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Spontaneous intramural duodenal hematoma in type 2B von Willebrand disease.
Eichele DD, Ross M, Tang P, Hutchins GF, Mailliard M. Eichele DD, et al. World J Gastroenterol. 2013 Nov 7;19(41):7205-8. doi: 10.3748/wjg.v19.i41.7205. World J Gastroenterol. 2013. PMID: 24222967 Free PMC article.
We report an unusual case of spontaneous intramural duodenal hematoma presenting as an intestinal obstruction associated with acute pancreatitis in a patient with established von Willebrand disease, type 2B. The patient presented with abrupt ons …
We report an unusual case of spontaneous intramural duodenal hematoma presenting as an intestinal obstruction associated with acute pancreat …
Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B.
Rayes J, Hollestelle MJ, Legendre P, Marx I, de Groot PG, Christophe OD, Lenting PJ, Denis CV. Rayes J, et al. Blood. 2010 Jun 10;115(23):4870-7. doi: 10.1182/blood-2009-11-254193. Epub 2010 Mar 3. Blood. 2010. PMID: 20200350 Free article.
Von Willebrand disease (VWD)-type 2B originates from a gain-of-function mutation in von Willebrand factor (VWF), resulting in enhanced platelet binding. Clinical manifestations include increased bleeding tendency, loss of large multimers, thrombocytopenia, and circulating …
Von Willebrand disease (VWD)-type 2B originates from a gain-of-function mutation in von Willebrand factor (VWF), resulting in enhanced plate …
Use of a thrombopoietin receptor agonist in von Willebrand disease type 2B (p.V1316M) with severe thrombocytopenia and intracranial hemorrhage.
Espitia O, Ternisien C, Agard C, Boisseau P, Denis CV, Fouassier M. Espitia O, et al. Platelets. 2017 Jul;28(5):518-520. doi: 10.1080/09537104.2016.1246717. Epub 2016 Nov 25. Platelets. 2017. PMID: 27885890
Following inefficient treatment of four platelet transfusions, immunoglobulins, and corticosteroids, we initiated treatment with a thrombopoietin (TPO) receptor agonist (eltrombopag 25 mg/d) with a good efficacy. Her mother and sister also had chronic thrombocytopenia. Clinica …
Following inefficient treatment of four platelet transfusions, immunoglobulins, and corticosteroids, we initiated treatment with a thrombopo …