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1974 1
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1982 3
1983 5
1984 8
1985 2
1986 7
1987 7
1988 4
1989 14
1990 8
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1996 10
1997 10
1998 13
1999 18
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2006 30
2007 30
2008 27
2009 23
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951 results

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Quoted phrase not found in phrase index: "Thrombocythemia 3"
Page 1
Primary myelofibrosis: 2023 update on diagnosis, risk-stratification, and management.
Tefferi A. Tefferi A. Am J Hematol. 2023 May;98(5):801-821. doi: 10.1002/ajh.26857. Epub 2023 Feb 6. Am J Hematol. 2023. PMID: 36680511 Free article. Review.
MUTATIONS: SRSF2, ASXL1, and U2AF1-Q157 mutations predict inferior survival in PMF; RAS/CBL mutations predict resistance to ruxolitinib therapy. ...RISK STRATIFICATION: Contemporary prognostic systems include GIPSS (genetically-inspired prognostic scoring
MUTATIONS: SRSF2, ASXL1, and U2AF1-Q157 mutations predict inferior survival in PMF; RAS/CBL mutations predict resistance to ru …
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T. Tefferi A, et al. Am J Hematol. 2023 Sep;98(9):1465-1487. doi: 10.1002/ajh.27002. Epub 2023 Jun 26. Am J Hematol. 2023. PMID: 37357958 Review.
CYTOGENETICS: Abnormal karyotype is seen in 15%-20% of patients with the most frequent sole abnormalities being +9 (5%), loss of chromosome Y (4%), +8 (3%), and 20q- (3%). MUTATIONS: Over 50% of patients harbor DNA sequence variants/mutations other than JAK2, with t …
CYTOGENETICS: Abnormal karyotype is seen in 15%-20% of patients with the most frequent sole abnormalities being +9 (5%), loss of chromosome …
Mutation-enhanced international prognostic systems for essential thrombocythaemia and polycythaemia vera.
Tefferi A, Guglielmelli P, Lasho TL, Coltro G, Finke CM, Loscocco GG, Sordi B, Szuber N, Rotunno G, Pacilli A, Hanson CA, Ketterling RP, Pardanani A, Gangat N, Vannucchi AM. Tefferi A, et al. Br J Haematol. 2020 Apr;189(2):291-302. doi: 10.1111/bjh.16380. Epub 2020 Jan 16. Br J Haematol. 2020. PMID: 31945802 Free article.
Survival prediction in essential thrombocythaemia (ET) and polycythaemia vera (PV) is currently based on clinically-derived variables; we examined the possibility of integrating genetic information for predicting survival. ...HR-based risk point allocation al …
Survival prediction in essential thrombocythaemia (ET) and polycythaemia vera (PV) is currently based on clinically-derived va …
A clinical-molecular prognostic model to predict survival in patients with post polycythemia vera and post essential thrombocythemia myelofibrosis.
Passamonti F, Giorgino T, Mora B, Guglielmelli P, Rumi E, Maffioli M, Rambaldi A, Caramella M, Komrokji R, Gotlib J, Kiladjian JJ, Cervantes F, Devos T, Palandri F, De Stefano V, Ruggeri M, Silver RT, Benevolo G, Albano F, Caramazza D, Merli M, Pietra D, Casalone R, Rotunno G, Barbui T, Cazzola M, Vannucchi AM. Passamonti F, et al. Leukemia. 2017 Dec;31(12):2726-2731. doi: 10.1038/leu.2017.169. Epub 2017 May 31. Leukemia. 2017. PMID: 28561069
Median survival of the whole cohort was 9.3 years (95% CI: 8-not reached-NR-). Through penalized Cox regressions we identified negative predictors of survival and according to beta risk coefficients we assigned 2 points to hemoglobin level <11 g/dl, to circulatin …
Median survival of the whole cohort was 9.3 years (95% CI: 8-not reached-NR-). Through penalized Cox regressions we identified negati …
Myeloproliferative Neoplasms with Monocytosis.
Morsia E, Gangat N. Morsia E, et al. Curr Hematol Malig Rep. 2022 Feb;17(1):46-51. doi: 10.1007/s11899-021-00660-2. Epub 2021 Nov 13. Curr Hematol Malig Rep. 2022. PMID: 34773576 Review.
Prognostically relevant clinical and genetic parameters have been incorporated into mutation-enhanced scoring systems (MIPSS70-plus version 2.0, MIPSS-ET/PV). In the current review, we describe clinical and pathological features along with prognostic significance of …
Prognostically relevant clinical and genetic parameters have been incorporated into mutation-enhanced scoring systems (MIPSS70 …
Developments in diagnosis and treatment of essential thrombocythemia.
Mora B, Passamonti F. Mora B, et al. Expert Rev Hematol. 2019 Mar;12(3):159-171. doi: 10.1080/17474086.2019.1585239. Epub 2019 Mar 13. Expert Rev Hematol. 2019. PMID: 30793984 Review.
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm characterized by thrombocytosis, increased risk of thrombotic/hemorrhagic events and clonal evolution into blast phase or myelofibrosis. ...New insights into the molecular pathogenesis of the di …
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm characterized by thrombocytosis, increased risk of thr …
Essential Thrombocythemia and Polycythemia Vera: Focus on Clinical Practice.
Tefferi A, Barbui T. Tefferi A, et al. Mayo Clin Proc. 2015 Sep;90(9):1283-93. doi: 10.1016/j.mayocp.2015.05.014. Mayo Clin Proc. 2015. PMID: 26355403 Review.
Bone marrow (BM) morphologic features remain the cornerstone of diagnosis in both essential thrombocythemia (ET) and polycythemia vera (PV). In addition, recently discovered mutations, such as JAK2, CALR, and MPL, have proven useful in facilitating the diagnostic process. …
Bone marrow (BM) morphologic features remain the cornerstone of diagnosis in both essential thrombocythemia (ET) and polycythemia ver …
Essential thrombocythaemia.
Tobelem G. Tobelem G. Baillieres Clin Haematol. 1989 Jul;2(3):719-28. doi: 10.1016/s0950-3536(89)80040-x. Baillieres Clin Haematol. 1989. PMID: 2505875 Review.
Essential thrombocythaemia (ET) is a rare clonal myeloproliferative disorder characterized by a persistent increase in platelet count. ...The use of recombinant alpha-interferon has recently been proposed and is under investigation. The pathogenesis of thrombocytosis
Essential thrombocythaemia (ET) is a rare clonal myeloproliferative disorder characterized by a persistent increase in platelet count …
BCR::ABL1 negative myeloproliferative neoplasms: A review focused on essential thrombocythemia and polycythemia vera.
Khodier M, Gadó K. Khodier M, et al. Physiol Int. 2023 Aug 31;110(3):227-250. doi: 10.1556/2060.2023.00261. Print 2023 Sep 5. Physiol Int. 2023. PMID: 37651280 Review.
There are many overlapping symptoms of Philadelphia negative MPNs, such as fatigue, night sweats, hepatosplenomegaly and circulatory symptoms due to increased cell numbers. Total Symptom Score of the MPN Symptom Assessment Form is used to assess symptom burden on patients. …
There are many overlapping symptoms of Philadelphia negative MPNs, such as fatigue, night sweats, hepatosplenomegaly and circulatory symptom …
Epidemiology of the Philadelphia Chromosome-Negative Classical Myeloproliferative Neoplasms.
Shallis RM, Zeidan AM, Wang R, Podoltsev NA. Shallis RM, et al. Hematol Oncol Clin North Am. 2021 Apr;35(2):177-189. doi: 10.1016/j.hoc.2020.11.005. Epub 2021 Jan 4. Hematol Oncol Clin North Am. 2021. PMID: 33641862 Review.
Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) comprise the BCR-ABL-negative classical myeloproliferative neoplasms (MPNs). ...PV and ET have an incidence of 0.5 to 4.0 and 1.1 to 2.0 cases per 100,000 person-years, respectively, an …
Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) comprise the BCR-ABL-negative classical myelo …
951 results