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1989 1
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Page 1
Intratumoral Budding in Pretreatment Biopsies, among Tumor Microenvironmental Components, Can Predict Prognosis and Neoadjuvant Therapy Response in Colorectal Adenocarcinoma.
Yim K, Jang WM, Cho U, Sun S, Chong Y, Seo KJ. Yim K, et al. Medicina (Kaunas). 2022 Jul 12;58(7):926. doi: 10.3390/medicina58070926. Medicina (Kaunas). 2022. PMID: 35888645 Free PMC article.
Background and Objectives: The prediction of the prognosis and effect of neoadjuvant therapy is vital for patients with advanced or unresectable colorectal carcinoma (CRC). ...Conclusions: High-grade ITB in PBSs is a potential unfavorable prognostic factor fo …
Background and Objectives: The prediction of the prognosis and effect of neoadjuvant therapy is vital for patients with advanc …
An increase in the peripheral lymphocyte-to-monocyte ratio after primary site resection is associated with a prolonged survival in unresectable colorectal carcinoma.
Ichikawa N, Homma S, Yoshida T, Mitsuhashi T, Iijima H, Ogasawara K, Kazui K, Kamiizumi Y, Kawamata F, Taketomi A. Ichikawa N, et al. Surg Today. 2020 Jun;50(6):604-614. doi: 10.1007/s00595-019-01927-1. Epub 2019 Nov 30. Surg Today. 2020. PMID: 31786682
PURPOSE: The prognostic benefits of primary tumor resection in patients with unresectable distant metastatic colorectal cancer remain unclear. A high pre-treatment lymphocyte-to-monocyte ratio (LMR) was previously shown to be associated with a better prognosis. We a …
PURPOSE: The prognostic benefits of primary tumor resection in patients with unresectable distant metastatic colorectal cancer remain …
The significance of transarterial chemoembolization combined with systemic chemotherapy for patients with KRAS wild-type unresectable metachronous colorectal carcinoma with liver metastases.
Yu Q, Zhang L, Fan S, Huang L, Wang X, Xindun C. Yu Q, et al. J Cancer Res Ther. 2016 Dec;12(Supplement):C205-C211. doi: 10.4103/0973-1482.200603. J Cancer Res Ther. 2016. PMID: 28230018 Free article.
We compared the rate of patients converted to resection for liver metastases (LMs), overall survival among these groups, and assessed prognostic factors. RESULTS: The median interval time from resection of primary tumor to the diagnosis of CMLs was 12.0 months. ...Univaria …
We compared the rate of patients converted to resection for liver metastases (LMs), overall survival among these groups, and assessed pro …
Fluorouracil and recombinant alfa-2a-interferon: an active regimen against advanced colorectal carcinoma.
Wadler S, Schwartz EL, Goldman M, Lyver A, Rader M, Zimmerman M, Itri L, Weinberg V, Wiernik PH. Wadler S, et al. J Clin Oncol. 1989 Dec;7(12):1769-75. doi: 10.1200/JCO.1989.7.12.1769. J Clin Oncol. 1989. PMID: 2585018
A total of 30 patients were enrolled; all were evaluable. 5FU was administered as a loading course, 750 mg/m2 daily for 5 days by continuous infusion followed by weekly bolus therapy, rIFN alpha-2a, 9 MU, was administered subcutaneously three times per week. ...
A total of 30 patients were enrolled; all were evaluable. 5FU was administered as a loading course, 750 mg/m2 daily for 5 days by con …
The usefulness of pharmacokinetic modulating chemotherapy (UFT plus 5FU) in the treatment of unresectable colorectal carcinomas.
Kusunoki M, Yanagi H, Noda M, Yamamura T. Kusunoki M, et al. Oncol Rep. 1999 May-Jun;6(3):547-52. doi: 10.3892/or.6.3.547. Oncol Rep. 1999. PMID: 10203589 Clinical Trial.
This study was performed to improve the prognosis of unresectable (primary non-curative and recurrent) colorectal carcinoma by using pharmacokinetic modulating chemotherapy (PMC), a combination of oral UFT and continuous venous 5FU infusion. ...One of 56 patients who recei …
This study was performed to improve the prognosis of unresectable (primary non-curative and recurrent) colorectal carcinoma by using …
Echogenicity of liver metastases from colorectal carcinoma is an independent prognostic factor in patients treated with regional chemotherapy.
Gruenberger T, Zhao J, King J, Chung T, Clingan PR, Morris DL. Gruenberger T, et al. Cancer. 2002 Mar 15;94(6):1753-9. doi: 10.1002/cncr.10386. Cancer. 2002. PMID: 11920538 Free article.

BACKGROUND: Echogenicity of liver metastases was found to be a predictive biologic factor influencing long-term outcome after curative liver resection. ...Echogenicity was identified as an independent prognostic factor in multivariate analysis (P < 0.009). CONCLU

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BACKGROUND: Echogenicity of liver metastases was found to be a predictive biologic factor influencing long-term outcome after curativ …
Treatment of patients with advanced colorectal cancer with cisplatin, 5-fluorouracil, and leucovorin.
Scheithauer W, Rosen H, Schiessel R, Schüller J, Karall M, Ernst F, Sebesta C, Kornek G, Hentschel E, Marczell A, et al. Scheithauer W, et al. Cancer. 1991 Mar 1;67(5):1294-8. doi: 10.1002/1097-0142(19910301)67:5<1294::aid-cncr2820670504>3.0.co;2-m. Cancer. 1991. PMID: 1991292 Clinical Trial.
Fifty-nine patients were enrolled in the study and 12 of them had received prior conventional 5-FU chemotherapy. Treatment consisted of 4 weekly courses of high-dose LV (200 mg/m2) administered by intravenous (IV) bolus, followed by 5-FU (550 mg/m2) and CDDP (20 mg/m2) eac …
Fifty-nine patients were enrolled in the study and 12 of them had received prior conventional 5-FU chemotherapy. Treatment consisted of 4 we …
Twelve-year experience of radioembolization for colorectal hepatic metastases in 214 patients: survival by era and chemotherapy.
Lewandowski RJ, Memon K, Mulcahy MF, Hickey R, Marshall K, Williams M, Salzig K, Gates VL, Atassi B, Vouche M, Atassi R, Desai K, Hohlastos E, Sato K, Habib A, Kircher S, Newman SB, Nimeiri H, Benson AB, Salem R. Lewandowski RJ, et al. Eur J Nucl Med Mol Imaging. 2014 Oct;41(10):1861-9. doi: 10.1007/s00259-014-2799-2. Epub 2014 Jun 7. Eur J Nucl Med Mol Imaging. 2014. PMID: 24906565
Multivariate analyses identified 2 cytotoxic agents, no exposure to biologics, ECOG 0, tumor burden <25 %, lack of extrahepatic disease and albumin >3 g/dL as independent predictors of survival. CONCLUSION: In this largest metastatic CRC series published to date, Y90 …
Multivariate analyses identified 2 cytotoxic agents, no exposure to biologics, ECOG 0, tumor burden <25 %, lack of extrahepatic disease a …