Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 2
2003 1
2004 1
2005 1
2006 3
2007 2
2008 5
2009 2
2010 4
2011 7
2012 6
2013 7
2014 10
2015 9
2016 11
2017 22
2018 17
2019 14
2020 17
2021 25
2022 19
2023 19
2024 7

Text availability

Article attribute

Article type

Publication date

Search Results

184 results

Results by year

Filters applied: . Clear all
Page 1
Stages in the development of Parkinson's disease-related pathology.
Braak H, Ghebremedhin E, Rüb U, Bratzke H, Del Tredici K. Braak H, et al. Cell Tissue Res. 2004 Oct;318(1):121-34. doi: 10.1007/s00441-004-0956-9. Epub 2004 Aug 24. Cell Tissue Res. 2004. PMID: 15338272 Review.
The intracerebral formation of abnormal proteinaceous Lewy bodies and Lewy neurites begins at defined induction sites and advances in a topographically predictable sequence. As the disease progresses, components of the autonomic, limbic, and somatomotor systems become part …
The intracerebral formation of abnormal proteinaceous Lewy bodies and Lewy neurites begins at defined induction sites and advances in a topo …
Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder.
Miglis MG, Adler CH, Antelmi E, Arnaldi D, Baldelli L, Boeve BF, Cesari M, Dall'Antonia I, Diederich NJ, Doppler K, Dušek P, Ferri R, Gagnon JF, Gan-Or Z, Hermann W, Högl B, Hu MT, Iranzo A, Janzen A, Kuzkina A, Lee JY, Leenders KL, Lewis SJG, Liguori C, Liu J, Lo C, Ehgoetz Martens KA, Nepozitek J, Plazzi G, Provini F, Puligheddu M, Rolinski M, Rusz J, Stefani A, Summers RLS, Yoo D, Zitser J, Oertel WH. Miglis MG, et al. Lancet Neurol. 2021 Aug;20(8):671-684. doi: 10.1016/S1474-4422(21)00176-9. Lancet Neurol. 2021. PMID: 34302789 Free PMC article. Review.
These findings provide the rationale to develop reliable biomarkers that can better predict conversion to clinically manifest alpha-synucleinopathies. In addition, biomarkers of disease progression will be essential to monitor treatment response once disease-modifying ther …
These findings provide the rationale to develop reliable biomarkers that can better predict conversion to clinically manifest alpha-s …
Alpha-synucleinopathies.
Alafuzoff I, Hartikainen P. Alafuzoff I, et al. Handb Clin Neurol. 2017;145:339-353. doi: 10.1016/B978-0-12-802395-2.00024-9. Handb Clin Neurol. 2017. PMID: 28987181 Review.
Furthermore, since the 1990s it has been acknowledged that progressions of most neurodegenerative pathologies follow a certain predictable time-related neuroanatomic distribution. Currently, for Lewy body disease, two staging techniques are commonly used: McKeith and Braak …
Furthermore, since the 1990s it has been acknowledged that progressions of most neurodegenerative pathologies follow a certain predictabl …
α-Synucleinopathy phenotypes.
McCann H, Stevens CH, Cartwright H, Halliday GM. McCann H, et al. Parkinsonism Relat Disord. 2014 Jan;20 Suppl 1:S62-7. doi: 10.1016/S1353-8020(13)70017-8. Parkinsonism Relat Disord. 2014. PMID: 24262191 Review.
Identifying the factors involved in causing different alpha-synuclein phenotypes may ultimately lead to more targeted therapeutics as well as more accurate clinical prognosis....
Identifying the factors involved in causing different alpha-synuclein phenotypes may ultimately lead to more targeted therapeutics as well a …
Pure Autonomic Failure.
Thaisetthawatkul P. Thaisetthawatkul P. Curr Neurol Neurosci Rep. 2016 Aug;16(8):74. doi: 10.1007/s11910-016-0673-2. Curr Neurol Neurosci Rep. 2016. PMID: 27338613 Review.
Management of autonomic symptoms is the mainstay of treatment and includes management of orthostatic hypotension and supine hypertension. The prognosis for survival of PAF is better than for the other synucleinopathies....
Management of autonomic symptoms is the mainstay of treatment and includes management of orthostatic hypotension and supine hypertension. Th …
Progression of clinical markers in prodromal Parkinson's disease and dementia with Lewy bodies: a multicentre study.
Joza S, Hu MT, Jung KY, Kunz D, Stefani A, Dušek P, Terzaghi M, Arnaldi D, Videnovic A, Schiess MC, Hermann W, Lee JY, Ferini-Strambi L, Lewis SJG, Leclair-Visonneau L, Oertel WH, Antelmi E, Sixel-Döring F, Cochen De Cock V, Liguori C, Liu J, Provini F, Puligheddu M, Nicoletti A, Bassetti CLA, Bušková J, Dauvilliers Y, Ferri R, Montplaisir JY, Lawton M, Kim HJ, Bes F, Högl B, Šonka K, Fiamingo G, Mattioli P, Lavadia ML, Suescun J, Woo KA, Marelli S, Martens KE, Janzen A, Plazzi G, Mollenhauer B, Fernandes M, Li Y, Cortelli P, Figorilli M, Cicero CE, Schaefer C, Guiraud L, Lanza G, Gagnon JF, Sunwoo JS, Ibrahim A, Girtler N, Trenkwalder C, Baldelli L, Pelletier A, Postuma RB; International REM Sleep Behavior Disorder Study Group. Joza S, et al. Brain. 2023 Aug 1;146(8):3258-3272. doi: 10.1093/brain/awad072. Brain. 2023. PMID: 36881989 Free article.
Among these, idiopathic REM sleep behaviour disorder is a powerful early predictor of eventual phenoconversion, and therefore represents a critical opportunity to intervene with neuroprotective therapy. ...
Among these, idiopathic REM sleep behaviour disorder is a powerful early predictor of eventual phenoconversion, and therefore represe …
Sympathetic neuroimaging.
Goldstein DS. Goldstein DS. Handb Clin Neurol. 2013;117:365-70. doi: 10.1016/B978-0-444-53491-0.00029-8. Handb Clin Neurol. 2013. PMID: 24095139 Free PMC article. Review.
Based on heart:mediastinum ratios of (123)I-MIBG-derived radioactivity, decreased uptake, increased washout, or both have been reported in many disorders and relate to diagnosis and prognosis. Cardiac sympathetic neuroimaging and postmortem neuropathological findings have …
Based on heart:mediastinum ratios of (123)I-MIBG-derived radioactivity, decreased uptake, increased washout, or both have been reported in m …
Baseline characteristics of the North American prodromal Synucleinopathy cohort.
Elliott JE, Lim MM, Keil AT, Postuma RB, Pelletier A, Gagnon JF, St Louis EK, Forsberg LK, Fields JA, Huddleston DE, Bliwise DL, Avidan AY, Howell MJ, Schenck CH, McLeland J, Criswell SR, Videnovic A, During EH, Miglis MG, Shprecher DR, Lee-Iannotti JK, Boeve BF, Ju YS; North American Prodromal Synucleinopathy (NAPS) Consortium. Elliott JE, et al. Ann Clin Transl Neurol. 2023 Apr;10(4):520-535. doi: 10.1002/acn3.51738. Epub 2023 Feb 8. Ann Clin Transl Neurol. 2023. PMID: 36751940 Free PMC article. Clinical Trial.
The North American Prodromal Synucleinopathy (NAPS) Consortium has created a multisite RBD participant, primarily clinic-based cohort to better understand characteristics at diagnosis, and in future work, identify predictors of phenoconversion, develop synucleinopathy biom …
The North American Prodromal Synucleinopathy (NAPS) Consortium has created a multisite RBD participant, primarily clinic-based cohort to bet …
Ethical Aspects of Prodromal Synucleinopathy Prognostic Counseling.
Stefani A, Mozersky J, Kotagal V, Högl B, Ingravallo F, Ju YS, Avidan A, Sharp R, Videnovic A, Schenck CH, St Louis EK. Stefani A, et al. Semin Neurol. 2023 Feb;43(1):166-177. doi: 10.1055/a-2019-0245. Epub 2023 Jan 24. Semin Neurol. 2023. PMID: 36693433 Review.
Asking about willingness to know in clinical and research settings and the shared decision-making process applied to prognostic counseling is discussed. Concerning research settings, ethical aspects regarding clinical trials are addressed. Availability of direct-to-consume …
Asking about willingness to know in clinical and research settings and the shared decision-making process applied to prognostic couns …
The genetic basis of multiple system atrophy.
Tseng FS, Foo JQX, Mai AS, Tan EK. Tseng FS, et al. J Transl Med. 2023 Feb 10;21(1):104. doi: 10.1186/s12967-023-03905-1. J Transl Med. 2023. PMID: 36765380 Free PMC article. Review.
Furthermore, we highlight various genetic polymorphisms that modulate MSA risk, including complex gene-gene and gene-environment interactions, which influence the disease phenotype and have clinical significance in both presentation and prognosis. Deciphering the exact mec …
Furthermore, we highlight various genetic polymorphisms that modulate MSA risk, including complex gene-gene and gene-environment interaction …
184 results