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2,188 results

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Page 1
Sulfonamide Allergies.
Giles A, Foushee J, Lantz E, Gumina G. Giles A, et al. Pharmacy (Basel). 2019 Sep 11;7(3):132. doi: 10.3390/pharmacy7030132. Pharmacy (Basel). 2019. PMID: 31514363 Free PMC article. Review.
In the general population, approximately 3-8% of patients are reported to experience a sulfonamide allergy. Sulfonamide allergies can result in various physical manifestations; however, rash is reported as the most frequently observed. ...This article describes the …
In the general population, approximately 3-8% of patients are reported to experience a sulfonamide allergy. Sulfonamide allerg …
Sulfonamide hypersensitivity.
Slatore CG, Tilles SA. Slatore CG, et al. Immunol Allergy Clin North Am. 2004 Aug;24(3):477-90, vii. doi: 10.1016/j.iac.2004.03.011. Immunol Allergy Clin North Am. 2004. PMID: 15242722 Review.
Sulfonamide antibiotics can result in a wide variety of hypersensitivity reactions. ...Whether the sulfa moiety confers a risk of cross-reaction is controversial. The preponderance of available evidence suggests that sulfonamide antibiotics probably do not cross-rea
Sulfonamide antibiotics can result in a wide variety of hypersensitivity reactions. ...Whether the sulfa moiety confers a risk of cro
N-(12-Amino-9,10-di-hydro-9,10-ethano-anthracen-11-yl)-4-methyl-benzene-sulfonamide.
Mague JT, Abdel-Aziz AA, El-Azab AS, El-Sherbeny MA. Mague JT, et al. Acta Crystallogr Sect E Struct Rep Online. 2014 Feb 5;70(Pt 3):o248-9. doi: 10.1107/S1600536814002189. eCollection 2014 Mar 1. Acta Crystallogr Sect E Struct Rep Online. 2014. PMID: 24764968 Free PMC article.
The title compound, C23H22N2O2S, crystallizes with the 4-methyl-benzene-sulfonamide entity oriented towards the center of the bridgehead C atoms with a C-N-S-C torsion angle of -61.3 (2). ...
The title compound, C23H22N2O2S, crystallizes with the 4-methyl-benzene-sulfonamide entity oriented towards the center of the bridgeh …
N-(2,6-Dimeth-oxy-pyridin-3-yl)-9-methyl-9H-carbazole-3-sulfonamide.
Shan G, Li Z, Hu L, Jiang J, Liu Z. Shan G, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 23;69(Pt 4):o584. doi: 10.1107/S1600536813007460. Print 2013 Apr 1. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23634116 Free PMC article.
Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation.
Wan Y, Fang G, Chen H, Deng X, Tang Z. Wan Y, et al. Eur J Med Chem. 2021 Dec 15;226:113837. doi: 10.1016/j.ejmech.2021.113837. Epub 2021 Sep 8. Eur J Med Chem. 2021. PMID: 34530384 Review.
In this review, we summed up the recent advances of sulfonamide derivatives as potential anti-cancer agents based on the anti-cancer targets, such as aromatase, carbonic anhydrase (CA), anti-apoptotic B-cell lymphoma-2 (Bcl-2) proteins, topoisomerase and phosphatidylinosit …
In this review, we summed up the recent advances of sulfonamide derivatives as potential anti-cancer agents based on the anti-cancer …
Heteroaryl sulfonamide synthesis: scope and limitations.
Iakovenko RO, Chrenko D, Kristek J, Desmedt E, Zálešák F, De Vleeschouwer F, Pospíšil J. Iakovenko RO, et al. Org Biomol Chem. 2022 Apr 13;20(15):3154-3159. doi: 10.1039/d2ob00345g. Org Biomol Chem. 2022. PMID: 35343994
Heteroaryl sulfonamides are important structural motifs in the medicinal and agrochemical industries. However, their synthesis often relies on the use of heteroaryl sulfonyl chlorides, which are unstable and toxic reagents. ...
Heteroaryl sulfonamides are important structural motifs in the medicinal and agrochemical industries. However, their synthesis often …
Sulfonamide drugs: structure, antibacterial property, toxicity, and biophysical interactions.
Ovung A, Bhattacharyya J. Ovung A, et al. Biophys Rev. 2021 Mar 29;13(2):259-272. doi: 10.1007/s12551-021-00795-9. eCollection 2021 Apr. Biophys Rev. 2021. PMID: 33936318 Free PMC article. Review.
Sulfonamide (or sulphonamide) functional group chemistry (SN) forms the basis of several groups of drug. ...Sulfamethazine (SMZ) is a commonly used sulphonamide drug in veterinary medicine that acts as an antibacterial compound to treat livestock diseases such as ga
Sulfonamide (or sulphonamide) functional group chemistry (SN) forms the basis of several groups of drug. ...Sulfamethazine (SMZ) is a
Sulfonamide derivatives as multi-target agents for complex diseases.
Apaydın S, Török M. Apaydın S, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2042-2050. doi: 10.1016/j.bmcl.2019.06.041. Epub 2019 Jun 25. Bioorg Med Chem Lett. 2019. PMID: 31272793 Review.
Sulfonamide derivatives are frequently seen structural motifs in medicinal chemistry. ...This digest aims to provide an overview of recent advances in sulfonamide-based bioactive compounds, their importance in drug discovery and development emphasizing multi-
Sulfonamide derivatives are frequently seen structural motifs in medicinal chemistry. ...This digest aims to provide an overvi
Synthesis of sulfonopeptides.
Xu J. Xu J. J Pept Sci. 2021 Aug;27(8):e3331. doi: 10.1002/psc.3331. Epub 2021 Apr 28. J Pept Sci. 2021. PMID: 33913204 Review.
Sulfonopeptides as the sulfur analogues of natural peptides have been widely used as enzyme inhibitors due to their tetrahedral sulfonamide moiety, which can mimic the transition-state analogues of hydrolysis of the ester and amide bonds. ...The developed synthetic methods …
Sulfonopeptides as the sulfur analogues of natural peptides have been widely used as enzyme inhibitors due to their tetrahedral sulfonami
The anticancer therapeutic potential of pyrimidine-sulfonamide hybrids.
Zhang P, Shi C, Dong T, Song J, Du G. Zhang P, et al. Future Med Chem. 2024 Apr 16. doi: 10.4155/fmc-2024-0010. Online ahead of print. Future Med Chem. 2024. PMID: 38624011 Review.
Pyrimidines, including fused pyrimidines, are privileged scaffolds for various biological cancer targets and are the most important class of metalloenzyme carbonic anhydrase inhibitors. Pyrimidine-sulfonamide hybrids can act on different targets in cancer cells simultaneou …
Pyrimidines, including fused pyrimidines, are privileged scaffolds for various biological cancer targets and are the most important class of …
2,188 results