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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1965 1
1966 1
1967 6
1968 10
1969 5
1970 7
1971 7
1972 7
1973 19
1974 17
1975 22
1976 13
1977 19
1978 13
1979 24
1980 10
1981 17
1982 23
1983 19
1984 26
1985 29
1986 26
1987 30
1988 23
1989 27
1990 30
1991 22
1992 28
1993 47
1994 40
1995 41
1996 33
1997 60
1998 45
1999 45
2000 47
2001 75
2002 51
2003 71
2004 69
2005 91
2006 96
2007 96
2008 101
2009 90
2010 97
2011 145
2012 141
2013 135
2014 136
2015 114
2016 137
2017 148
2018 143
2019 153
2020 134
2021 134
2022 109
2023 95
2024 26

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3,025 results

Results by year

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Page 1
Methotrexate to treat hand osteoarthritis with synovitis (METHODS): an Australian, multisite, parallel-group, double-blind, randomised, placebo-controlled trial.
Wang Y, Jones G, Keen HI, Hill CL, Wluka AE, Kasza J, Teichtahl AJ, Antony B, O'Sullivan R, Cicuttini FM. Wang Y, et al. Lancet. 2023 Nov 11;402(10414):1764-1772. doi: 10.1016/S0140-6736(23)01572-6. Epub 2023 Oct 12. Lancet. 2023. PMID: 37839420 Clinical Trial.
We aimed to examine the efficacy and safety of methotrexate at 6 months in participants with hand osteoarthritis and synovitis. METHODS: In this multisite, parallel-group, double-blind, randomised, placebo-controlled trial, participants (aged 40-75 years) wit …
We aimed to examine the efficacy and safety of methotrexate at 6 months in participants with hand osteoarthritis and synovitis. METHO …
Faecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice.
Huang Z, Chen J, Li B, Zeng B, Chou CH, Zheng X, Xie J, Li H, Hao Y, Chen G, Pei F, Shen B, Kraus VB, Wei H, Zhou X, Cheng L. Huang Z, et al. Ann Rheum Dis. 2020 May;79(5):646-656. doi: 10.1136/annrheumdis-2019-216471. Epub 2020 Mar 23. Ann Rheum Dis. 2020. PMID: 32205337 Free PMC article.
Eight weeks after MLI, mice were evaluated for histological OA severity and synovitis, systemic inflammation and gut permeability. RESULTS: Histological OA severity following MLI was minimal in germ-free mice. ...
Eight weeks after MLI, mice were evaluated for histological OA severity and synovitis, systemic inflammation and gut permeability. RE …
Response to secukinumab on synovitis using Power Doppler ultrasound in psoriatic arthritis: 12-week results from a phase III study, ULTIMATE.
D'Agostino MA, Schett G, López-Rdz A, Šenolt L, Fazekas K, Burgos-Vargas R, Maldonado-Cocco J, Naredo E, Carron P, Duggan AM, Goyanka P, Boers M, Gaillez C. D'Agostino MA, et al. Rheumatology (Oxford). 2022 May 5;61(5):1867-1876. doi: 10.1093/rheumatology/keab628. Rheumatology (Oxford). 2022. PMID: 34528079 Free PMC article. Clinical Trial.
METHODS: The randomized, placebo-controlled, Phase III ULTIMATE study enrolled PsA patients with active ultrasound synovitis and clinical synovitis and enthesitis having an inadequate response to conventional DMARDs and naive to biologic DMARDs. ...CON …
METHODS: The randomized, placebo-controlled, Phase III ULTIMATE study enrolled PsA patients with active ultrasound synovitis a …
Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial.
McAlindon TE, LaValley MP, Harvey WF, Price LL, Driban JB, Zhang M, Ward RJ. McAlindon TE, et al. JAMA. 2017 May 16;317(19):1967-1975. doi: 10.1001/jama.2017.5283. JAMA. 2017. PMID: 28510679 Free PMC article. Clinical Trial.
IMPORTANCE: Synovitis is common and is associated with progression of structural characteristics of knee osteoarthritis. ...OBJECTIVE: To determine the effects of intra-articular injection of 40 mg of triamcinolone acetonide every 3 months on progression of cartilage loss …
IMPORTANCE: Synovitis is common and is associated with progression of structural characteristics of knee osteoarthritis. ...OBJECTIVE …
Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study.
Kampylafka E, Simon D, d'Oliveira I, Linz C, Lerchen V, Englbrecht M, Rech J, Kleyer A, Sticherling M, Schett G, Hueber AJ. Kampylafka E, et al. Arthritis Res Ther. 2019 Jul 26;21(1):178. doi: 10.1186/s13075-019-1957-0. Arthritis Res Ther. 2019. PMID: 31349876 Free PMC article. Clinical Trial.
Total PsAMRIS (p = 0.005) and synovitis subscore (p = 0.008) also significantly improved. Erosions and enthesiophytes did not progress, while bone mass in the distal radius significantly (p = 0.020) increased after 24 weeks. ...IVEPSA therefore provides rationale for futur …
Total PsAMRIS (p = 0.005) and synovitis subscore (p = 0.008) also significantly improved. Erosions and enthesiophytes did not progres …
Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion-Synovitis of Knee Osteoarthritis : A Randomized Trial.
Wang Z, Jones G, Winzenberg T, Cai G, Laslett LL, Aitken D, Hopper I, Singh A, Jones R, Fripp J, Ding C, Antony B. Wang Z, et al. Ann Intern Med. 2020 Dec 1;173(11):861-869. doi: 10.7326/M20-0990. Epub 2020 Sep 15. Ann Intern Med. 2020. PMID: 32926799 Clinical Trial.
DESIGN: Randomized, double-blind, placebo-controlled trial. (Australian New Zealand Clinical Trials Registry: ACTRN12618000080224). ...CONCLUSION: CL was more effective than placebo for knee pain but did not affect knee effusion-synovitis or cartilage …
DESIGN: Randomized, double-blind, placebo-controlled trial. (Australian New Zealand Clinical Trials Registry: ACTRN1261 …
Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation.
Chahal J, Gómez-Aristizábal A, Shestopaloff K, Bhatt S, Chaboureau A, Fazio A, Chisholm J, Weston A, Chiovitti J, Keating A, Kapoor M, Ogilvie-Harris DJ, Syed KA, Gandhi R, Mahomed NN, Marshall KW, Sussman MS, Naraghi AM, Viswanathan S. Chahal J, et al. Stem Cells Transl Med. 2019 Aug;8(8):746-757. doi: 10.1002/sctm.18-0183. Epub 2019 Apr 9. Stem Cells Transl Med. 2019. PMID: 30964245 Free PMC article. Clinical Trial.
Patients with late-stage Kellgren-Lawrence knee osteoarthritis received a single intra-articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) in a phase I/IIa trial to assess safety and efficacy using a broad toolset of analytical metho …
Patients with late-stage Kellgren-Lawrence knee osteoarthritis received a single intra-articular injection of 1, 10, or 50 million bone marr …
Anti-IL17 treatment in childhood chronic rheumatic diseases.
Maniscalco V, Maccora I, Girodo F, Tomaselli M, Priolo G, Marrani E, Mastrolia MV, Pagnini I, Simonini G. Maniscalco V, et al. Expert Opin Biol Ther. 2023 May;23(5):429-441. doi: 10.1080/14712598.2023.2215923. Epub 2023 May 19. Expert Opin Biol Ther. 2023. PMID: 37195125 Review.
To date, the available evidence is limited and mainly focuses on juvenile idiopathic arthritis (JIA) and a specific autoinflammatory disease called deficiency of IL-36 receptor antagonist (DITRA). Recently, a randomized controlled trial resulted in the approval of s …
To date, the available evidence is limited and mainly focuses on juvenile idiopathic arthritis (JIA) and a specific autoinflammatory disease …
Baricitinib Improves Bone Properties and Biomechanics in Patients With Rheumatoid Arthritis: Results of the Prospective Interventional BARE BONE Trial.
Simon D, Minopoulou I, Kemenes S, Bayat S, Tascilar K, Mutlu MY, Valor-Méndez L, Krönke G, Hueber AJ, Schett G, Kleyer A. Simon D, et al. Arthritis Rheumatol. 2023 Nov;75(11):1923-1934. doi: 10.1002/art.42617. Epub 2023 Sep 21. Arthritis Rheumatol. 2023. PMID: 37229650 Clinical Trial.
METHODS: Prospective, single-arm, interventional, open-label, single-center phase 4 study in RA patients with pathological bone status and clinical indication of JAKi (BARE BONE trial). Participants received BARI (4 mg/day) over 52 weeks. To assess bone properties a …
METHODS: Prospective, single-arm, interventional, open-label, single-center phase 4 study in RA patients with pathological bone status and …
Effects of secukinumab on synovitis and enthesitis in patients with psoriatic arthritis: 52-week clinical and ultrasound results from the randomised, double-blind ULTIMATE trial with open label extension.
D'Agostino MA, Carron P, Gaillez C, Conaghan PG, Naredo E, López-Rdz A, Šenolt L, Burgos-Vargas R, Hanova P, Padovano I, Cazenave T, Stoenoiu MS, Backhaus M, Mouterde G, Bao W, Goyanka P, Boers M, Schett G. D'Agostino MA, et al. Semin Arthritis Rheum. 2023 Dec;63:152259. doi: 10.1016/j.semarthrit.2023.152259. Epub 2023 Aug 19. Semin Arthritis Rheum. 2023. PMID: 37660536 Free article. Clinical Trial.
METHODS: This randomised, placebo-controlled, Phase 3 study (ULTIMATE) included biologic-naive patients with PsA with active PDUS synovitis and clinical enthesitis, and inadequate response to conventional synthetic disease-modifying antirheumatic drugs. ...Th …
METHODS: This randomised, placebo-controlled, Phase 3 study (ULTIMATE) included biologic-naive patients with PsA with active PDUS …
3,025 results