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Quoted phrase not found in phrase index: "Systemic lupus erythematosus, susceptibility to, 8"
Page 1
Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.
Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Laurynenka V, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang Y, Amano K, Park DJ, Yang W, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y; Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head; Kottyan LC, Weirauch MT, Parameswaran S, Eswar S, Salim H, Chen X, Yamamoto K, Harley JB, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC. Yin X, et al. Ann Rheum Dis. 2021 May;80(5):632-640. doi: 10.1136/annrheumdis-2020-219209. Epub 2020 Dec 3. Ann Rheum Dis. 2021. PMID: 33272962 Free PMC article.
OBJECTIVE: Systemic lupus erythematosus (SLE), an autoimmune disorder, has been associated with nearly 100 susceptibility loci. ...We identified 110 putative causal variants with posterior probabilities 0.1 for 57 SLE loci, among which we prioritised 1 …
OBJECTIVE: Systemic lupus erythematosus (SLE), an autoimmune disorder, has been associated with nearly 100 susceptib …
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease.
Saevarsdottir S, Olafsdottir TA, Ivarsdottir EV, Halldorsson GH, Gunnarsdottir K, Sigurdsson A, Johannesson A, Sigurdsson JK, Juliusdottir T, Lund SH, Arnthorsson AO, Styrmisdottir EL, Gudmundsson J, Grondal GM, Steinsson K, Alfredsson L, Askling J, Benediktsson R, Bjarnason R, Geirsson AJ, Gudbjornsson B, Gudjonsson H, Hjaltason H, Hreidarsson AB, Klareskog L, Kockum I, Kristjansdottir H, Love TJ, Ludviksson BR, Olsson T, Onundarson PT, Orvar KB, Padyukov L, Sigurgeirsson B, Tragante V, Bjarnadottir K, Rafnar T, Masson G, Sulem P, Gudbjartsson DF, Melsted P, Thorleifsson G, Norddahl GL, Thorsteinsdottir U, Jonsdottir I, Stefansson K. Saevarsdottir S, et al. Nature. 2020 Aug;584(7822):619-623. doi: 10.1038/s41586-020-2436-0. Epub 2020 Jun 24. Nature. 2020. PMID: 32581359
Autoimmune thyroid disease is the most common autoimmune disease and is highly heritable(1). ...A low-frequency (1.36%) intronic variant in FLT3 (rs76428106-C) has the largest effect on risk of autoimmune thyroid disease (odds ratio (OR) = 1.46, P = 2.37 10(- …
Autoimmune thyroid disease is the most common autoimmune disease and is highly heritable(1). ...A low-frequency (1.36%) intron …
Genetic variation and systemic lupus erythematosus: A field synopsis and systematic meta-analysis.
Jeong DY, Lee SW, Park YH, Choi JH, Kwon YW, Moon G, Eisenhut M, Kronbichler A, Shin JI. Jeong DY, et al. Autoimmun Rev. 2018 Jun;17(6):553-566. doi: 10.1016/j.autrev.2017.12.011. Epub 2018 Apr 7. Autoimmun Rev. 2018. PMID: 29635078 Review.
Systemic lupus erythematosus (SLE) is a multi-systemic severe autoimmune disease which results from the irreversible loss of self-tolerance and impaired molecular responses, especially an altered interferon signature. ...When determining results …
Systemic lupus erythematosus (SLE) is a multi-systemic severe autoimmune disease which results from the i …
Schizophrenia Genetics and Neuropsychiatric Features in Childhood-onset Systemic Lupus Erythematosus.
Ulloa AC, Liao F, Carlomagno RL, Diaz T, Dominguez D, Levy DM, Ng L, Knight AM, Hiraki LT. Ulloa AC, et al. J Rheumatol. 2022 Feb;49(2):192-196. doi: 10.3899/jrheum.210363. Epub 2021 Oct 1. J Rheumatol. 2022. PMID: 34599046
OBJECTIVE: We examined the association between schizophrenia genetic susceptibility loci and neuropsychiatric systemic lupus erythematosus (NPSLE) features in childhood-onset SLE (cSLE) participants. ...We calculated 2 additive schizophrenia-weighted p …
OBJECTIVE: We examined the association between schizophrenia genetic susceptibility loci and neuropsychiatric systemic lupu …
Aicardi-Goutières syndrome (AGS).
Stephenson JB. Stephenson JB. Eur J Paediatr Neurol. 2008 Sep;12(5):355-8. doi: 10.1016/j.ejpn.2007.11.010. Epub 2008 Mar 14. Eur J Paediatr Neurol. 2008. PMID: 18343173 Review.
The increased interferon-alpha in affected children (Pierre Lebon, Paris) mimicked congenital viral infection, but the associated chilblains (pernio) pointed to lupus erythematosus and an autoimmune mechanism. Genetic research led by Yanick Crow has clarified these …
The increased interferon-alpha in affected children (Pierre Lebon, Paris) mimicked congenital viral infection, but the associated chilblains …
The genetics of systemic lupus erythematosus and implications for targeted therapy.
Sestak AL, Fürnrohr BG, Harley JB, Merrill JT, Namjou B. Sestak AL, et al. Ann Rheum Dis. 2011 Mar;70 Suppl 1:i37-43. doi: 10.1136/ard.2010.138057. Ann Rheum Dis. 2011. PMID: 21339217 Review.
Observations of familial aggregation (lambdas=8-29) and a 40% identical twin concordance rate prompted recent work towards a comprehensive genetic analysis of systemic lupus erythematosus (SLE). ...Approximately 35 genes associated with lupus …
Observations of familial aggregation (lambdas=8-29) and a 40% identical twin concordance rate prompted recent work towards a c …
Association between BLK polymorphisms and susceptibility to SLE : A meta-analysis.
Song GG, Lee YH. Song GG, et al. Z Rheumatol. 2017 Mar;76(2):176-182. doi: 10.1007/s00393-016-0072-8. Z Rheumatol. 2017. PMID: 27067206 Review. English.
OBJECTIVE: This study aimed to explore whether B-cell lymphocyte kinase (BLK) polymorphisms are associated with susceptibility to systemic lupus erythematosus (SLE) in ethnically diverse populations. ...A significant association between SLE and the rs2 …
OBJECTIVE: This study aimed to explore whether B-cell lymphocyte kinase (BLK) polymorphisms are associated with susceptibility to …
Familial Aggregation of Childhood- and Adulthood-Onset Systemic Lupus Erythematosus.
Sinicato NA, de Oliveira L, Lapa A, Postal M, Peliçari KO, Costallat LTL, Marini R, Gil-da-Silva-Lopes VL, Niewold TB, Appenzeller S. Sinicato NA, et al. Arthritis Care Res (Hoboken). 2020 Aug;72(8):1147-1151. doi: 10.1002/acr.23931. Epub 2020 Jun 11. Arthritis Care Res (Hoboken). 2020. PMID: 31127864
OBJECTIVE: To assess the familial occurrence of systemic lupus erythematosus (SLE) in a large Brazilian cohort. METHODS: Consecutive patients with SLE were recruited and stratified according to age at disease onset into childhood-onset SLE or adult-ons …
OBJECTIVE: To assess the familial occurrence of systemic lupus erythematosus (SLE) in a large Brazilian cohort. METHODS …
Systemic Lupus Erythematosus: Targeted Literature Review of the Epidemiology, Current Treatment, and Disease Burden in the Asia Pacific Region.
Tanaka Y, O'Neill S, Li M, Tsai IC, Yang YW. Tanaka Y, et al. Arthritis Care Res (Hoboken). 2022 Feb;74(2):187-198. doi: 10.1002/acr.24431. Epub 2022 Jan 10. Arthritis Care Res (Hoboken). 2022. PMID: 32841537 Review.
OBJECTIVE: To understand the epidemiology, current treatment, and disease burden of systemic lupus erythematosus (SLE) in the Asia Pacific (APAC) region. ...Asian patients with SLE were reported to have higher disease severity, disease ac …
OBJECTIVE: To understand the epidemiology, current treatment, and disease burden of systemic lupus erythematosus …
Systemic lupus erythematosus and toll-like receptor 9 polymorphisms: A meta-analysis of genetic association studies.
Lee YH, Song GG. Lee YH, et al. Lupus. 2023 Jul;32(8):964-973. doi: 10.1177/09612033231180695. Epub 2023 Jun 2. Lupus. 2023. PMID: 37265090
OBJECTIVE: This study aimed to examine whether polymorphisms in toll-like receptor 9 (TLR9) contribute to vulnerability to systemic lupus erythematosus (SLE). METHODS: We searched the MEDLINE, Embase, and Web of Science databases for relevant articles. ...TLR …
OBJECTIVE: This study aimed to examine whether polymorphisms in toll-like receptor 9 (TLR9) contribute to vulnerability to systemic …
243 results