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497 results

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Page 1
Thrombin generation assay: the present and the future.
Wu Y, Lu Y, Zhang J. Wu Y, et al. Blood Coagul Fibrinolysis. 2023 Jan 1;34(1):1-7. doi: 10.1097/MBC.0000000000001170. Epub 2022 Oct 20. Blood Coagul Fibrinolysis. 2023. PMID: 36598375 Review.
The need for a more precise test that replicates the in vivo hemostatic conditions is increasingly being recognized. Up to now, the thrombin generation assay (TGA) has become the most reliable approach to evaluate the status of coagulation activation. ...
The need for a more precise test that replicates the in vivo hemostatic conditions is increasingly being recognized. Up to now, the throm …
Thrombin generation assay as a biomarker of cardiovascular outcomes and mortality: A narrative review.
Ferreira LGR, Figueiredo RC, das Graças Carvalho M, Rios DRA. Ferreira LGR, et al. Thromb Res. 2022 Dec;220:107-115. doi: 10.1016/j.thromres.2022.10.007. Epub 2022 Oct 13. Thromb Res. 2022. PMID: 36334397 Review.
Considering that CVDs present in their pathophysiology a strong interaction between inflammation and hemostasis, thrombin, a key enzyme in the clotting process can be thought as a possible biomarker of cardiovascular risk. The thrombin generation assay (TGA) …
Considering that CVDs present in their pathophysiology a strong interaction between inflammation and hemostasis, thrombin, a key enzyme in t …
Thrombin Generation Assay and Its Application in the Clinical Laboratory.
Tripodi A. Tripodi A. Clin Chem. 2016 May;62(5):699-707. doi: 10.1373/clinchem.2015.248625. Epub 2016 Mar 8. Clin Chem. 2016. PMID: 26955824 Review.
BACKGROUND: A gap exists between in vivo and ex vivo coagulation when investigated by use of the coagulation tests prothrombin time (PT) and activated partial thromboplastin time (APTT). The thrombin generation assay (TGA) has been developed to fill this gap. …
BACKGROUND: A gap exists between in vivo and ex vivo coagulation when investigated by use of the coagulation tests prothrombin time (PT) and …
Automated Thrombin Generation Assay for Rivaroxaban, Apixaban, and Edoxaban Measurements.
Meihandoest T, Studt JD, Mendez A, Alberio L, Fontana P, Wuillemin WA, Schmidt A, Graf L, Gerber B, Maeder GM, Bovet C, Sauter TC, Nagler M. Meihandoest T, et al. Front Cardiovasc Med. 2021 Sep 9;8:717939. doi: 10.3389/fcvm.2021.717939. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34568459 Free PMC article.
Background: The thrombin generation assay (TG) is a promising approach to measure the degree of anticoagulation in patients treated with direct oral anticoagulants (DOAC). ...
Background: The thrombin generation assay (TG) is a promising approach to measure the degree of anticoagulation in pati …
Factor XII deficiency evaluated by thrombin generation assay.
Feugray G, Kasonga F, Chamouni P, Barbay V, Fresel M, Hélène Chretien M, Brunel S, Le Cam Duchez V, Billoir P. Feugray G, et al. Clin Biochem. 2022 Feb;100:42-47. doi: 10.1016/j.clinbiochem.2021.11.014. Epub 2021 Nov 26. Clin Biochem. 2022. PMID: 34843733 Clinical Trial.
FXII deficiency is not associated with bleeding risk unlike other coagulation factors. MATERIALS/METHODS: We investigated thrombin generation assay (TGA) profile modification in FXII deficiency and the correlation with TGA and deficiency severity. ...
FXII deficiency is not associated with bleeding risk unlike other coagulation factors. MATERIALS/METHODS: We investigated thrombin …
[Thrombin generation assay in autoimmune disease].
Billoir P, Le Cam Duchez V, Miranda S, Richard V, Benhamou Y. Billoir P, et al. Rev Med Interne. 2021 Dec;42(12):862-868. doi: 10.1016/j.revmed.2021.06.006. Epub 2021 Jun 24. Rev Med Interne. 2021. PMID: 34175144 French.
Thrombin generation assay (TGA) is a useful tool to evaluate the initiation, propagation and inhibition of coagulation. ...
Thrombin generation assay (TGA) is a useful tool to evaluate the initiation, propagation and inhibition of coagulation. …
Thrombin Generation Assay and Hemostatic Profile for Elucidating Hypercoagulability in Endogenous Canine Hyperadrenocorticism.
Vargas-Mora SE, Romão FG, Dos Santos B, Carvalho MDG, Duarte RCF, De Marco Bernardes V, Lopes PA, Takahira RK. Vargas-Mora SE, et al. Top Companion Anim Med. 2021 Nov;45:100581. doi: 10.1016/j.tcam.2021.100581. Epub 2021 Sep 10. Top Companion Anim Med. 2021. PMID: 34509666
Canine hyperadrenocorticism is a common endocrine disorder caused by chronic secretion of glucocorticoid, often associated with hypercoagulability and secondary thrombosis. The thrombin generation assay (TGA) evaluates hemostasis globally by measuring endogen …
Canine hyperadrenocorticism is a common endocrine disorder caused by chronic secretion of glucocorticoid, often associated with hypercoagula …
Evaluation of thrombin generation assay in factor XI deficiency.
Kasonga F, Feugray G, Chamouni P, Barbay V, Fresel M, Chretien MH, Brunel S, Le Cam Duchez V, Billoir P. Kasonga F, et al. Clin Chim Acta. 2021 Dec;523:348-354. doi: 10.1016/j.cca.2021.10.021. Epub 2021 Oct 17. Clin Chim Acta. 2021. PMID: 34670127
INTRODUCTION: Factor XI (FXI) deficiency is characterized by a lack of correlation between FXI plasma levels and the occurrence of hemorrhagic events. The main objective of our study was to determine whether thrombin generation assay (TGA) could be used to as …
INTRODUCTION: Factor XI (FXI) deficiency is characterized by a lack of correlation between FXI plasma levels and the occurrence of hemorrhag …
497 results