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Quoted phrase not found in phrase index: "Uveal Melanoma by Gene Expression Profile"
Page 1
Uveal Melanoma Treatment and Prognostication.
Dogrusöz M, Jager MJ, Damato B. Dogrusöz M, et al. Asia Pac J Ophthalmol (Phila). 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. Asia Pac J Ophthalmol (Phila). 2017. PMID: 28399342 Free article. Review.
Approximately 90% of uveal melanoma develop in the choroid, with the remainder arising in the ciliary body or the iris. The treatment of uveal melanoma is aimed at conserving the eye and useful vision, and, if possible, preventing metastatic disease. . …
Approximately 90% of uveal melanoma develop in the choroid, with the remainder arising in the ciliary body or the iris. The tr …
Iris melanoma: Prognostication for metastasis.
Melendez-Moreno A, Yeşiltaş YS, Wrenn J, Singh AD. Melendez-Moreno A, et al. Surv Ophthalmol. 2023 Sep-Oct;68(5):957-963. doi: 10.1016/j.survophthal.2023.05.006. Epub 2023 May 18. Surv Ophthalmol. 2023. PMID: 37207703 Review.
Uveal melanoma prognostication studies have mainly included posterior uveal melanomas located in the ciliary body and choroid, often excluding iris melanoma. ...In total, 9 cases demonstrated disomy 3, 2 cases with monosomy 3 (fluorescence in situ hybridizati …
Uveal melanoma prognostication studies have mainly included posterior uveal melanomas located in the ciliary body and c …
TAP1, a potential immune-related prognosis biomarker with functional significance in uveal melanoma.
Zhu R, Chen YT, Wang BW, You YY, Wang XH, Xie HT, Jiang FG, Zhang MC. Zhu R, et al. BMC Cancer. 2023 Feb 11;23(1):146. doi: 10.1186/s12885-023-10527-9. BMC Cancer. 2023. PMID: 36774490 Free PMC article.
BACKGROUND: TAP1 is an immunomodulation-related protein that plays different roles in various malignancies. This study investigated the transcriptional expression profile of TAP1 in uveal melanoma (UVM), revealed its potential biological interaction ne …
BACKGROUND: TAP1 is an immunomodulation-related protein that plays different roles in various malignancies. This study investigated the tran …
Prognostic and predictive biomarkers in melanoma.
Maher NG, Vergara IA, Long GV, Scolyer RA. Maher NG, et al. Pathology. 2024 Mar;56(2):259-273. doi: 10.1016/j.pathol.2023.11.004. Epub 2023 Dec 20. Pathology. 2024. PMID: 38245478 Review.
Gene expression profile assays and nomograms are emerging tools for prognostication and sentinel lymph node risk prediction in primary melanoma patients. ...Further research, validation, and assessment of clinical utility is required before more …
Gene expression profile assays and nomograms are emerging tools for prognostication and sentinel lymph node risk …
Development and validation of an immune and stromal prognostic signature in uveal melanoma to guide clinical therapy.
Gong Q, Wan Q, Li A, Yu Y, Ding X, Lin L, Qi X, Hu L. Gong Q, et al. Aging (Albany NY). 2020 Oct 26;12(20):20254-20267. doi: 10.18632/aging.103779. Epub 2020 Oct 26. Aging (Albany NY). 2020. PMID: 33100273 Free PMC article.
The tumor microenvironment is known to play an important role in uveal melanoma. Reliable prognostic signatures are needed to aid high risk patients and improve prognosis. Uveal melanoma tissues from three public datasets were analyzed. . …
The tumor microenvironment is known to play an important role in uveal melanoma. Reliable prognostic signatures are nee …
Cross-Platform Identification and Validation of Uveal Melanoma Vitreous Protein Biomarkers.
Velez G, Wolf J, Dufour A, Mruthyunjaya P, Mahajan VB. Velez G, et al. Invest Ophthalmol Vis Sci. 2023 Nov 1;64(14):14. doi: 10.1167/iovs.64.14.14. Invest Ophthalmol Vis Sci. 2023. PMID: 37955612 Free PMC article.
PURPOSE: The purpose of this study was to profile protein expression liquid vitreous biopsies from patients with uveal melanoma (UM) using mass spectrometry to identify prognostic biomarkers, signaling pathways, and therapeutic targets. ...CONCL …
PURPOSE: The purpose of this study was to profile protein expression liquid vitreous biopsies from patients with uveal …
The pathology of ocular cancer.
Eagle RC Jr. Eagle RC Jr. Eye (Lond). 2013 Feb;27(2):128-36. doi: 10.1038/eye.2012.237. Epub 2012 Nov 16. Eye (Lond). 2013. PMID: 23154492 Free PMC article. Review.
Uveal melanoma kills about half of affected patients. Most succumb to hepatic metastases, which are unresponsive to current therapy. Factors indicative of poor prognosis include tumor size, ciliary body involvement, epithelioid cells, extraocular extension, l …
Uveal melanoma kills about half of affected patients. Most succumb to hepatic metastases, which are unresponsive to current th …
Structure prediction of novel isoforms from uveal melanoma by AlphaFold.
Zhang Z, Li C, Li Q, Su X, Li J, Zhu L, Lin XJ, Shen J. Zhang Z, et al. Sci Data. 2023 Aug 4;10(1):513. doi: 10.1038/s41597-023-02429-z. Sci Data. 2023. PMID: 37542084 Free PMC article.
However, with the release of AlphaFold, which predicts three-dimensional models of proteins, this challenge is rapidly being overcome. Here, we present a dataset of 315 predicted structures of abnormal isoforms in 18 uveal melanoma patients based on se …
However, with the release of AlphaFold, which predicts three-dimensional models of proteins, this challenge is rapidly being overcome …
Update on uveal melanoma: Translational research from biology to clinical practice (Review).
Ortega MA, Fraile-Martínez O, García-Honduvilla N, Coca S, Álvarez-Mon M, Buján J, Teus MA. Ortega MA, et al. Int J Oncol. 2020 Dec;57(6):1262-1279. doi: 10.3892/ijo.2020.5140. Epub 2020 Oct 22. Int J Oncol. 2020. PMID: 33173970 Free PMC article. Review.
Uveal melanoma is the most common type of intraocular cancer with a low mean annual incidence of 5-10 cases per million. ...The anatomopathological study of uveal melanoma has recently benefited from developments in molecular biology. ...
Uveal melanoma is the most common type of intraocular cancer with a low mean annual incidence of 5-10 cases per million. ...Th …
Validation of the Prognostic Usefulness of the Gene Expression Profiling Test in Patients with Uveal Melanoma.
Miguez S, Lee RY, Chan AX, Demkowicz PC, Jones BSCL, Long CP, Abramson DH, Bosenberg M, Sznol M, Kluger H, Goldbaum MH, Francis JH, Pointdujour-Lim R, Bakhoum MF. Miguez S, et al. Ophthalmology. 2023 Jun;130(6):598-607. doi: 10.1016/j.ophtha.2023.01.020. Epub 2023 Feb 4. Ophthalmology. 2023. PMID: 36739981
PURPOSE: To validate the prognostic usefulness of gene expression profile (GEP) testing in patients with uveal melanoma. ...Patients with class 2 tumors showed an observed 5-year MFS of 47.5% (95% CI, 36.0%-62.8%). CONCLUSIONS: Tumor size …
PURPOSE: To validate the prognostic usefulness of gene expression profile (GEP) testing in patients with uvea …
103 results