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Quoted phrase not found in phrase index: "Tapered toe"
Page 1
Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial.
van Schaik M, Arends EJ, Soonawala D, van Ommen E, de Leeuw K, Limper M, van Paassen P, Huizinga TWJ, Toes REM, van Kooten C, Rotmans JI, Rabelink TJ, Teng YKO. van Schaik M, et al. Trials. 2022 Nov 12;23(1):939. doi: 10.1186/s13063-022-06874-w. Trials. 2022. PMID: 36371234 Free PMC article.
Safety endpoints include the incidence of adverse events, with a special interest in infections. DISCUSSION: The Synbiose 2 trial is the first multicenter phase 3 clinical trial investigating combined B cell targeted therapy in SLE, including lupus nephritis. …
Safety endpoints include the incidence of adverse events, with a special interest in infections. DISCUSSION: The Synbiose 2 trial is …
Rheumatoid myositis leading to acute lower extremity compartment syndrome: a case-based review.
Jo D, Pompa T, Khalil A, Kong F, Wetz R, Goldstein M. Jo D, et al. Clin Rheumatol. 2015 Oct;34(10):1813-6. doi: 10.1007/s10067-014-2657-4. Epub 2014 May 9. Clin Rheumatol. 2015. PMID: 24810700 Review.
The patient suffered sensory loss in the right foot and decreased strength in the toes. Lab tests revealed elevated creatine kinase, ESR, and anti-rheumatoid factor antibody titers. ...The muscle biopsy showed diffuse mononuclear cell infiltration as well as perivascular a …
The patient suffered sensory loss in the right foot and decreased strength in the toes. Lab tests revealed elevated creatine kinase, …
In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response.
de Moel EC, Derksen VFAM, Trouw LA, Bang H, Collée G, Lard LR, Ramiro S, Huizinga TWJ, Allaart CF, Toes REM, van der Woude D. de Moel EC, et al. Arthritis Res Ther. 2019 Jan 18;21(1):28. doi: 10.1186/s13075-019-1815-0. Arthritis Res Ther. 2019. PMID: 30658699 Free PMC article. Clinical Trial.

Following treatment escalation, autoantibody levels dropped markedly, while they rose following tapering: RF IgM levels, a representative autoantibody, dropped 10% after restarting prednisone and rose 15% aU/mL after tapering MTX (p < 0.0001). ...This suggests th

Following treatment escalation, autoantibody levels dropped markedly, while they rose following tapering: RF IgM levels, a representa …
The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus.
Kraaij T, Kamerling SWA, de Rooij ENM, van Daele PLA, Bredewold OW, Bakker JA, Bajema IM, Scherer HU, Toes REM, Huizinga TJW, Rabelink TJ, van Kooten C, Teng YKO. Kraaij T, et al. J Autoimmun. 2018 Jul;91:45-54. doi: 10.1016/j.jaut.2018.03.003. Epub 2018 Apr 7. J Autoimmun. 2018. PMID: 29636274 Clinical Trial.
RTX + BLM appeared to be safe and achieved clinically significant responses: low lupus disease activity state was achieved in 10 patients, renal responses in 11 patients and concomitant immunosuppressive medication was tapered in 14 out of the 16 patients. CONCLUSIONS: Thi …
RTX + BLM appeared to be safe and achieved clinically significant responses: low lupus disease activity state was achieved in 10 patients, r …
Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.
de Moel EC, Derksen VFAM, Stoeken G, Trouw LA, Bang H, Goekoop RJ, Speyer I, Huizinga TWJ, Allaart CF, Toes REM, van der Woude D. de Moel EC, et al. Arthritis Res Ther. 2018 Feb 26;20(1):33. doi: 10.1186/s13075-018-1520-4. Arthritis Res Ther. 2018. PMID: 29482627 Free PMC article. Clinical Trial.
For long-term sustained DFR there was no longer an association with the breadth of the autoantibody response. When assessing autoantibodies at the moment of tapering, similar trends were observed. CONCLUSIONS: A broad baseline autoantibody profile is associated with a bett …
For long-term sustained DFR there was no longer an association with the breadth of the autoantibody response. When assessing autoantibodies …
Zoster myelitis in sickle cell anemia.
Mousali YM, Sobhi EM, Makkawi SO. Mousali YM, et al. Neurosciences (Riyadh). 2011 Jul;16(3):273-5. Neurosciences (Riyadh). 2011. PMID: 21677622
On the fifth day, examination revealed power of 1/5 on the right leg, and 4/5 on the left leg, there was proximal and distal increased tone and brisk reflexes and up going toe on the right side with sensory level at T4-T6. An MRI of the thoracolumbar spine showed high sign …
On the fifth day, examination revealed power of 1/5 on the right leg, and 4/5 on the left leg, there was proximal and distal increased tone …
A case of eosinophilic polyangiitis with granulomatosis that evolved to cardiac arrest due to advanced atrioventricular block.
Sakurai Y, Oshikata C, Katayama T, Takagi S, Kaneko Y, Yo K, Kaneko T, Kubota H, Matsubara T, Tsurikisawa N. Sakurai Y, et al. Nagoya J Med Sci. 2023 Feb;85(1):171-178. doi: 10.18999/nagjms.85.1.171. Nagoya J Med Sci. 2023. PMID: 36923623 Free PMC article.
At age 28, she was diagnosed with eosinophilic gastroenteritis without the diagnosis of EGPA and was started on a systemic steroid and had maintenance daily dose of 2.5 mg after gradually tapered. She had experiencing dizziness and palpitations 2 weeks after discontinuatio …
At age 28, she was diagnosed with eosinophilic gastroenteritis without the diagnosis of EGPA and was started on a systemic steroid and had m …
Treatment of Thromboangiitis Obliterans Using Smoking Cessation and Far-infrared Therapy: A Case Study.
Chiang IH, Chen SG, Tzeng YS. Chiang IH, et al. Ostomy Wound Manage. 2017 Jul;63(7):20-23. Ostomy Wound Manage. 2017. PMID: 28759424 Free article.
Claudication with severe tenderness of both legs and an ischemic ulcer over the right big toe were noted. After surgical debridement of the devitalized tissue, the patient received FIR therapy (5-25 m, peak at 8.2 m) applied 25 cm above the surface of the ischemic wound fo …
Claudication with severe tenderness of both legs and an ischemic ulcer over the right big toe were noted. After surgical debridement …
A case of ANCA-associated systemic vasculitis induced by atorvastatin.
Haroon M, Devlin J. Haroon M, et al. Clin Rheumatol. 2008 Dec;27 Suppl 2:S75-7. doi: 10.1007/s10067-008-1020-z. Epub 2008 Oct 7. Clin Rheumatol. 2008. PMID: 18839266
He was treated with three 500 mg doses of methylprednisolone, followed by slowly tapering dose of oral corticosteroids from 30 mg once daily (OD). He was also started on azathioprin (2.5 mg/kg). ...He is currently on a tapering regimen of corticosteroids (7 mg OD), …
He was treated with three 500 mg doses of methylprednisolone, followed by slowly tapering dose of oral corticosteroids from 30 mg onc …
Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs.
de Moel EC, Rech J, Mahler M, Roth J, Vogl T, Schouffoer A, Goekoop RJ, Huizinga TWJ, Allaart CF, Toes REM, Schett G, van der Woude D. de Moel EC, et al. Arthritis Res Ther. 2019 Dec 5;21(1):268. doi: 10.1186/s13075-019-2064-y. Arthritis Res Ther. 2019. PMID: 31805992 Free PMC article.

Patients from the RETRO study had established RA in stable remission (DAS28 < 2.6) and either tapered by 50% or stopped (biological or conventional) DMARDs. Circulating calprotectin at the tapering time point was determined by ELISA, and its predictive value for

Patients from the RETRO study had established RA in stable remission (DAS28 < 2.6) and either tapered by 50% or stopped (biologica

19 results