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Quoted phrase not found in phrase index: "Type I complement component 8 deficiency"
Page 1
A Point Mutation Creating a 3' Splice Site in C8A Is a Predominant Cause of C8alpha-gamma Deficiency in African Americans.
Densen P, Ackermann L, Saucedo L, Figueroa JE, Si ZH, Stoltzfus CM. Densen P, et al. J Immunol. 2020 Sep 15;205(6):1535-1539. doi: 10.4049/jimmunol.2000272. Epub 2020 Aug 7. J Immunol. 2020. PMID: 32769119 Free PMC article.
This assay generated spliced RNA containing the 10 bp insertion observed in the C8alpha mRNA of affected patients. In addition, in mutant RNA substrates, the new 3' splice site was preferentially recognized compared with wild-type. Preferential selection of the muta …
This assay generated spliced RNA containing the 10 bp insertion observed in the C8alpha mRNA of affected patients. In addition, in mu …
Anti-idiotypic antibodies derived against C8, C9 and perforin bind homologous restriction factor.
Young JD, Jiang S, Liu CC, Hasselkus-Light CS. Young JD, et al. J Immunol Methods. 1990 Mar 27;128(1):133-42. doi: 10.1016/0022-1759(90)90472-8. J Immunol Methods. 1990. PMID: 1691232
Type III E and the C8bp/HRF-deficient mutant lymphoblastoid cell line, however, are as susceptible to perforin-mediated lysis as type I E and wild-type lymphoblastoid cell line, respectively, indicating that C8bp/HRF does not play a role in protecting …
Type III E and the C8bp/HRF-deficient mutant lymphoblastoid cell line, however, are as susceptible to perforin-mediated lysis …
Influence of subinhibitory concentrations of cephalosporins on the serum sensitivity of Pseudomonas aeruginosa.
Darveau RP, Cunningham MD. Darveau RP, et al. J Infect Dis. 1990 Oct;162(4):914-21. doi: 10.1093/infdis/162.4.914. J Infect Dis. 1990. PMID: 2119402
Increased sensitivity to the bactericidal action of serum in the presence of cefepime was observed for several different clinical isolates. With the use of C8-deficient sera, the late components of the complement pathway were shown to be essential for …
Increased sensitivity to the bactericidal action of serum in the presence of cefepime was observed for several different clinical iso …
Induced expression of neuronal membrane attack complex and cell death by Alzheimer's beta-amyloid peptide.
Shen Y, Sullivan T, Lee CM, Meri S, Shiosaki K, Lin CW. Shen Y, et al. Brain Res. 1998 Jun 15;796(1-2):187-97. doi: 10.1016/s0006-8993(98)00346-1. Brain Res. 1998. PMID: 9689469
We demonstrated that mRNAs (C1q, C2, C3, C4, C5, C6, C7, C8 and C9) and proteins (C1q, C3 and C9) for the major components of the classical complement cascade are present in the SH-SY5Y neurotypic cells, indicating that neuronal cells can synthesize the necessary pr …
We demonstrated that mRNAs (C1q, C2, C3, C4, C5, C6, C7, C8 and C9) and proteins (C1q, C3 and C9) for the major components of the cla …
Enhanced reactive lysis of paroxysmal nocturnal hemoglobinuria erythrocytes by C5b-9 does not involve increased C7 binding or cell-bound C3b.
Rosenfeld SI, Jenkins DE Jr, Leddy JP. Rosenfeld SI, et al. J Immunol. 1985 Jan;134(1):506-11. J Immunol. 1985. PMID: 3964820
The most complement (C)-sensitive type of erythrocytes (E) occurring in paroxysmal nocturnal hemoglobinuria (type III PNH E) have previously been found to exhibit approximately twofold to fourfold greater lysis than normal human E when exposed to isolated hum …
The most complement (C)-sensitive type of erythrocytes (E) occurring in paroxysmal nocturnal hemoglobinuria (type III P …
Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.
Holguin MH, Fredrick LR, Bernshaw NJ, Wilcox LA, Parker CJ. Holguin MH, et al. J Clin Invest. 1989 Jul;84(1):7-17. doi: 10.1172/JCI114172. J Clin Invest. 1989. PMID: 2738160 Free PMC article.
The observation that type III erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH) are susceptible to hemolysis initiated by activated cobra venom factor complexes (CoFBb), whereas normal erythrocytes are resistant, implies that the PNH III cells are deficie …
The observation that type III erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH) are susceptible to hemolysis initiated …