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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 1
1973 1
1975 2
1976 3
1977 3
1978 1
1979 1
1981 1
1982 3
1983 2
1984 1
1985 5
1986 4
1987 6
1988 4
1989 3
1990 5
1991 9
1992 3
1993 8
1994 5
1995 5
1996 6
1997 6
1998 6
1999 4
2000 1
2001 3
2002 4
2003 6
2004 6
2005 3
2006 10
2007 7
2008 3
2009 3
2010 9
2011 6
2012 9
2013 1
2014 6
2015 6
2016 2
2017 4
2018 2
2019 7
2020 7
2021 3
2022 3
2023 5
2024 1

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201 results

Results by year

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Page 1
Early events during neoplastic progression in Barrett's esophagus.
Reid BJ. Reid BJ. Cancer Biomark. 2010;9(1-6):307-24. doi: 10.3233/CBM-2011-0162. Cancer Biomark. 2010. PMID: 22112482 Free PMC article. Review.
These spatial studies have provided the basis for prospective cohort studies of biomarkers, including DNA content abnormalities (tetraploidy, aneuploidy) and a biomarker panel of 9p LOH, 17p LOH and DNA content abnormalities. ...
These spatial studies have provided the basis for prospective cohort studies of biomarkers, including DNA content abnormalities (tetraplo
Polyploidy, aneuploidy and the evolution of cancer.
Merlo LM, Wang LS, Pepper JW, Rabinovitch PS, Maley CC. Merlo LM, et al. Adv Exp Med Biol. 2010;676:1-13. doi: 10.1007/978-1-4419-6199-0_1. Adv Exp Med Biol. 2010. PMID: 20687466 Review.
We also review evidence from Barrett's esophagus, a pre-malignant condition, demonstrating that tetraploidy and aneuploidy are correlated with an increased risk of progression to cancer. ...
We also review evidence from Barrett's esophagus, a pre-malignant condition, demonstrating that tetraploidy and aneuploidy are correl …
Tetraploidy/near-tetraploidy acute myeloid leukemia.
Huang L, Wang SA, DiNardo C, Li S, Hu S, Xu J, Zhou W, Goswami M, Medeiros LJ, Tang G. Huang L, et al. Leuk Res. 2017 Feb;53:20-27. doi: 10.1016/j.leukres.2016.11.016. Epub 2016 Dec 2. Leuk Res. 2017. PMID: 27951415
Colorectal cancer: role of commensal bacteria and bystander effects.
Wang X, Huycke MM. Wang X, et al. Gut Microbes. 2015;6(6):370-6. doi: 10.1080/19490976.2015.1103426. Gut Microbes. 2015. PMID: 26727419 Free PMC article. Review.
In this Addendum we review recent work from our laboratory that explore mechanisms by which intestinal commensals polarize colon macrophages to an M1 phenotype to generate a bystander effect (BSE) that leads to mutations, spindle malfunction, cell cycle arrest, tetraploidy
In this Addendum we review recent work from our laboratory that explore mechanisms by which intestinal commensals polarize colon macrophages …
Biomarkers in Barrett's esophagus.
Reid BJ, Blount PL, Rabinovitch PS. Reid BJ, et al. Gastrointest Endosc Clin N Am. 2003 Apr;13(2):369-97. doi: 10.1016/s1052-5157(03)00006-0. Gastrointest Endosc Clin N Am. 2003. PMID: 12916666 Review.
Some studies have even suggested that endoscopic biopsy surveillance using dysplasia may not be worthwhile. Currently, flow cytometric tetraploidy and aneuploidy have progressed furthest in biomarker validation (see Table 1). With proper handling, endoscopic biopsy specime …
Some studies have even suggested that endoscopic biopsy surveillance using dysplasia may not be worthwhile. Currently, flow cytometric te
The prognostic implications of tetraploidy/near-Tetraploidy in acute myeloid leukemia: a case series and systematic review of the literature.
Xie J, Nachabe A, Hathaway LJ, Farah B, Berbari B, Li Y, Brown TC, Schmid JL, Socola F, Saba NS, Safah H. Xie J, et al. Leuk Lymphoma. 2021 Jan;62(1):203-210. doi: 10.1080/10428194.2020.1817435. Epub 2020 Sep 29. Leuk Lymphoma. 2021. PMID: 32993375 Review.
The prognostic significance and optimal management of tetraploidy/near-tetraploidy acute myeloid leukemia (T/NT AML) remains unclear given its limited data. ...
The prognostic significance and optimal management of tetraploidy/near-tetraploidy acute myeloid leukemia (T/NT AML) remains u …
Barrett's esophagus and its progression to adenocarcinoma.
Maley CC, Rustgi AK. Maley CC, et al. J Natl Compr Canc Netw. 2006 Apr;4(4):367-74. doi: 10.6004/jnccn.2006.0031. J Natl Compr Canc Netw. 2006. PMID: 16569389 Review.
Many of the genetic lesions involved in BE neoplastic progression are known, including loss of CDKN2A (p16) and TP53 (p53) and the development of tetraploidy and aneuploidy. Intensive endoscopic surveillance has been shown to improve survival although it can be difficult t …
Many of the genetic lesions involved in BE neoplastic progression are known, including loss of CDKN2A (p16) and TP53 (p53) and the developme …
Polyploidy is widespread in Microsporidia.
Khalaf A, Lawniczak MKN, Blaxter ML, Jaron KS. Khalaf A, et al. Microbiol Spectr. 2024 Feb 6;12(2):e0366923. doi: 10.1128/spectrum.03669-23. Epub 2024 Jan 12. Microbiol Spectr. 2024. PMID: 38214524 Free PMC article.
Understanding a genome's ploidy is crucial in order to assemble it effectively and may also be relevant for better understanding a parasite's behavior and life cycle. We show that tetraploidy is present in at least six species in Microsporidia and that these polyploidizati …
Understanding a genome's ploidy is crucial in order to assemble it effectively and may also be relevant for better understanding a parasite' …
Dissecting the genomic complexity underlying medulloblastoma.
Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Tonini GP, Schüller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann MU, Frühwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Collins VP, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P. Jones DT, et al. Nature. 2012 Aug 2;488(7409):100-5. doi: 10.1038/nature11284. Nature. 2012. PMID: 22832583 Free PMC article.
Here we describe an integrative deep-sequencing analysis of 125 tumour-normal pairs, conducted as part of the International Cancer Genome Consortium (ICGC) PedBrain Tumor Project. Tetraploidy was identified as a frequent early event in Group 3 and 4 tumours, and a positive …
Here we describe an integrative deep-sequencing analysis of 125 tumour-normal pairs, conducted as part of the International Cancer Genome Co …
Chromosomal abnormalities associated with neural tube defects (I): full aneuploidy.
Chen CP. Chen CP. Taiwan J Obstet Gynecol. 2007 Dec;46(4):325-35. doi: 10.1016/S1028-4559(08)60002-9. Taiwan J Obstet Gynecol. 2007. PMID: 18182338 Free article. Review.
This article provides an overview of chromosomal abnormalities associated with NTDs in embryos, fetuses, and newborn patients, and a comprehensive review of numerical chromosomal abnormalities associated with NTDs, such as trisomy 18, trisomy 13, triploidy, trisomy 9, trisomy 2, …
This article provides an overview of chromosomal abnormalities associated with NTDs in embryos, fetuses, and newborn patients, and a compreh …
201 results