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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2009 4
2010 9
2011 9
2012 11
2013 11
2014 13
2015 17
2016 21
2017 36
2018 24
2019 17
2020 11
2021 12
2022 7
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162 results

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Filters applied: Meta-Analysis, Review, Systematic Review, in the last 10 years. Clear all
Page 1
Tapentadol.
[No authors listed] [No authors listed] 2023 Dec 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Dec 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30835408 Free Books & Documents. Review.
Newborn infants seem to be particularly sensitive to the effects of even small dosages of narcotic analgesics.[1] Little information is available on the use of tapentadol during breastfeeding. Because it has opioid agonist activity, an alternate drug is preferred, especial …
Newborn infants seem to be particularly sensitive to the effects of even small dosages of narcotic analgesics.[1] Little information is avai …
Tapentadol: A Review of Experimental Pharmacology Studies, Clinical Trials, and Recent Findings.
Alshehri FS. Alshehri FS. Drug Des Devel Ther. 2023 Mar 21;17:851-861. doi: 10.2147/DDDT.S402362. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 36974332 Free PMC article. Review.
Tapentadol is an analgesic compound that acts centrally to attenuate pain. ...Compared to tramadol and other opioids, tapentadol is associated with fewer adverse effects than tramadol. Tapentadol is a new alternative to treat acute, chronic, and neuropathic p …
Tapentadol is an analgesic compound that acts centrally to attenuate pain. ...Compared to tramadol and other opioids, tapentadol …
Tapentadol: an overview of the safety profile.
Polati E, Canonico PL, Schweiger V, Collino M. Polati E, et al. J Pain Res. 2019 May 16;12:1569-1576. doi: 10.2147/JPR.S190154. eCollection 2019. J Pain Res. 2019. PMID: 31190968 Free PMC article. Review.
Noteworthy, MOR activation with tapentadol is markedly lower compared with that exerted by classical opioids, thus likely resulting in fewer opioid-related adverse effects. In this review, we discuss current safety data on tapentadol, with a focus on some specific e …
Noteworthy, MOR activation with tapentadol is markedly lower compared with that exerted by classical opioids, thus likely resulting i …
Tapentadol for the management of cancer pain in adults: an update.
Boland JW. Boland JW. Curr Opin Support Palliat Care. 2023 Jun 1;17(2):90-97. doi: 10.1097/SPC.0000000000000641. Epub 2023 Mar 15. Curr Opin Support Palliat Care. 2023. PMID: 36919687 Review.
PURPOSE OF REVIEW: Tapentadol is the first of a new class of analgesics, having synergistic -opioid receptor agonist and noradrenaline reuptake inhibitory actions. ...This review describes all randomized and recent nonrandomized studies of tapentadol in adults with …
PURPOSE OF REVIEW: Tapentadol is the first of a new class of analgesics, having synergistic -opioid receptor agonist and noradrenalin …
Tapentadol Versus Tramadol: A Narrative and Comparative Review of Their Pharmacological, Efficacy and Safety Profiles in Adult Patients.
Roulet L, Rollason V, Desmeules J, Piguet V. Roulet L, et al. Drugs. 2021 Jul;81(11):1257-1272. doi: 10.1007/s40265-021-01515-z. Epub 2021 Jul 1. Drugs. 2021. PMID: 34196947 Free PMC article.
We conducted a narrative review of the literature to compare the pharmacological, efficacy and safety profiles of tapentadol and tramadol, and to assess the clinical interest of tapentadol in adult patients. Tapentadol and tramadol share a mixed mechanism of …
We conducted a narrative review of the literature to compare the pharmacological, efficacy and safety profiles of tapentadol and tram …
Tapentadol Prolonged Release: A Review in Pain Management.
Deeks ED. Deeks ED. Drugs. 2018 Nov;78(17):1805-1816. doi: 10.1007/s40265-018-1007-2. Drugs. 2018. PMID: 30471002 Free PMC article. Review.
Tapentadol prolonged release (tapentadol PR) [Palexia() SR in EU] is a long-acting tablet formulation of the strong central analgesic tapentadol, which acts as both a mu-opioid receptor (MOR) agonist and a noradrenaline reuptake inhibitor. ...Severe back pain …
Tapentadol prolonged release (tapentadol PR) [Palexia() SR in EU] is a long-acting tablet formulation of the strong central an …
Appropriate use of tapentadol: focus on the optimal tapering strategy.
Vellucci R, Fornasari D. Vellucci R, et al. Curr Med Res Opin. 2023 Jan;39(1):123-129. doi: 10.1080/03007995.2022.2148459. Epub 2022 Nov 25. Curr Med Res Opin. 2023. PMID: 36427080 Free article. Review.
RESULTS: The review discusses the use and discontinuation of opioids in general, as well clinical data on discontinuation of tapentadol specifically. We provide a flow chart, which can be used by clinicians in the context of their own clinical experience to appropriately t …
RESULTS: The review discusses the use and discontinuation of opioids in general, as well clinical data on discontinuation of tapentadol …
Tapentadol: an effective option for the treatment of back pain.
Coluzzi F, Polati E, Freo U, Grilli M. Coluzzi F, et al. J Pain Res. 2019 May 16;12:1521-1528. doi: 10.2147/JPR.S190176. eCollection 2019. J Pain Res. 2019. PMID: 31190963 Free PMC article. Review.
This narrative review discusses the rationale for the use of tapentadol in both low back pain and neck pain and presents available clinical data. Overall, data show that tapentadol prolonged release is a well-grounded treatment for chronic back pain, sustained by a …
This narrative review discusses the rationale for the use of tapentadol in both low back pain and neck pain and presents available cl …
Tapentadol for neuropathic pain: a review of clinical studies.
Freo U, Romualdi P, Kress HG. Freo U, et al. J Pain Res. 2019 May 16;12:1537-1551. doi: 10.2147/JPR.S190162. eCollection 2019. J Pain Res. 2019. PMID: 31190965 Free PMC article. Review.
In randomized controlled trials, tapentadol has proved to be effective in relieving NP in diabetic peripheral neuropathy and in chronic low back pain. ...This narrative review aims to provide clinicians with a broad overview of tapentadol effects on NP....
In randomized controlled trials, tapentadol has proved to be effective in relieving NP in diabetic peripheral neuropathy and in chron …
Toxicity of tapentadol: a systematic review.
Channell JS, Schug S. Channell JS, et al. Pain Manag. 2018 Sep 1;8(5):327-339. doi: 10.2217/pmt-2018-0027. Epub 2018 Aug 6. Pain Manag. 2018. PMID: 30079795 Review.
BACKGROUND: Tapentadol is a novel atypical opioid. Anecdotal evidence suggests that tapentadol has a lower toxicity than conventional opioids. ...Tapentadol is unlikely to cause serotonin syndrome. The toxicity of tapentadol is significantly less than …
BACKGROUND: Tapentadol is a novel atypical opioid. Anecdotal evidence suggests that tapentadol has a lower toxicity than conve …
162 results