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Stiff-man syndrome: an overview.
Stayer C, Meinck HM. Stayer C, et al. Neurologia. 1998 Feb;13(2):83-8. Neurologia. 1998. PMID: 9578675 Review.
Fluctuating stiffness and paroxysmal spasms of the trunk and legs are the primary features of stiff-man syndrome and it's variants, progressive encephalomyelopathy with rigidity and myoclonus (PERM) and stiff-leg syndrome. ...The diagnosis is based on clinica …
Fluctuating stiffness and paroxysmal spasms of the trunk and legs are the primary features of stiff-man syndrome and it …
Stiff-person syndrome: insights into a complex autoimmune disorder.
Baizabal-Carvallo JF, Jankovic J. Baizabal-Carvallo JF, et al. J Neurol Neurosurg Psychiatry. 2015 Aug;86(8):840-8. doi: 10.1136/jnnp-2014-309201. Epub 2014 Dec 15. J Neurol Neurosurg Psychiatry. 2015. PMID: 25511790 Review.
Antibodies directed against GABA(A) receptor-associated protein, and the glycine-alpha1 receptor can also be observed. Paraneoplastic SPS is commonly associated with antiamphiphysin antibodies and breast cancer. ...
Antibodies directed against GABA(A) receptor-associated protein, and the glycine-alpha1 receptor can also be observed. Paraneoplastic …
Stiff-man syndrome and variants: clinical course, treatments, and outcomes.
McKeon A, Robinson MT, McEvoy KM, Matsumoto JY, Lennon VA, Ahlskog JE, Pittock SJ. McKeon A, et al. Arch Neurol. 2012 Feb;69(2):230-8. doi: 10.1001/archneurol.2011.991. Arch Neurol. 2012. PMID: 22332190
BACKGROUND: Little information is available about the incidence of stiff-man syndrome (SMS) (the classic form or its variants) or about long-term treatment responses and outcomes. OBJECTIVE: To comprehensively describe the characteristics of a cohort of patie …
BACKGROUND: Little information is available about the incidence of stiff-man syndrome (SMS) (the classic form or its va …
Rheumatological symptoms due to retinoids.
Kaplan G, Haettich B. Kaplan G, et al. Baillieres Clin Rheumatol. 1991 Apr;5(1):77-97. doi: 10.1016/s0950-3579(05)80297-3. Baillieres Clin Rheumatol. 1991. PMID: 2070429 Review.
Retinoids may be responsible for muscular damage and an abnormality of muscular tone resembling the stiff-man syndrome. Some cases of necrotizing vasculitis and three cases of Wegener's granulomatosis have been observed in patients treated with retinoi …
Retinoids may be responsible for muscular damage and an abnormality of muscular tone resembling the stiff-man syndrome. …
Amphiphysin autoimmunity: paraneoplastic accompaniments.
Pittock SJ, Lucchinetti CF, Parisi JE, Benarroch EE, Mokri B, Stephan CL, Kim KK, Kilimann MW, Lennon VA. Pittock SJ, et al. Ann Neurol. 2005 Jul;58(1):96-107. doi: 10.1002/ana.20529. Ann Neurol. 2005. PMID: 15984030
Coexisting paraneoplastic autoantibodies, identified in 74% of patients, predicted a common neoplasm and indicated other neuronal autoantigen targets that plausibly explained several neurological manifestations; for example, P/Q-type Ca(2+)-channel antibody with Lambert-Ea …
Coexisting paraneoplastic autoantibodies, identified in 74% of patients, predicted a common neoplasm and indicated other neuronal aut …
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome.
Solimena M, Folli F, Aparisi R, Pozza G, De Camilli P. Solimena M, et al. N Engl J Med. 1990 May 31;322(22):1555-60. doi: 10.1056/NEJM199005313222202. N Engl J Med. 1990. PMID: 2135382 Free article.
Stiff-man syndrome is a rare disorder of the central nervous system of unknown pathogenesis. ...GAD is an enzyme selectively concentrated in neurons secreting the neurotransmitter gamma-aminobutyric acid (GABA) and in pancreatic beta cells. We subsequently …
Stiff-man syndrome is a rare disorder of the central nervous system of unknown pathogenesis. ...GAD is an enzyme select …
GAD autoantibodies in IDDM, stiff-man syndrome, and autoimmune polyendocrine syndrome type I recognize different epitopes.
Björk E, Velloso LA, Kämpe O, Karlsson FA. Björk E, et al. Diabetes. 1994 Jan;43(1):161-5. doi: 10.2337/diab.43.1.161. Diabetes. 1994. PMID: 7505244
Glutamic acid decarboxylase (GAD) is a major islet cell autoantigen in insulin-dependent diabetes mellitus (IDDM), and autoantibodies are found in high frequencies in patients with recent-onset IDDM, stiff-man syndrome (SMS), and autoimmune polyendocrine synd …
Glutamic acid decarboxylase (GAD) is a major islet cell autoantigen in insulin-dependent diabetes mellitus (IDDM), and autoantibodies are fo …
Steroid-responsive and dependent stiff-man syndrome: a clinical and electrophysiological study of two cases.
Piccolo G, Cosi V, Zandrini C, Moglia A. Piccolo G, et al. Ital J Neurol Sci. 1988 Dec;9(6):559-66. doi: 10.1007/BF02337009. Ital J Neurol Sci. 1988. PMID: 3225166
Two female patients with the typical clinical and electrophysiological features of the stiff-man syndrome, both responded to steroid treatment. ACTH infusion produced an immediate clinical relief of muscle contracture and cramps, with parallel marked reductio …
Two female patients with the typical clinical and electrophysiological features of the stiff-man syndrome, both respond …
IGIV in neurology--evidence and recommendations.
Bril V, Allenby K, Midroni G, O'Connor PW, Vajsar J. Bril V, et al. Can J Neurol Sci. 1999 May;26(2):139-52. Can J Neurol Sci. 1999. PMID: 10352875 Review.
The usefulness of IGIV in neurology can be described by a "combined score" based on evidence quality and strength of impact. Combined scores ranged from A+ (strongly recommended) to C (recommended as a last resort). The following clinical recommendations are made: I …
The usefulness of IGIV in neurology can be described by a "combined score" based on evidence quality and strength of impact. Combined …
Stiff person syndrome with Anti-GAD65 antibodies within the national veterans affairs health administration.
Galli JR, Austin SD, Greenlee JE, Clardy SL. Galli JR, et al. Muscle Nerve. 2018 Dec;58(6):801-804. doi: 10.1002/mus.26338. Epub 2018 Nov 20. Muscle Nerve. 2018. PMID: 30192027
Ten of 15 patients received intravenous immunoglobulin, with a majority demonstrating stable or improved modified Rankin scores. DISCUSSION: This investigation was a large North American epidemiological study of SPS with predominantly male patients. ...
Ten of 15 patients received intravenous immunoglobulin, with a majority demonstrating stable or improved modified Rankin scores. DISC …
32 results