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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1971 1
1972 1
1975 1
1976 1
1978 1
1981 2
1985 1
1986 1
1988 6
1989 1
1990 5
1991 4
1992 4
1993 6
1994 7
1995 2
1996 8
1997 4
1998 3
1999 7
2000 5
2001 7
2002 12
2003 10
2004 14
2005 12
2006 24
2007 20
2008 26
2009 22
2010 21
2011 20
2012 26
2013 22
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2016 31
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2022 32
2023 24
2024 10

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506 results

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Page 1
IPNA clinical practice recommendations for the diagnosis and management of children with steroid-resistant nephrotic syndrome.
Trautmann A, Vivarelli M, Samuel S, Gipson D, Sinha A, Schaefer F, Hui NK, Boyer O, Saleem MA, Feltran L, Müller-Deile J, Becker JU, Cano F, Xu H, Lim YN, Smoyer W, Anochie I, Nakanishi K, Hodson E, Haffner D; International Pediatric Nephrology Association. Trautmann A, et al. Pediatr Nephrol. 2020 Aug;35(8):1529-1561. doi: 10.1007/s00467-020-04519-1. Epub 2020 May 7. Pediatr Nephrol. 2020. PMID: 32382828 Free PMC article. Review.
Patients who do not achieve complete remission within 4-6 weeks of glucocorticoid treatment have steroid-resistant nephrotic syndrome (SRNS). In 10-30% of steroid-resistant patients, mutations in podocyte-associated genes can be detected, whereas an un …
Patients who do not achieve complete remission within 4-6 weeks of glucocorticoid treatment have steroid-resistant nephroti
Childhood nephrotic syndrome.
Vivarelli M, Gibson K, Sinha A, Boyer O. Vivarelli M, et al. Lancet. 2023 Sep 2;402(10404):809-824. doi: 10.1016/S0140-6736(23)01051-6. Lancet. 2023. PMID: 37659779 Review.
Most children respond to a cycle of oral steroids, and are defined as having steroid-sensitive nephrotic syndrome. Among the children who do not respond, defined as having steroid-resistant nephrotic syndrome, most respond to second-line immunosuppress …
Most children respond to a cycle of oral steroids, and are defined as having steroid-sensitive nephrotic syndrome. Among the children who do …
Nephrotic syndrome.
Sinha A, Bagga A. Sinha A, et al. Indian J Pediatr. 2012 Aug;79(8):1045-55. doi: 10.1007/s12098-012-0776-y. Epub 2012 May 30. Indian J Pediatr. 2012. PMID: 22644544 Review.
The central role of the podocyte in causing proteinuria is confirmed by the observation of mutations in key podocyte proteins in steroid resistant nephrotic syndrome and experimental evidence of altered podocyte signaling and cytoskeletal organization. …
The central role of the podocyte in causing proteinuria is confirmed by the observation of mutations in key podocyte proteins in steroid
Biologics in steroid resistant nephrotic syndrome in childhood: review and new hypothesis-driven treatment.
Angeletti A, Bruschi M, Kajana X, La Porta E, Spinelli S, Caridi G, Lugani F, Verrina EE, Ghiggeri GM. Angeletti A, et al. Front Immunol. 2023 Aug 29;14:1213203. doi: 10.3389/fimmu.2023.1213203. eCollection 2023. Front Immunol. 2023. PMID: 37705972 Free PMC article. Review.
Steroids still represent the cornerstone of therapy achieving remission in 75-90% of the cases The remaining part result as steroid resistant nephrotic syndrome, characterized by the elevated risk of developing end stage kidney disease and frequently p …
Steroids still represent the cornerstone of therapy achieving remission in 75-90% of the cases The remaining part result as steroid
Management of steroid-resistant nephrotic syndrome in children and adolescents.
Tullus K, Webb H, Bagga A. Tullus K, et al. Lancet Child Adolesc Health. 2018 Dec;2(12):880-890. doi: 10.1016/S2352-4642(18)30283-9. Epub 2018 Oct 18. Lancet Child Adolesc Health. 2018. PMID: 30342869 Review.
Patients who do not show remission after 4 weeks' treatment with daily prednisolone are considered to have steroid-resistant nephrotic syndrome (SRNS). Renal histology in most patients shows presence of focal segmental glomerulosclerosis, minimal chang …
Patients who do not show remission after 4 weeks' treatment with daily prednisolone are considered to have steroid-resistant
Rituximab therapy for refractory steroid-resistant nephrotic syndrome in children.
Kamei K, Ishikura K, Sako M, Ito S, Nozu K, Iijima K. Kamei K, et al. Pediatr Nephrol. 2020 Jan;35(1):17-24. doi: 10.1007/s00467-018-4166-1. Epub 2018 Dec 18. Pediatr Nephrol. 2020. PMID: 30564879 Review.
Patients with steroid-resistant nephrotic syndrome (SRNS) who develop resistance to immunosuppressive agents, defined as refractory SRNS, have poor renal outcomes. ...According to previous case reports, 50.4% of patients with refractory SRNS showed …
Patients with steroid-resistant nephrotic syndrome (SRNS) who develop resistance to immunosuppressive agents, de …
Treatment of nephrotic syndrome: going beyond immunosuppressive therapy.
Zhao J, Liu Z. Zhao J, et al. Pediatr Nephrol. 2020 Apr;35(4):569-579. doi: 10.1007/s00467-019-04225-7. Epub 2019 Mar 23. Pediatr Nephrol. 2020. PMID: 30904930 Review.
Unfortunately, there is no "one-size-fits-all" approach for precise patient stratification and treatment when facing the huge challenges posed by steroid-resistant nephrotic syndrome (SRNS). But genomic medicine has brought a glimmer of light, and the …
Unfortunately, there is no "one-size-fits-all" approach for precise patient stratification and treatment when facing the huge challenges pos …
Genetics of childhood steroid-sensitive nephrotic syndrome.
Karp AM, Gbadegesin RA. Karp AM, et al. Pediatr Nephrol. 2017 Sep;32(9):1481-1488. doi: 10.1007/s00467-016-3456-8. Epub 2016 Jul 29. Pediatr Nephrol. 2017. PMID: 27470160 Free PMC article. Review.
The pathogenesis of childhood-onset nephrotic syndrome (NS), disparity in incidence of NS among races, and variable responses to therapies in children with NS have defied explanation to date. In the last 20 years over 50 genetic causes of steroid-resistant nephro
The pathogenesis of childhood-onset nephrotic syndrome (NS), disparity in incidence of NS among races, and variable responses to therapies i …
Treatment of steroid-resistant nephrotic syndrome in the genomic era.
Bensimhon AR, Williams AE, Gbadegesin RA. Bensimhon AR, et al. Pediatr Nephrol. 2019 Nov;34(11):2279-2293. doi: 10.1007/s00467-018-4093-1. Epub 2018 Oct 2. Pediatr Nephrol. 2019. PMID: 30280213 Free PMC article. Review.
The pathogenesis of steroid-resistant nephrotic syndrome (SRNS) is not completely known. ...
The pathogenesis of steroid-resistant nephrotic syndrome (SRNS) is not completely known. ...
506 results