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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
1947 1
1948 1
1949 1
1950 8
1951 6
1952 3
1953 1
1954 4
1956 2
1957 1
1959 1
1961 1
1962 2
1963 16
1964 13
1965 12
1966 7
1967 14
1968 14
1969 9
1970 6
1971 6
1972 6
1973 4
1974 8
1975 4
1976 10
1977 8
1978 5
1979 5
1980 9
1981 5
1982 1
1983 5
1984 4
1985 10
1986 8
1987 10
1988 5
1989 3
1990 9
1991 3
1992 4
1993 4
1994 3
1995 3
1996 5
1997 7
1998 2
1999 4
2000 4
2001 6
2002 2
2003 8
2004 14
2005 19
2006 26
2007 25
2008 12
2009 14
2010 16
2011 24
2012 12
2013 19
2014 12
2015 7
2016 17
2017 28
2018 30
2019 22
2020 18
2021 26
2022 19
2023 23
2024 9

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644 results

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Page 1
Synephrine and Its Derivative Compound A: Common and Specific Biological Effects.
Dodonova SA, Zhidkova EM, Kryukov AA, Valiev TT, Kirsanov KI, Kulikov EP, Budunova IV, Yakubovskaya MG, Lesovaya EA. Dodonova SA, et al. Int J Mol Sci. 2023 Dec 15;24(24):17537. doi: 10.3390/ijms242417537. Int J Mol Sci. 2023. PMID: 38139366 Free PMC article. Review.
Additionally, we conduct a comparative analysis of the molecular targets and effects of synephrine with those of its metabolite, selective glucocorticoid receptor agonist (SEGRA) Compound A (CpdA), which shares a similar chemical structure with synephrine. ...The re …
Additionally, we conduct a comparative analysis of the molecular targets and effects of synephrine with those of its metabolite, sele …
Effects of p-Synephrine during Exercise: A Brief Narrative Review.
Ruiz-Moreno C, Del Coso J, Giráldez-Costas V, González-García J, Gutiérrez-Hellín J. Ruiz-Moreno C, et al. Nutrients. 2021 Jan 15;13(1):233. doi: 10.3390/nu13010233. Nutrients. 2021. PMID: 33467423 Free PMC article. Review.
The p-synephrine is the principal phytochemical found in bitter orange (Citrus aurantium). ...However, the effects of p-synephrine on fat oxidation during exercise have been investigated in the last few years. ...
The p-synephrine is the principal phytochemical found in bitter orange (Citrus aurantium). ...However, the effects of p-synephrine …
p-Synephrine, ephedrine, p-octopamine and m-synephrine: Comparative mechanistic, physiological and pharmacological properties.
Stohs SJ, Shara M, Ray SD. Stohs SJ, et al. Phytother Res. 2020 Aug;34(8):1838-1846. doi: 10.1002/ptr.6649. Epub 2020 Feb 26. Phytother Res. 2020. PMID: 32101364 Free PMC article. Review.
Confusion and misunderstanding exist regarding the lack of cardiovascular and other adverse health effects of p-synephrine and p-octopamine relative to ephedrine and m-synephrine (phenylephrine) which are known for their effects on the cardiovascular system. ...The …
Confusion and misunderstanding exist regarding the lack of cardiovascular and other adverse health effects of p-synephrine and p-octo …
[Synephrine in dietary supplements and specialized foodstuffs: biological activity, safety and methods of analysis].
Perova IB, Eller KI, Musatov AV, Tymolskaya EV. Perova IB, et al. Vopr Pitan. 2021;90(6):101-113. doi: 10.33029/0042-8833-2021-90-6-101-113. Epub 2021 Oct 26. Vopr Pitan. 2021. PMID: 35032130 Review. Russian.
Because of insufficient safety data, the consumption of synephrine is regulated in the Russian Federation and abroad. The upper permissible level of synephrine consumption in the Russian Federation is 30 mg per day. Various cases of adulteration of DS and SF for wei …
Because of insufficient safety data, the consumption of synephrine is regulated in the Russian Federation and abroad. The upper permi …
Synephrine: from trace concentrations to massive consumption in weight-loss.
Rossato LG, Costa VM, Limberger RP, Bastos Mde L, Remião F. Rossato LG, et al. Food Chem Toxicol. 2011 Jan;49(1):8-16. doi: 10.1016/j.fct.2010.11.007. Epub 2010 Nov 12. Food Chem Toxicol. 2011. PMID: 21075161 Review.
Synephrine exists in three different positional isomers; however, only p- and m-synephrine have been described in weight-loss products. The alleged effectiveness of synephrine-containing supplements is attributed to the thermogenic effects arising from syn …
Synephrine exists in three different positional isomers; however, only p- and m-synephrine have been described in weight-loss …
[Risk assessment of synephrine in dietary supplements].
Bakhyia N, Dusemund B, Richter K, Lindtner O, Hirsch-Ernst KI, Schäfer B, Lampen A. Bakhyia N, et al. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017 Mar;60(3):323-331. doi: 10.1007/s00103-016-2506-5. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017. PMID: 28058460 Review. German.
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. ...Some human intervention studies investigating the acute effects of synephrine on blood pressure and heart rate of healthy, normotensive test persons indicate that …
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. ...Some human intervention studie …
A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects.
Stohs SJ, Preuss HG, Shara M. Stohs SJ, et al. Oxid Med Cell Longev. 2011;2011:482973. doi: 10.1155/2011/482973. Epub 2011 Aug 1. Oxid Med Cell Longev. 2011. PMID: 21904645 Free PMC article. Review.
Because of structural similarities, the pharmacological effects of p-synephrine are widely assumed to be similar to those of ephedrine, m-synephrine (phenylephrine), and endogenous amine neurotransmitters as norepinephrine and epinephrine. ...This paper summarizes t …
Because of structural similarities, the pharmacological effects of p-synephrine are widely assumed to be similar to those of ephedrin …
Review of Published Bitter Orange Extract and p-Synephrine Adverse Event Clinical Study Case Reports.
Stohs SJ, Ray SD. Stohs SJ, et al. J Diet Suppl. 2020;17(3):355-363. doi: 10.1080/19390211.2019.1577936. Epub 2019 Mar 5. J Diet Suppl. 2020. PMID: 30835576 Review.
p-Synephrine is the primary active ingredient in bitter orange (Citrus aurantium) extract and is present in other citrus species. ...In no case was a direct correlation between the event and p-synephrine made. Although p-synephrine and ephedrine have some str …
p-Synephrine is the primary active ingredient in bitter orange (Citrus aurantium) extract and is present in other citrus species. ... …
Safety, Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p-Synephrine.
Stohs SJ. Stohs SJ. Phytother Res. 2017 Oct;31(10):1463-1474. doi: 10.1002/ptr.5879. Epub 2017 Jul 28. Phytother Res. 2017. PMID: 28752649 Free PMC article. Review.
Questions have been raised about the safety of p-synephrine because it has some structural similarity to ephedrine. This review focuses on current human, animal, in vitro, and mechanistic studies that address the safety, efficacy, and mechanisms of action of bitter orange …
Questions have been raised about the safety of p-synephrine because it has some structural similarity to ephedrine. This review focus …
Review of Case Reports on Adverse Events Related to Pre-workout Supplements Containing Synephrine.
de Jonge MLL, Kieviet LC, Sierts M, Egberink LB, van der Heyden MAG. de Jonge MLL, et al. Cardiovasc Toxicol. 2023 Jan;23(1):1-9. doi: 10.1007/s12012-022-09777-z. Epub 2023 Jan 13. Cardiovasc Toxicol. 2023. PMID: 36639595 Free PMC article. Review.
The use of pre-workout supplements has become increasingly popular, including the use of supplements containing synephrine. Synephrine might stimulate weight loss and improve sports performance by its proposed adrenergic properties. However, with its increasing popu …
The use of pre-workout supplements has become increasingly popular, including the use of supplements containing synephrine. Syneph …
644 results