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Page 1
The molecular basis of immuno-radiotherapy.
Koukourakis IM, Tiniakos D, Kouloulias V, Zygogianni A. Koukourakis IM, et al. Int J Radiat Biol. 2023;99(5):715-736. doi: 10.1080/09553002.2023.2144960. Epub 2022 Nov 16. Int J Radiat Biol. 2023. PMID: 36383201
This systematic review provides an overview of the basics of anti-tumor immunity and focuses on the mechanisms underlying the interplay between RT and immune anti-tumor response that set the molecular basis of immuno-RT. ...
This systematic review provides an overview of the basics of anti-tumor immunity and focuses on the mechanisms underlying the …
Racial disparities in colorectal cancer clinicopathological and molecular tumor characteristics: a systematic review.
Lawler T, Parlato L, Warren Andersen S. Lawler T, et al. Cancer Causes Control. 2024 Feb;35(2):223-239. doi: 10.1007/s10552-023-01783-y. Epub 2023 Sep 9. Cancer Causes Control. 2024. PMID: 37688643
Although emerging evidence suggests that immune markers reflecting anti-tumor immunity in the tumor microenvironment may be lower for African American cases, there is insufficient evidence to evaluate disparities in other novel markers, cancer stem cells, microRNAs, …
Although emerging evidence suggests that immune markers reflecting anti-tumor immunity in the tumor microenvironment may be lo …
The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature.
deLeeuw RJ, Kost SE, Kakal JA, Nelson BH. deLeeuw RJ, et al. Clin Cancer Res. 2012 Jun 1;18(11):3022-9. doi: 10.1158/1078-0432.CCR-11-3216. Epub 2012 Apr 17. Clin Cancer Res. 2012. PMID: 22510350 Review.
A second subpopulation of TIL, defined by forkhead box protein P3 (FoxP3) expression, has been reported to inhibit tumor immunity, resulting in decreased patient survival. On the basis of this premise, several groups are attempting to deplete FoxP3+ T cells to enhan …
A second subpopulation of TIL, defined by forkhead box protein P3 (FoxP3) expression, has been reported to inhibit tumor immunity …
Bridging Radiotherapy to Immunotherapy: The IFN-JAK-STAT Axis.
Shi LZ, Bonner JA. Shi LZ, et al. Int J Mol Sci. 2021 Nov 14;22(22):12295. doi: 10.3390/ijms222212295. Int J Mol Sci. 2021. PMID: 34830176 Free PMC article.
With the "newly" discovered immunogenic responses from RT, numerous endeavors have been undertaken to combine RT with IOs, in order to bolster anti-tumor immunity. However, the underlying mechanisms are not well defined, which is a subject of much investigation. ...
With the "newly" discovered immunogenic responses from RT, numerous endeavors have been undertaken to combine RT with IOs, in order to bolst …
Crosstalk Between Trophoblasts and Decidual Immune Cells: The Cornerstone of Maternal-Fetal Immunotolerance.
Xu L, Li Y, Sang Y, Li DJ, Du M. Xu L, et al. Front Immunol. 2021 Feb 25;12:642392. doi: 10.3389/fimmu.2021.642392. eCollection 2021. Front Immunol. 2021. PMID: 33717198 Free PMC article.
Advancement in this area will further accelerate the basic research and clinical transformation of reproductive immunity and tumor immunity....
Advancement in this area will further accelerate the basic research and clinical transformation of reproductive immunity and tumor …
A novel investigation into the negative impact of opioid use on the efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer patients.
Guo H, Li Y, Lin J, Li D, Yang J, Wang J, Mao J, Wang Y, Yan X. Guo H, et al. Int Immunopharmacol. 2024 Mar 10;129:111611. doi: 10.1016/j.intimp.2024.111611. Epub 2024 Feb 6. Int Immunopharmacol. 2024. PMID: 38325047
OTGs have the potential to be prognostic biomarkers for NSCLC patients and their role in tumor immunity needs to be further investigated....
OTGs have the potential to be prognostic biomarkers for NSCLC patients and their role in tumor immunity needs to be further in …
Effect of dendritic cell-based immunotherapy on hepatocellular carcinoma: A systematic review and meta-analysis.
Chen C, Ma YH, Zhang YT, Zhang F, Zhou N, Wang X, Liu T, Li YM. Chen C, et al. Cytotherapy. 2018 Aug;20(8):975-989. doi: 10.1016/j.jcyt.2018.06.002. Epub 2018 Jul 30. Cytotherapy. 2018. PMID: 30072299
Adverse reactions were mild. CONCLUSIONS: DC-based therapy not only enhanced anti-tumor immunity, improved the survival rate and prolonged the survival time of HCC patients, but it was also safe. ...
Adverse reactions were mild. CONCLUSIONS: DC-based therapy not only enhanced anti-tumor immunity, improved the survival rate a …
Immunomodulatory Effects of Current Targeted Therapies on Hepatocellular Carcinoma: Implication for the Future of Immunotherapy.
Lin YY, Tan CT, Chen CW, Ou DL, Cheng AL, Hsu C. Lin YY, et al. Semin Liver Dis. 2018 Nov;38(4):379-388. doi: 10.1055/s-0038-1673621. Epub 2018 Oct 24. Semin Liver Dis. 2018. PMID: 30357775
Studies of sorafenib comprised the majority (58 of the 71) of the research articles reviewed. Potentially beneficial effects on anti-tumor immunity may result from increased M1 polarization of macrophages and stimulation of CD8 T cell function. On the other hand, hi …
Studies of sorafenib comprised the majority (58 of the 71) of the research articles reviewed. Potentially beneficial effects on anti-tumo …