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Page 1
Cutaneous manifestations of monoclonal gammopathy.
Claveau JS, Wetter DA, Kumar S. Claveau JS, et al. Blood Cancer J. 2022 Apr 11;12(4):58. doi: 10.1038/s41408-022-00661-1. Blood Cancer J. 2022. PMID: 35411042 Free PMC article. Review.
These disorders include POEMS syndrome, light chain amyloidosis, Schnitzler syndrome, scleromyxedema and TEMPI syndrome. This article provides a review of clinical manifestations, diagnostics criteria, natural evolution, pathogenesis, and treatment of these cutaneou …
These disorders include POEMS syndrome, light chain amyloidosis, Schnitzler syndrome, scleromyxedema and TEMPI syndrome. This …
TEMPI Syndrome: Update on Clinical Features, Management, and Pathogenesis.
Xu J, Liu W, Fan F, Zhang B, Zhao F, Hu Y, Sun C. Xu J, et al. Front Endocrinol (Lausanne). 2022 May 19;13:886961. doi: 10.3389/fendo.2022.886961. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35663307 Free PMC article. Review.
In this review, we summarize the reported clinical characteristics of TEMPI syndrome and discuss the current and potential treatment options for patients with TEMPI syndrome, including those with relapsed/refractory disease. Furthermore, we provide an …
In this review, we summarize the reported clinical characteristics of TEMPI syndrome and discuss the current and potential tre …
TEMPI Syndrome: Erythrocytosis in Plasma Cell Dyscrasia.
Zhang X, Fang M. Zhang X, et al. Clin Lymphoma Myeloma Leuk. 2018 Nov;18(11):724-730. doi: 10.1016/j.clml.2018.07.284. Epub 2018 Aug 9. Clin Lymphoma Myeloma Leuk. 2018. PMID: 30100329 Review.
TEMPI syndrome is often misdiagnosed as other causes of erythrocytosis, resulting in a delayed diagnosis and further clinical deterioration. The aim of the present review was to present the clinical and biologic features of TEMPI syndrome, highlighting
TEMPI syndrome is often misdiagnosed as other causes of erythrocytosis, resulting in a delayed diagnosis and further clinical
Comprehensive Next-Generation Sequencing Testing in a Patient with TEMPI Syndrome.
Nunes Rosado FG, Lekovic D, Gagan J, Malter J, Chen W, Sykes DB. Nunes Rosado FG, et al. Lab Med. 2023 Sep 5;54(5):546-549. doi: 10.1093/labmed/lmad003. Lab Med. 2023. PMID: 36864546
TEMPI syndrome is a new and poorly understood disease that is currently considered a type of plasma cell neoplasm with paraneoplastic manifestations. ...Here we present a new case of TEMPI syndrome, discuss results of a next-generation sequencing (NGS)
TEMPI syndrome is a new and poorly understood disease that is currently considered a type of plasma cell neoplasm with paraneo
TEMPI syndrome: A clinical, light-microscopic and phenotypic evaluation with review of the literature.
Kalomeris TA, Grossman ME, Tepler J, Magro CM. Kalomeris TA, et al. J Cutan Pathol. 2024 Apr;51(4):299-305. doi: 10.1111/cup.14572. Epub 2023 Dec 16. J Cutan Pathol. 2024. PMID: 38102936 Review.
Although telangiectasias are the hallmark of this syndrome, skin biopsies are rarely performed. We aim to further characterize TEMPI syndrome through the evaluationof a skin biopsy. METHODS: We reviewed the histopathology and immunophenotypic profile of a skin biops …
Although telangiectasias are the hallmark of this syndrome, skin biopsies are rarely performed. We aim to further characterize TEMPI
Long-Term Complete Clinical and Hematological Response With Bortezomib: The Report of a Case With TEM(P)I Syndrome and a Review of the Literature.
Undar L, Atas U, Iltar U, Salim O, Yucel OK, Alpsoy E. Undar L, et al. Clin Lymphoma Myeloma Leuk. 2022 Sep;22(9):702-707. doi: 10.1016/j.clml.2022.04.018. Epub 2022 Apr 22. Clin Lymphoma Myeloma Leuk. 2022. PMID: 35624059 Review.
TEMPI syndrome was first defined in 2011 and classified as a plasma cell neoplasm with associated paraneoplastic syndrome in 2016. ...Here, we also review the clinical features of TEMPI syndrome, differential diagnosis and available treatment options,
TEMPI syndrome was first defined in 2011 and classified as a plasma cell neoplasm with associated paraneoplastic syndrome in 2
Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist.
Rosado FG, Oliveira JL, Sohani AR, Schroyens W, Sykes DB, Kenderian SS, Lacy MQ, Kyle RA, Hoyer JD. Rosado FG, et al. Mod Pathol. 2015 Mar;28(3):367-72. doi: 10.1038/modpathol.2014.117. Epub 2014 Sep 12. Mod Pathol. 2015. PMID: 25216227 Free article.
To date, 11 patients have been identified. This is the first morphologic review of TEMPI syndrome bone marrow samples, in order to define pathologic features that may aid in the recognition of the syndrome and to identify post-therapy changes. ...Findings of myelopr …
To date, 11 patients have been identified. This is the first morphologic review of TEMPI syndrome bone marrow samples, in orde …
The First Case of TEMPI Syndrome in Japan.
Shizuku T, Matsui K, Yagi S, Iwabuchi S. Shizuku T, et al. Intern Med. 2020 Jul 15;59(14):1741-1744. doi: 10.2169/internalmedicine.3547-19. Epub 2020 Apr 16. Intern Med. 2020. PMID: 32295999 Free PMC article.
TEMPI syndrome, a disease entity comprising telangiectasia, erythrocytosis with high erythropoietin, monoclonal gammopathy, perinephric fluid collection, and intrapulmonary shunting, was first described by Sykes et al. in 2011. ...In addition to ascites, he had tela
TEMPI syndrome, a disease entity comprising telangiectasia, erythrocytosis with high erythropoietin, monoclonal gammopathy, pe
Subcutaneous bortezomib for treatment of TEMPI syndrome.
Jasim S, Mahmud G, Bastani B, Fesler M. Jasim S, et al. Clin Lymphoma Myeloma Leuk. 2014 Dec;14(6):e221-3. doi: 10.1016/j.clml.2014.07.004. Epub 2014 Jul 15. Clin Lymphoma Myeloma Leuk. 2014. PMID: 25172534 No abstract available.