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Page 1
Approaches to Biopsy and Resection Specimens from the Ampulla.
Xue Y, Reid MD. Xue Y, et al. Surg Pathol Clin. 2020 Sep;13(3):453-467. doi: 10.1016/j.path.2020.05.005. Epub 2020 Jul 15. Surg Pathol Clin. 2020. PMID: 32773194 Review.
More recently, the molecular landscape of AC has been uncovered, and has been shown to have prognostic and predictive significance. In this article, the site-specific, histologic, and genetic characteristics of ampullary carcinoma and its precursor lesions are discussed... …
More recently, the molecular landscape of AC has been uncovered, and has been shown to have prognostic and predictive significance. I …
The Relationship Between Intracholecystic Papillary-Tubular Neoplasms and Invasive Carcinoma of the Gallbladder.
Argon A, Barbet FY, Nart D. Argon A, et al. Int J Surg Pathol. 2016 Sep;24(6):504-11. doi: 10.1177/1066896916644781. Epub 2016 Apr 27. Int J Surg Pathol. 2016. PMID: 27122163
INTRODUCTION: The term intracholecystic papillary-tubular neoplasm (ICPN) is suggested by some authors for a group of exophytic lesions of the gallbladder. ...RESULTS: The incidence of ICPN was 0.61% in our series. Invasive carcinoma was observed in 56% of ca …
INTRODUCTION: The term intracholecystic papillary-tubular neoplasm (ICPN) is suggested by some authors for a group of exophyti …
Cholangiocarcinoma with intraductal tubular growth pattern versus intraductal papillary growth pattern.
Tsukahara T, Shimoyama Y, Ebata T, Yokoyama Y, Igami T, Sugawara G, Mizuno T, Yamaguchi J, Nakamura S, Nagino M. Tsukahara T, et al. Mod Pathol. 2016 Mar;29(3):293-301. doi: 10.1038/modpathol.2015.152. Epub 2016 Jan 15. Mod Pathol. 2016. PMID: 26769137 Free article.
In conclusion, the tubular growth pattern exhibited differences in some histologic indexes, in addition to a higher hepatic metastasis rate and a lower KRAS mutation frequency, compared with the papillary growth pattern, but no difference in prognosis was observed. The dis …
In conclusion, the tubular growth pattern exhibited differences in some histologic indexes, in addition to a higher hepatic metastasis rate …
Intraductal tubular neoplasms of the bile ducts.
Katabi N, Torres J, Klimstra DS. Katabi N, et al. Am J Surg Pathol. 2012 Nov;36(11):1647-55. doi: 10.1097/PAS.0b013e3182684d4f. Am J Surg Pathol. 2012. PMID: 23073323
An extraductal invasive carcinoma component was present in 7 cases, composing <25% of the tumor in 4 cases, and >75% in 1 case. It was observed by immunohistochemical analysis that the tumor cells expressed CK19, CA19-9, MUC1, and MUC6 in most cases and that SMAD4 ex …
An extraductal invasive carcinoma component was present in 7 cases, composing <25% of the tumor in 4 cases, and >75% in 1 case. It was …
Intraductal neoplasm of the intrahepatic bile duct: clinicopathological study of 24 cases.
Naito Y, Kusano H, Nakashima O, Sadashima E, Hattori S, Taira T, Kawahara A, Okabe Y, Shimamatsu K, Taguchi J, Momosaki S, Irie K, Yamaguchi R, Yokomizo H, Nagamine M, Fukuda S, Sugiyama S, Nishida N, Higaki K, Yoshitomi M, Yasunaga M, Okuda K, Kinoshita H, Nakayama M, Yasumoto M, Akiba J, Kage M, Yano H. Naito Y, et al. World J Gastroenterol. 2012 Jul 28;18(28):3673-80. doi: 10.3748/wjg.v18.i28.3673. World J Gastroenterol. 2012. PMID: 22851859 Free PMC article.
Twenty of 24 tumors (83%) were composed of a papillary structure; the same feature observed in intraductal papillary neoplasm of the bile duct (IPNB). ...In the 16 malignant cases, expression of MUC5AC showed borderline significant association with high Ki-67 LI (P = 0.062 …
Twenty of 24 tumors (83%) were composed of a papillary structure; the same feature observed in intraductal papillary neoplasm of the …
Prognostic Impact of Intra-Ampullary Papillary-Tubular Neoplasm versus Flat Dysplasia as Precursor Lesions of Ampullary Adenocarcinoma.
Han S, Jang KT, Choi DW, Choi SH, Heo JS, Han IW, Park D, Ryu Y. Han S, et al. Dig Surg. 2020;37(6):505-514. doi: 10.1159/000510961. Epub 2020 Oct 20. Dig Surg. 2020. PMID: 33080609
BACKGROUND: The aim of this study is to compare the prognostic impact of 2 precursor lesions of ampullary adenocarcinoma, intra-ampullary papillary-tubular neoplasm (IAPN) and flat dysplasia (FD). METHODS: From December 1994 to December 2012, a total of 359 patients …
BACKGROUND: The aim of this study is to compare the prognostic impact of 2 precursor lesions of ampullary adenocarcinoma, intra-ampullary pa …
Intraductal tubular neoplasm of the common bile duct.
Sato Y, Osaka H, Harada K, Sasaki M, Nakanuma Y. Sato Y, et al. Pathol Int. 2010 Jul;60(7):516-9. doi: 10.1111/j.1440-1827.2010.02550.x. Pathol Int. 2010. PMID: 20594273
Recently, biliary neoplasms resembling intraductal neoplasms of the pancreas have been documented. In this report, a rare case of intraductal tubular neoplasm (ITN) arising in the common bile duct is presented. ...Endoscopic polypectomy was performed for the lesion. …
Recently, biliary neoplasms resembling intraductal neoplasms of the pancreas have been documented. In this report, a rare case of intraducta …
Medullary carcinoma of the ampulla has distinct clinicopathologic characteristics including common association with microsatellite instability and PD-L1 expression.
Xue Y, Balci S, Pehlivanoglu B, Muraki T, Memis B, Saka B, Kim G, Bandyopadhyay S, Knight J, El-Rayes B, Kooby D, Maithel SK, Sarmiento J, Basturk O, Reid MD, Adsay V. Xue Y, et al. Hum Pathol. 2023 Jan;131:38-46. doi: 10.1016/j.humpath.2022.12.004. Epub 2022 Dec 9. Hum Pathol. 2023. PMID: 36502926
Eight were papilla Vateri-NOS (not otherwise specified) tumors, 2 were ampullary-duodenal origin, 1 had a minor intra-ampullary papillary tubular neoplasm component, and none were ampullary-ductal. Although they had pushing-border infiltration, perineural and vascul …
Eight were papilla Vateri-NOS (not otherwise specified) tumors, 2 were ampullary-duodenal origin, 1 had a minor intra-ampullary papillary …