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47 results

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Page 1
New-onset aplastic anemia after SARS-CoV-2 vaccination.
Chatzikalil E, Kattamis A, Diamantopoulos P, Solomou EE. Chatzikalil E, et al. Int J Hematol. 2023 Dec;118(6):667-681. doi: 10.1007/s12185-023-03666-z. Epub 2023 Sep 28. Int J Hematol. 2023. PMID: 37768509 Review.
The time from vaccination to onset of aplastic anemia ranged from 1 day to 7 months, with a median of 2.5 weeks. Seventeen patients were diagnosed with severe or very severe aplastic anemia post-vaccination and all patients received standard treatments …
The time from vaccination to onset of aplastic anemia ranged from 1 day to 7 months, with a median of 2.5 weeks. Seventeen patients were dia …
A New Immunosuppressive Therapy for Very Severe Aplastic Anemia in Children with Autoantibodies.
Wang ZJ, Chen HB, Zhou F, Yu H, Wu XY, Shen YQ, Qiu YN, Jin RM. Wang ZJ, et al. Curr Med Sci. 2022 Apr;42(2):379-386. doi: 10.1007/s11596-022-2519-2. Epub 2022 Mar 8. Curr Med Sci. 2022. PMID: 35258748
OBJECTIVE: At present, a number of very severe aplastic anemia (VSAA) patients cannot receive hematopoietic stem cell transplantation (HSCT) or standard immunosuppressive therapy (IST) due to the high cost of therapy, shortage of sibling donors, and la …
OBJECTIVE: At present, a number of very severe aplastic anemia (VSAA) patients cannot receive hematopoietic stem …
Supportive care in severe and very severe aplastic anemia.
Höchsmann B, Moicean A, Risitano A, Ljungman P, Schrezenmeier H. Höchsmann B, et al. Bone Marrow Transplant. 2013 Feb;48(2):168-73. doi: 10.1038/bmt.2012.220. Epub 2012 Dec 3. Bone Marrow Transplant. 2013. PMID: 23208312 Review.
In fact, many recommendations for patients with AA are not based on randomized studies in AA itself, but they are deduced from other conditions with similar severity of cytopenia. ...
In fact, many recommendations for patients with AA are not based on randomized studies in AA itself, but they are deduced from other …
Development and validation of early death risk score model for emergency status prediction in very severe aplastic anemia.
Liu X, Yang W, Zhang L, Jing L, Ye L, Zhou K, Li Y, Li J, Fan H, Yang Y, Xiong Y, Zhao X, Zhang F. Liu X, et al. Front Immunol. 2023 Apr 20;14:1175048. doi: 10.3389/fimmu.2023.1175048. eCollection 2023. Front Immunol. 2023. PMID: 37153568 Free PMC article.
This study developed and validated the Early Death Risk Score Model for early identification of emergency patients with very severe aplastic anemia (VSAA). All 377 patients with VSAA receiving first-line immunosuppressive therapy (IST) were categorized …
This study developed and validated the Early Death Risk Score Model for early identification of emergency patients with very sever
Immunosuppressive therapy in aplastic anemia.
Gupta V, Kumar A, Tilak V, Saini I, Bhatia B. Gupta V, et al. Indian J Pediatr. 2012 Dec;79(12):1587-91. doi: 10.1007/s12098-012-0691-2. Epub 2012 Jan 25. Indian J Pediatr. 2012. PMID: 22274992
METHODS: Thirty patients (19 boys and 11 girls) with aplastic anemia received antithymocyte globulin and cyclosporine. Twenty-two patients had severe and 8 had very severe aplastic anemia. RESULTS: Mean age of the patients was 9.19 2.56 y. ...
METHODS: Thirty patients (19 boys and 11 girls) with aplastic anemia received antithymocyte globulin and cyclosporine. Twenty-two patients h …
Adult aplastic anemia in Thailand: incidence and treatment outcome from a prospective nationwide population-based study.
Norasetthada L, Wongkhantee S, Chaipokam J, Charoenprasert K, Chuncharunee S, Rojnuckarin P, Sirijerachai C, Wanachiwanawin W, Issaragrisil S; Thai Aplastic Anemia Study Group. Norasetthada L, et al. Ann Hematol. 2021 Oct;100(10):2443-2452. doi: 10.1007/s00277-021-04566-0. Epub 2021 Jul 16. Ann Hematol. 2021. PMID: 34269837 Free PMC article.
There were 348 newly diagnosed adult AA patients during the enrollment period, giving an annual incidence of 4.6 per million. The incidence of severe (SAA) and very severe aplastic anemia (VSAA) (3.8 per million) was higher than non-severe AA (NSAA, 0. …
There were 348 newly diagnosed adult AA patients during the enrollment period, giving an annual incidence of 4.6 per million. The incidence …
Plain language summary of RACE study results: addition of eltrombopag to standard treatment of severe aplastic anemia.
de Latour RP, Kulasekararaj A, Iacobelli S, Griffin M, Halkes CJ, Dufour C, Risitano AM. de Latour RP, et al. Immunotherapy. 2024 Feb;16(3):135-142. doi: 10.2217/imt-2023-0200. Epub 2023 Dec 13. Immunotherapy. 2024. PMID: 38088156 Review.
WHAT IS THIS SUMMARY ABOUT? Severe aplastic anemia (SAA) and very severe aplastic anemia (vSAA) are blood diseases of the bone marrow. ...At this time, eltrombopag is only approved in specific countries to treat the condition under study that is discus …
WHAT IS THIS SUMMARY ABOUT? Severe aplastic anemia (SAA) and very severe aplastic anemia (vSAA) are blood diseas …
Efficacy and safety of equine anti-thymocyte immunoglobulin (eATG) in three Japanese patients with moderate to very severe aplastic anemia: a case series.
Kanda Y, Mori T, Narita A, Wolter KD, Yoshimatsu H, Nishimura K. Kanda Y, et al. Int J Hematol. 2023 Jan;117(1):37-43. doi: 10.1007/s12185-022-03496-5. Epub 2022 Nov 28. Int J Hematol. 2023. PMID: 36441357 Free PMC article.
In this case series, the efficacy and safety of PF-06462700, administered intravenously at 40 mg/kg/day for 4 days, were assessed over a 24-week period. This was as an open-label, single-arm, multicenter clinical study designed to enroll a minimum of three Japanese partici …
In this case series, the efficacy and safety of PF-06462700, administered intravenously at 40 mg/kg/day for 4 days, were assessed over a 24- …
Clinical characteristics of hepatitis-associated aplastic anemia in children.
Fu L, Zhang J, Wang R, Yang B, Li H, Chen H, Ma J. Fu L, et al. Ann Hematol. 2024 Feb;103(2):397-404. doi: 10.1007/s00277-023-05566-y. Epub 2023 Dec 12. Ann Hematol. 2024. PMID: 38082101
To understand the current situation of hepatitis-related aplastic anemia (HAAA) in children, we analyzed the patients with HAAA admitted to our hospital in the past 5 years to understand the disease characteristics and prognosis. The clinical data of patients with HAAA adm …
To understand the current situation of hepatitis-related aplastic anemia (HAAA) in children, we analyzed the patients with HAAA admitted to …
Acute hepatitis as a prequel to very severe aplastic anemia.
Weiler-Normann C, Hartl J, Weidemann S, von Pein UM, Fiedler W, Schramm C, Brinkert F, Kröger N, Christopeit M. Weiler-Normann C, et al. Z Gastroenterol. 2018 Jan;56(1):51-54. doi: 10.1055/s-0043-121737. Epub 2018 Jan 9. Z Gastroenterol. 2018. PMID: 29316578 English.
47 results