 5
1999 4
2000 3
2001 3
2002 7
2003 5
2004 7
2005 10
2006 5
2007 7
2008 3
2009 6
2010 7
2011 4
2012 6
2013 5
2014 3
2015 10
2016 10
2017 9
2018 8
2019 8
2020 5
2021 1
2022 2
2023 3
2024 2

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144 results

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Page 1
Allergic bronchopulmonary aspergillosis.
Patel G, Greenberger PA. Patel G, et al. Allergy Asthma Proc. 2019 Nov 1;40(6):421-424. doi: 10.2500/aap.2019.40.4262. Allergy Asthma Proc. 2019. PMID: 31690385 Review.
Prednisone is indicated to clear pulmonary infiltrates, and a usual course is for 3 months. Itraconazole and voriconazole are adjunctive, and drug-drug interactions must be considered because azoles decrease elimination of various medications. ...
Prednisone is indicated to clear pulmonary infiltrates, and a usual course is for 3 months. Itraconazole and voriconazole are adjunct …
Biomarkers and asthma management: an update.
Bayes HK, Cowan DC. Bayes HK, et al. Curr Opin Allergy Clin Immunol. 2016 Jun;16(3):210-7. doi: 10.1097/ACI.0000000000000263. Curr Opin Allergy Clin Immunol. 2016. PMID: 27057795 Review.
This review provides an update on available data regarding asthma biomarkers with focus on their utility for prediction of response to steroidal and new biological therapies. RECENT FINDINGS: Blood eosinophils are a biomarker with acceptable accuracy as a surrogate for spu …
This review provides an update on available data regarding asthma biomarkers with focus on their utility for prediction of response t …
Eosinophil-derived IL-13 promotes emphysema.
Doyle AD, Mukherjee M, LeSuer WE, Bittner TB, Pasha SM, Frere JJ, Neely JL, Kloeber JA, Shim KP, Ochkur SI, Ho T, Svenningsen S, Wright BL, Rank MA, Lee JJ, Nair P, Jacobsen EA. Doyle AD, et al. Eur Respir J. 2019 May 30;53(5):1801291. doi: 10.1183/13993003.01291-2018. Print 2019 May. Eur Respir J. 2019. PMID: 30728205 Free PMC article.
In chronic airways disease patients, lung eosinophilia was associated with elevated MMP-12 levels, which was a predictor of emphysema. These findings suggest an underappreciated mechanism by which eosinophils contribute to the pathologies associated with asthma and COPD... …
In chronic airways disease patients, lung eosinophilia was associated with elevated MMP-12 levels, which was a predictor of emphysema …
Lessons learned from clinical trials of asthma.
Greenberger PA. Greenberger PA. Allergy Asthma Proc. 2019 Nov 1;40(6):410-413. doi: 10.2500/aap.2019.40.4259. Allergy Asthma Proc. 2019. PMID: 31690382 Review.
Alternatively, in adults, the lower baseline FEV(1) (2.3 L [74% predicted] versus 2.5 L [78% predicted]) identified patients more likely to have a future exacerbation compared with patients who were not having an exacerbation. ...
Alternatively, in adults, the lower baseline FEV(1) (2.3 L [74% predicted] versus 2.5 L [78% predicted]) identified patients m …
Eosinophils in COPD-Current Concepts and Clinical Implications.
Mycroft K, Krenke R, Górska K. Mycroft K, et al. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2565-2574. doi: 10.1016/j.jaip.2020.03.017. Epub 2020 Apr 3. J Allergy Clin Immunol Pract. 2020. PMID: 32251737 Review.
Nevertheless, in several trials, blood eosinophil count appeared to predict good response to inhaled corticosteroids However, biologics targeting eosinophils do not appear to be effective in COPD. ...Then, we discuss the use of blood eosinophil count in COPD in relation to …
Nevertheless, in several trials, blood eosinophil count appeared to predict good response to inhaled corticosteroids However, biologi …
Asthma biomarkers in sputum.
Spahn JD. Spahn JD. Immunol Allergy Clin North Am. 2012 Aug;32(3):387-99. doi: 10.1016/j.iac.2012.06.004. Immunol Allergy Clin North Am. 2012. PMID: 22877617 Review.
Targeted therapy of bronchitis in obstructive airway diseases.
Dasgupta A, Neighbour H, Nair P. Dasgupta A, et al. Pharmacol Ther. 2013 Dec;140(3):213-22. doi: 10.1016/j.pharmthera.2013.07.001. Epub 2013 Jul 8. Pharmacol Ther. 2013. PMID: 23845862 Review.
Neutrophilic bronchitis which is a non-Th2 driven disease is generally a predictor of response to antibiotics and may be a predictor to therapies targeted at pathways that lead to neutrophil recruitment such as IL-8 (eg anti-CXCR2), IL-17 (eg anti-IL17) etc. ...
Neutrophilic bronchitis which is a non-Th2 driven disease is generally a predictor of response to antibiotics and may be a predict …
Rheology predicts sputum eosinophilia in patients with muco-obstructive lung diseases.
Volpato M, Vialaret J, Hirtz C, Petit A, Suehs C, Patarin J, Matzner-Lober E, Vachier I, Molinari N, Bourdin A, Charriot J. Volpato M, et al. Biochem Biophys Res Commun. 2022 Sep 24;622:64-71. doi: 10.1016/j.bbrc.2022.07.025. Epub 2022 Jul 11. Biochem Biophys Res Commun. 2022. PMID: 35843096
Among them, 10 had asthma, 14 COPD and 24 non-CF bronchiectasis (NCFB). The critical stress threshold sigmac predicted a sputum eosinophilia superior to 1.25% with 89.19% accuracy (AUC = 0.8762). ...G' and G" were significantly higher in asthma patients (G' = 14.49[7.18-25 …
Among them, 10 had asthma, 14 COPD and 24 non-CF bronchiectasis (NCFB). The critical stress threshold sigmac predicted a sputum eosin …
Clinical applications of induced sputum.
Brightling CE. Brightling CE. Chest. 2006 May;129(5):1344-8. doi: 10.1378/chest.129.5.1344. Chest. 2006. PMID: 16685028 Review.
To date, the identification of sputum eosinophilia has the greatest clinical value as this predicts a favorable response to corticosteroids and can therefore guide treatment. ...
To date, the identification of sputum eosinophilia has the greatest clinical value as this predicts a favorable response to corticost …
Clinical phenotypes of asthma should link up with disease mechanisms.
Chung KF, Adcock IM. Chung KF, et al. Curr Opin Allergy Clin Immunol. 2015 Feb;15(1):56-62. doi: 10.1097/ACI.0000000000000134. Curr Opin Allergy Clin Immunol. 2015. PMID: 25504141 Free article. Review.
Sputum eosinophilia can predict therapeutic responses to T-helper type 2 cytokine blockade. Further molecular phenotyping or endotyping of asthma will be necessary to determine new treatment strategies. Low T-helper type 2 expression may be predictive of poor therap …
Sputum eosinophilia can predict therapeutic responses to T-helper type 2 cytokine blockade. Further molecular phenotyping or endotypi …
144 results